An improved synthesis of (20R,22R)-cholest-5-ene-3β,20,22-triol, an intermediate in steroid hormone formation and an activator of nuclear orphan receptor LXRα

Steroids

Volumn 64, Issue 6, 1999, Pages 385-395

  Ruan, Benfang ^a   Wilson, William K ^a   Schroepfer Jr , George J ^a  

^a RICE UNIVERSITY   (United States)

Author keywords

(20R,22R) Cholest 5 ene 3 ; 20; 22 triol; AD mix; Ag+ HPLC; Asymmetric dihydroxylation; Conformational analysis; Molecular mechanics; NMR

Indexed keywords

20,22 DIHYDROXYCHOLESTEROL; CHOLESTEROL DERIVATIVE; STEROID RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHOLESTEROL METABOLISM; CONFORMATION; MOLECULAR DYNAMICS; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEROID HYDROXYLATION; STEROIDOGENESIS;

DNA-BINDING PROTEINS; HYDROXYCHOLESTEROLS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PREGNENOLONE; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0032798798     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(98)00116-0     Document Type: Article

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