-
1
-
-
0031694735
-
Antisense technology: Selection and delivery of optimally acting antisense oligonucleotides
-
Akhtar S (1998) Antisense technology: selection and delivery of optimally acting antisense oligonucleotides. J Drug Targeting 5: 225-234
-
(1998)
J Drug Targeting
, vol.5
, pp. 225-234
-
-
Akhtar, S.1
-
2
-
-
0031027349
-
In vivo studies with antisense oligonucleotides
-
Akhtar S and Agrawal S (1997) In vivo studies with antisense oligonucleotides. Trends Pharmacol Sci 18: 12-18
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 12-18
-
-
Akhtar, S.1
Agrawal, S.2
-
3
-
-
0030919006
-
Antisense oligonucleotide delivery to cultured macrophages is improved by incorporation into sustained-release biodegradable polymer microspheres
-
Akhtar S and Lewis KJ (1997) Antisense oligonucleotide delivery to cultured macrophages is improved by incorporation into sustained-release biodegradable polymer microspheres. Int J Pharmaceut 151: 57-67
-
(1997)
Int J Pharmaceut
, vol.151
, pp. 57-67
-
-
Akhtar, S.1
Lewis, K.J.2
-
4
-
-
0030743165
-
Control of differentiation, transformation, and apoptosis in granulosa cells by oncogenes, oncoviruses, and tumor suppressor genes
-
Amsterdam A and Selvaraj N (1997) Control of differentiation, transformation, and apoptosis in granulosa cells by oncogenes, oncoviruses, and tumor suppressor genes. Endocr Rev 18: 435-461
-
(1997)
Endocr Rev
, vol.18
, pp. 435-461
-
-
Amsterdam, A.1
Selvaraj, N.2
-
5
-
-
0032004794
-
Peptide nucleic acid (PNA) DNA hybrid duplexes; interealation by an internally linked anthraquinone
-
Armilage B, Koch T, Frydenlund H, Orum H and Schuster GB (1998) Peptide nucleic acid (PNA) DNA hybrid duplexes; interealation by an internally linked anthraquinone. Nucleic Acids Res 26: 715-720
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 715-720
-
-
Armilage, B.1
Koch, T.2
Frydenlund, H.3
Orum, H.4
Schuster, G.B.5
-
6
-
-
0002903579
-
Synthesis and properties of oligonucleotides covalently linked to interealating agents
-
Asselme U, Thoung NT and Helene C (1997) Synthesis and properties of oligonucleotides covalently linked to interealating agents. New J Chem 21: 5-17
-
(1997)
New J Chem
, vol.21
, pp. 5-17
-
-
Asselme, U.1
Thoung, N.T.2
Helene, C.3
-
8
-
-
0031759525
-
Strong, specific, reversible binding ligands for transfer RNA: Comparison by fluorescence and NMR spectroscopies with distamycin binding for a new structural class of ligand
-
Bichenkova EV, SadatEbrahimi SE, Wilton AN, Otoole N, Marks DS and Douglas KT (1998) Strong, specific, reversible binding ligands for transfer RNA: comparison by fluorescence and NMR spectroscopies with distamycin binding for a new structural class of ligand. Nucleosides Nucleotides 17: 1651-1665
-
(1998)
Nucleosides Nucleotides
, vol.17
, pp. 1651-1665
-
-
Bichenkova, E.V.1
SadatEbrahimi, S.E.2
Wilton, A.N.3
Otoole, N.4
Marks, D.S.5
Douglas, K.T.6
-
9
-
-
0032582736
-
Synthesis and evaluation of a carbocyclic analogue of the CC 1065 and duocarmycin alkylation subunits: Role of the vinylogous amide and implications on DNA alkylation catalysis
-
