메뉴 건너뛰기




Volumn 37, Issue 8, 1999, Pages 413-416

Pharmacokinetics and hemodynamic effects of diltiazem in healthy volunteers: Comparing resting with the effect of exercise

Author keywords

Diltiazem; Healthy volunteers; Hemodynamics; Pharmacokinetics

Indexed keywords

CORONARY VASODILATING AGENT; DILTIAZEM;

EID: 0032802308     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (16)
  • 1
    • 0015184317 scopus 로고
    • Exercise testing of patients with coronary heart disease. Principles and normal standards for evaluation
    • Bruce R 1971 Exercise testing of patients with coronary heart disease. Principles and normal standards for evaluation. Ann Clin Res 3: 323-332
    • (1971) Ann Clin Res , vol.3 , pp. 323-332
    • Bruce, R.1
  • 2
    • 0023220762 scopus 로고
    • Diltiazem pharmacokinetics in the rat and the relationship between its serum concentration and uterine and cardiovascular effects
    • Downing SJ, Edwards D, Hollingsworth M 1987 Diltiazem pharmacokinetics in the rat and the relationship between its serum concentration and uterine and cardiovascular effects. Br J Pharmacol 91: 735-745
    • (1987) Br J Pharmacol , vol.91 , pp. 735-745
    • Downing, S.J.1    Edwards, D.2    Hollingsworth, M.3
  • 3
    • 0022898436 scopus 로고
    • Pharmacokinetics of slow-release diltiazem and its effect on atrioventricular conduction in healthy volunteers
    • Gordin A, Pohto P, Sundberg S, Nykanen S, Haataja H, Mannisto P 1986 Pharmacokinetics of slow-release diltiazem and its effect on atrioventricular conduction in healthy volunteers. Eur J Clin Pharmcol 31: 423-426
    • (1986) Eur J Clin Pharmcol , vol.31 , pp. 423-426
    • Gordin, A.1    Pohto, P.2    Sundberg, S.3    Nykanen, S.4    Haataja, H.5    Mannisto, P.6
  • 4
    • 0022560352 scopus 로고
    • Pharmacodynamic aspects of intravenous diltiazem administration
    • Joyal M, Pieper J, Cremer K, Feldman R, Pepine C 1986 Pharmacodynamic aspects of intravenous diltiazem administration. Am Heart J 111: 54-61
    • (1986) Am Heart J , vol.111 , pp. 54-61
    • Joyal, M.1    Pieper, J.2    Cremer, K.3    Feldman, R.4    Pepine, C.5
  • 5
    • 0019786721 scopus 로고
    • The pharmacokinetics and pharmacology of oral diltiazem in normal volunteers
    • Kinney EL, Moskowitz RM, Zelis R 1981 The pharmacokinetics and pharmacology of oral diltiazem in normal volunteers. J Clin Pharmacol 21: 337-342
    • (1981) J Clin Pharmacol , vol.21 , pp. 337-342
    • Kinney, E.L.1    Moskowitz, R.M.2    Zelis, R.3
  • 6
    • 0029563019 scopus 로고
    • Gender differences in exercise and recovery blood pressure responses in normal volunteers given diltiazem
    • Klassen G, Yeung P, Barclay K, Hung O, Pollak P, Buckley S 1995 Gender differences in exercise and recovery blood pressure responses in normal volunteers given diltiazem. J Clin Pharmacol 35: 1144-1149
    • (1995) J Clin Pharmacol , vol.35 , pp. 1144-1149
    • Klassen, G.1    Yeung, P.2    Barclay, K.3    Hung, O.4    Pollak, P.5    Buckley, S.6
  • 7
    • 1842331533 scopus 로고    scopus 로고
    • Safety of calcium channel blockers
    • Medical Letter 1997 Safety of calcium channel blockers. Med Lett 39: 13-16
    • (1997) Med Lett , vol.39 , pp. 13-16
  • 8
    • 0023268239 scopus 로고