Boger DL and Turnbull P (1998) Synthesis and evaluation of a carbocyclic analogue of the CC 1065 and duocarmycin alkylation subunits: role of the vinylogous amide and implications on DNA alkylation catalysis. J Organic Chem 63: 8004-8011
-
(1998)
J Organic Chem
, vol.63
, pp. 8004-8011
-
-
Boger, D.L.1
Turnbull, P.2
-
10
-
-
0028915281
-
An assessment of the antisense properties of RNase H-competent and sterie-blocking oligomers
-
Bonham MA, Brown S, Boyd AL, Brown PH, Bruckenstein DA, Hanvey JC, Thomson SA. Pipe A, Hassman F, Bisi JE, Froehler BC, Matteucci MD, Wagner RW, Noble SA and Babiss LE (1995) An assessment of the antisense properties of RNase H-competent and sterie-blocking oligomers. Nucleic Acids Res 23: 1197-1203
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1197-1203
-
-
Bonham, M.A.1
Brown, S.2
Boyd, A.L.3
Brown, P.H.4
Bruckenstein, D.A.5
Hanvey, J.C.6
Thomson, S.A.7
Pipe, A.8
Hassman, F.9
Bisi, J.E.10
Froehler, B.C.11
Matteucci, M.D.12
Wagner, R.W.13
Noble, S.A.14
Babiss, L.E.15
-
11
-
-
0000507030
-
Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring system
-
Bose DS, Thompson AS, Ching JS, Hartley JA, Berardini MD, Jenkins TC, Neidle S, Hurley LH and Thurston DE (1992a) Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring system. J Am Chem Soc 114: 4939-4941
-
(1992)
J Am Chem Soc
, vol.114
, pp. 4939-4941
-
-
Bose, D.S.1
Thompson, A.S.2
Ching, J.S.3
Hartley, J.A.4
Berardini, M.D.5
Jenkins, T.C.6
Neidle, S.7
Hurley, L.H.8
Thurston, D.E.9
-
12
-
-
0026699259
-
Effect of linker length on DNA-binding affinity, cross linking efficiency and cytotoxicity of C8-linked pyrrolobenzodiazepine dimers
-
Bose DS, Thompson AS, Smellie M, Berardini MD, Hartley JA, Jenkins TC, Neidle S and Thurston DE (1992b) Effect of linker length on DNA-binding affinity, cross linking efficiency and cytotoxicity of C8-linked pyrrolobenzodiazepine dimers. J Chem Soc Chem Commun 1518-1520
-
(1992)
J Chem Soc Chem Commun
, pp. 1518-1520
-
-
Bose, D.S.1
Thompson, A.S.2
Smellie, M.3
Berardini, M.D.4
Hartley, J.A.5
Jenkins, T.C.6
Neidle, S.7
Thurston, D.E.8
-
13
-
-
0029851408
-
Nueleosome core particles inhibit DNA triple helix formation
-
Brown PM and Fox KR (1996) Nueleosome core particles inhibit DNA triple helix formation. Biochem J 319: 607-611
-
(1996)
Biochem J
, vol.319
, pp. 607-611
-
-
Brown, P.M.1
Fox, K.R.2
-
16
-
-
0032478124
-
A comparison of DNA-binding drugs as inhibitors of E12F1 and Sp1 DNA complexes and associated gene expression
-
Chiang SY, Azizkhan JC and Beerman TA (1998) A comparison of DNA-binding drugs as inhibitors of E12F1 and Sp1 DNA complexes and associated gene expression. Biochemistry 37: 3109-3115
-
(1998)
Biochemistry
, vol.37
, pp. 3109-3115
-
-
Chiang, S.Y.1
Azizkhan, J.C.2
Beerman, T.A.3
-
17
-
-
0028046895
-
Selection of DNA-binding sites for zinc fingers using rationally randomized DNA reveals coded interactions
-
Choo Y and Klug A (1994a) Selection of DNA-binding sites for zinc fingers using rationally randomized DNA reveals coded interactions. Proc Natl Acad Sci USA 91: 11168-11172
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11168-11172
-
-
Choo, Y.1