    • Responses to intravenous and oral diltiazem in elderly and younger patients with systemic hypertension
    • Schwartz JB, Abernethy DR 1987 Responses to intravenous and oral diltiazem in elderly and younger patients with systemic hypertension. Am J Cardiol 59: 1111-1117
    • (1987) Am J Cardiol , vol.59 , pp. 1111-1117
    • Schwartz, J.B.1    Abernethy, D.R.2
  • 10
    • 0031887985 scopus 로고    scopus 로고
    • Pharmacokinetics and haemodynamic effects of diltiazem in rats: Effect of route of administration
    • Tsui B, Feng J, Yeung P 1998 Pharmacokinetics and haemodynamic effects of diltiazem in rats: Effect of route of administration. J Pharm Pharmacol 50: 183-188
    • (1998) J Pharm Pharmacol , vol.50 , pp. 183-188
    • Tsui, B.1    Feng, J.2    Yeung, P.3
  • 11
    • 0028930754 scopus 로고
    • Diltiazem: Ten years of clinical experience in the treatment of hypertension
    • Weir M 1995 Diltiazem: Ten years of clinical experience in the treatment of hypertension. J Clin Pharmacol 35: 220-232
    • (1995) J Clin Pharmacol , vol.35 , pp. 220-232
    • Weir, M.1
  • 12
    • 0021918578 scopus 로고
    • Cardiovascular effects of the metabolites of diltiazem in dogs
    • Yabana H, Nagao T, Sato M 1985 Cardiovascular effects of the metabolites of diltiazem in dogs. J Cardiovasc Pharmacol 7: 152-157
    • (1985) J Cardiovasc Pharmacol , vol.7 , pp. 152-157
    • Yabana, H.1    Nagao, T.2    Sato, M.3
  • 13
    • 0024953031 scopus 로고
    • High performance liquid chromatographic assay of diltiazem and six of its metabolites in plasma: Application to a pharmacokinetic study in healthy volunteers
    • Yeung PKF, Montague TJ, Tsui B, McGregor C 1989 High performance liquid chromatographic assay of diltiazem and six of its metabolites in plasma: Application to a pharmacokinetic study in healthy volunteers. J Pharm Sci 78: 592-597
    • (1989) J Pharm Sci , vol.78 , pp. 592-597
    • Yeung, P.K.F.1    Montague, T.J.2    Tsui, B.3    McGregor, C.4
  • 14
    • 0025887153 scopus 로고
    • Effect of diltiazem and its metabolites on the uptake of adenosine in blood: An in-vitro investigation
    • Yeung PKF, Mosher SJ, MacRae DA, Klassen GA 1991 Effect of diltiazem and its metabolites on the uptake of adenosine in blood: An in-vitro investigation. J Pharm Pharmacol 43: 685-689
    • (1991) J Pharm Pharmacol , vol.43 , pp. 685-689
    • Yeung, P.K.F.1    Mosher, S.J.2    MacRae, D.A.3    Klassen, G.A.4
  • 15
    • 0031790624 scopus 로고    scopus 로고
    • Pharmacokinetics and hypotensive effect of diltiazem in rabbits: Comparing diltiazem to its major metabolites
    • Yeung P, Feng J, Buckley S 1998a Pharmacokinetics and hypotensive effect of diltiazem in rabbits: comparing diltiazem to its major metabolites. J Pharm Pharmacol 50: 1247-1253
    • (1998) J Pharm Pharmacol , vol.50 , pp. 1247-1253
    • Yeung, P.1    Feng, J.2    Buckley, S.3
  • 16
    • 25344440931 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of diltiazem: Species differences
    • Yeung PKF, Feng JDZ, Klassen GA 1998b Pharmacokinetics and pharmacodynamics of diltiazem: Species differences. Pharm Sci Suppl 1: S-669
    • (1998) Pharm Sci , vol.1 , Issue.SUPPL.
    • Yeung, P.K.F.1    Feng, J.D.Z.2    Klassen, G.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.