Klug, A.2
-
18
-
-
0027994717
-
Toward a code for the interactions of zinc fingers with DNA selection of randomized fingers displayed on phage
-
Choo Y and Klug A (1994b) Toward a code for the interactions of zinc fingers with DNA selection of randomized fingers displayed on phage. Proc Natl Acad Sci USA 91: 11163-11167
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11163-11167
-
-
Choo, Y.1
Klug, A.2
-
19
-
-
0028670569
-
In-vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
-
Choo Y, Sanchezgarcia I and Klug A (1994) In-vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence. Nature 372: 642-645
-
(1994)
Nature
, vol.372
, pp. 642-645
-
-
Choo, Y.1
Sanchezgarcia, I.2
Klug, A.3
-
20
-
-
0031592941
-
Promoter-specific activation of gene expression directed by bacteriophage-selected zinc fingers
-
Choo Y, Castellanos A, GarciaHernandez B, SanchezGarcia I and Klug A (1997) Promoter-specific activation of gene expression directed by bacteriophage-selected zinc fingers. J Mol Biol 273: 525-532
-
(1997)
J Mol Biol
, vol.273
, pp. 525-532
-
-
Choo, Y.1
Castellanos, A.2
GarciaHernandez, B.3
SanchezGarcia, I.4
Klug, A.5
-
21
-
-
0029295025
-
Solid phase synthesis of peptide nucleic acids
-
Christensen L, Fitzpatrick R, Gildea B, Petersen KH, Hansen MF, Koch T, Egholm M, Buchardt O, Nielsen PE, Coull J and Berg RH (1995) Solid phase synthesis of peptide nucleic acids. J Peptide Sci 1: 175-183
-
(1995)
J Peptide Sci
, vol.1
, pp. 175-183
-
-
Christensen, L.1
Fitzpatrick, R.2
Gildea, B.3
Petersen, K.H.4
Hansen, M.F.5
Koch, T.6
Egholm, M.7
Buchardt, O.8
Nielsen, P.E.9
Coull, J.10
Berg, R.H.11
-
22
-
-
0028129843
-
Stability of peptide nucleic-acids in human serum and cellular-extracts
-
Demidov VV, Potaman VN, Frankkamenetskii MD, Egholm M, Buchard O, Sonnichsen SH and Nielsen PE (1994) Stability of peptide nucleic-acids in human serum and cellular-extracts. Biochem Pharmacol 48: 1310-1313
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 1310-1313
-
-
Demidov, V.V.1
Potaman, V.N.2
Frankkamenetskii, M.D.3
Egholm, M.4
Buchard, O.5
Sonnichsen, S.H.6
Nielsen, P.E.7
-
23
-
-
33750249680
-
Gene-specific transcription inhibition in vivo by designed ligands
-
Dervan PB (1997) Gene-specific transcription inhibition in vivo by designed ligands. Faseb J II: 2546
-
(1997)
Faseb J
, vol.2
, pp. 2546
-
-
Dervan, P.B.1
-
24
-
-
0032573224
-
Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands
-
Dickinson LA, Gulizia RJ, Trauger JW, Baird EE, Mosier DE, Gottesfeld JM and Dervan PB (1998) Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proc Natl Acad Sci USA 95: 12890-12895
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 12890-12895
-
-
Dickinson, L.A.1
Gulizia, R.J.2
Trauger, J.W.3
Baird, E.E.4
Mosier, D.E.5
Gottesfeld, J.M.6
Dervan, P.B.7
-
25
-
-
0027364174
-
PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen bonding rules
-
Egholm M, Buchardt O, Christensen L, Behrens C, Freier SM, Driver DA, Berg RH, Kim SK, Norden B and Nielsen PE (1993) PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen bonding rules. Nature 365: 566-568
-
(1993)
Nature
, vol.365
, pp. 566-568
-
-
Egholm, M.1
Buchardt, O.2
Christensen, L.3
Behrens, C.4
Freier, S.M.5
Driver, D.A.6
Berg, R.H.7
Kim, S.K.8
Norden, B.9
Nielsen, P.E.10
-
26
-
-
0030664802
-
A novel peptide nucleic acid monomer for recognition of thymine in triple-helix structures
-
Eldrup AB, Dahl O and Nielsen PE (1997) A novel peptide nucleic acid monomer for recognition of thymine in triple-helix structures. J Am Chem Soc 119: 11116-11117
-
(1997)
J Am Chem Soc
, vol.119
, pp. 11116-11117
-
-
Eldrup, A.B.1
Dahl, O.2
Nielsen, P.E.3
-
27
-
-
0025074907
-
Invitro selection of RNA molecules that bind specific ligands
-
Ellington AD and Szostak JW (1990) Invitro selection of RNA molecules that bind specific ligands. Nature 346: 818-822
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
28
-
-
0028307974
-
Comparison of cellular and nuclear-flow cytometric techniques for discriminating apoptolic subpopulations
-
Elstein KH and Zucker RM (1994) Comparison of cellular and nuclear-flow cytometric techniques for discriminating apoptolic subpopulations. Exp Cell Res 211: 322-331
-
(1994)
Exp Cell Res
, vol.211
, pp. 322-331
-
-
Elstein, K.H.1
Zucker, R.M.2
-
29
-
-
0030440962
-
PNA nucleic acid complexes. Structure, stability and dynamics
-
Eriksson M and Nielsen PE (1996) PNA nucleic acid complexes. Structure, stability and dynamics. Quart Rev Biophys 29: 369-394
-
(1996)
Quart Rev Biophys
, vol.29
, pp. 369-394
-
-
Eriksson, M.1
Nielsen, P.E.2
-
30
-
-
0027715886
-
Stability of triple helices containing RNA and DNA strands: Experimental and molecular modeling studies
-
Escude C, Francois JC, Sun JS, Ott G, Sprinzl M, Garestier T and Helene C (1993) Stability of triple helices containing RNA and DNA strands: experimental and molecular modeling studies. Nucleic Acids Res 21: 5547-5553
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 5547-5553
-
-
Escude, C.1
Francois, J.C.2
Sun, J.S.3
Ott, G.4
Sprinzl, M.5
Garestier, T.6
Helene, C.7
-
31
-
-
13144266674
-
Rational design of a triple helix-specific intercalating ligand
-
Escude C, Nguyen CH, Kukreti S, Janin Y, Sun JS, Bisagni E, Garestier T and Helene C (1998) Rational design of a triple helix-specific intercalating ligand. Proc Natl Acad Sci USA 95: 3591-3396
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3591-13396
-
-
Escude, C.1
Nguyen, C.H.2
Kukreti, S.3
Janin, Y.4
Sun, J.S.5
Bisagni, E.6
Garestier, T.7
Helene, C.8
-
32
-
-
0029753770
-
Formation of triple-stranded DNA at d(GA center dot TC)(n) sequences prevents nucleosome assembly and is hindered by nucleosomes
-
Espinas ML, JimenezGarcia E, MartinezBalbas A and Azorin F (1996) Formation of triple-stranded DNA at d(GA center dot TC)(n) sequences prevents nucleosome assembly and is hindered by nucleosomes. J Biol Chem 271: 31807-31812
-
(1996)
J Biol Chem
, vol.271
, pp. 31807-31812
-
-
Espinas, M.L.1
JimenezGarcia, E.2
MartinezBalbas, A.3
Azorin, F.4
-
33
-
-
0023691730
-
Synthesis and DNA crosslinking ability of a dimeric anthramycin analog
-
Farmer JD, Rudnicki SM and Suggs JW (1998) Synthesis and DNA crosslinking ability of a dimeric anthramycin analog. Tetrahedron Lett 29: 5105-5108
-
(1998)
Tetrahedron Lett
, vol.29
, pp. 5105-5108
-
-
Farmer, J.D.1
Rudnicki, S.M.2
Suggs, J.W.3
-
34
-
-
0026080599
-
DNA-binding properties of a new class of linked anthramycin analogs
-
Farmer JD, Gustafson GR, Conti A, Zimmt MB and Suggs JW (1991) DNA-binding properties of a new class of linked anthramycin analogs. Nucleic Acids Res 19: 899-903
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 899-903
-
-
Farmer, J.D.1
Gustafson, G.R.2
Conti, A.3
Zimmt, M.B.4
Suggs, J.W.5
-
35
-
-
0030844046
-
Cellular uptake properties of 2′-amino/ 2′-O-methyl-modified hammerhead ribozymes targeted to the epidermal growth factor receptor mRNA
-
Fell P, Hudson AJ, Reynolds M, Usman N and Akhtar S (1997) Cellular uptake properties of 2′-amino/ 2′-O-methyl-modified hammerhead ribozymes targeted to the epidermal growth factor receptor mRNA. Antisense Nucleic Acid Drug Dev 7: 319-326
-
(1997)
Antisense Nucleic Acid Drug Dev
, vol.7
, pp. 319-326
-
-
Fell, P.1
Hudson, A.J.2
Reynolds, M.3
Usman, N.4
Akhtar, S.5
-
36
-
-
0028986037
-
Active dissociation of Hoechst-33342 from DNA in living mammalian cells
-
Filatov MV and Varfolomeeva EY (1995) Active dissociation of Hoechst-33342 from DNA in living mammalian cells. Mutation Res Fund Mol Mech Mutagen 327: 209-215
-
(1995)
Mutation Res Fund Mol Mech Mutagen
, vol.327
, pp. 209-215
-
-
Filatov, M.V.1
Varfolomeeva, E.Y.2
-
37
-
-
0027494882
-
Relative specificities in binding of Watson Crick base-pairs by 3rd strand residues in a DNA pyrimidine triplex motif
-
Fossella JA, Kim YJ, Shih H, Richards EG and Fresco JR (1903) Relative specificities in binding of Watson Crick base-pairs by 3rd strand residues in a DNA pyrimidine triplex motif. Nucleic Acids Res 21: 4511-4515
-
(1903)
Nucleic Acids Res
, vol.21
, pp. 4511-4515
-
-
Fossella, J.A.1
Kim, Y.J.2
Shih, H.3
Richards, E.G.4
Fresco, J.R.5
-
38
-
-
0030812914
-
Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids
-
Gilar M, Relenky A, Smisek DL, Bourque A and Cohen AS (1997) Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids. Nucleic Acids Res 25: 3615-3620
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 3615-3620
-
-
Gilar, M.1
Relenky, A.2
Smisek, D.L.3
Bourque, A.4
Cohen, A.S.5
-
39
-
-
0031033760
-
Accessibility of nuclear DNA to triplex-forming oligonucleotides: The integrated HIV-1 provirus as a target
-
Giovannangeli C, Diviacco S, Labrousse V, Gryaznov S, Charneau P and Helene C (1997) Accessibility of nuclear DNA to triplex-forming oligonucleotides: the integrated HIV-1 provirus as a target. Proc Natl Acad Sci USA 94: 79-84
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 79-84
-
-
Giovannangeli, C.1
Diviacco, S.2
Labrousse, V.3
Gryaznov, S.4
Charneau, P.5
Helene, C.6
-
41
-
-
0026720075
-
Tight control of gene-expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M and Bujard H (1992) Tight control of gene-expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89: 5547-5551
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
42
-
-
0030951207
-
Regulation of gene expression by small molecules
-
Gottesfeld JM, Neely L, Trauger JW, Baird EE and Dervan PB (1997) Regulation of gene expression by small molecules. Nature 387: 202-205
-
(1997)
Nature
, vol.387
, pp. 202-205
-
-
Gottesfeld, J.M.1
Neely, L.2
Trauger, J.W.3
Baird, E.E.4
Dervan, P.B.5
-
43
-
-
0024473767
-
Recognition of thymine: Adenine base-pairs by guanine in a pyrimidine triple helix motif
-
Griffin LC and Dervan PB (1989) Recognition of thymine: adenine base-pairs by guanine in a pyrimidine triple helix motif. Science 245: 967-971
-
(1989)
Science
, vol.245
, pp. 967-971
-
-
Griffin, L.C.1
Dervan, P.B.2
-
45
-
-
0032576660
-
DNA recognition: Reading the minor groove
-
Helene C (1998) DNA recognition: reading the minor groove. Nature 391: 436-438
-
(1998)
Nature
, vol.391
, pp. 436-438
-
-
Helene, C.1
-
46
-
-
0031933080
-
RNA as a drug target: Chemical, modelling, and evolutionary tools
-
Hermann T and Westhof E (1998) RNA as a drug target: chemical, modelling, and evolutionary tools. Curr Opin Biotechnol 9: 66-73
-
(1998)
Curr Opin Biotechnol
, vol.9
, pp. 66-73
-
-
Hermann, T.1
Westhof, E.2
-
47
-
-
0032564881
-
Stereochemical control of the DNA binding affinity, sequence specificity, and orientation preference of chiral hairpin polyamides in the minor groove
-
Herman DM, Baird EE and Dervan PB (1998) Stereochemical control of the DNA binding affinity, sequence specificity, and orientation preference of chiral hairpin polyamides in the minor groove. J Am Chem Soc 120: 1382-1391
-
(1998)
J Am Chem Soc
, vol.120
, pp. 1382-1391
-
-
Herman, D.M.1
Baird, E.E.2
Dervan, P.B.3
-
48
-
-
0022552540
-
DNA-sequence specificity of the pyrrolo[1,4]benzodiazepine antitumor antibiotics: Methidiumpropyl-EDTA-iron(II) footprinting analysis of DNA-binding sites for anthramycin and related drugs
-
Hertzberg RP, Hecht SM, Reynolds VL, Molineux IJ and Hurley LH (1986) DNA-sequence specificity of the pyrrolo[1,4]benzodiazepine antitumor antibiotics: methidiumpropyl-EDTA-iron(II) footprinting analysis of DNA-binding sites for anthramycin and related drugs. Biochemistry 25: 1249-1258
-
(1986)
Biochemistry
, vol.25
, pp. 1249-1258
-
-
Hertzberg, R.P.1
Hecht, S.M.2
Reynolds, V.L.3
Molineux, I.J.4
Hurley, L.H.5
-
49
-
-
0029938209
-
Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries
-
Ho SP, Brilton DHO, Stone BA, Behrens DL, Leffet LM, Hobbs FW, Miller JA and Trainor GL (1996) Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries. Nucleic Acids Res 24: 1901-1907
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 1901-1907
-
-
Ho, S.P.1
Brilton, D.H.O.2
Stone, B.A.3
Behrens, D.L.4
Leffet, L.M.5
Hobbs, F.W.6
Miller, J.A.7
Trainor, G.L.8
-
50
-
-
0023755904
-
Pyrrolo[I,4]benzodiazepine anlitumor antibiotics: Relationship of DNA alkyhition and sequence specificity to the biological activity of natural and synthetic compounds
-
Hurley LH, Reck T, Thurston DE, Langley DR, Holden KG, Hertzberg RP, Hoover JRF, Gallagher G Jnr, Faucette LF, Mong SM and Johnson RK (1988) Pyrrolo[I,4]benzodiazepine anlitumor antibiotics: relationship of DNA alkyhition and sequence specificity to the biological activity of natural and synthetic compounds. Chem Res Toxicol 1: 258-268
-
(1988)
Chem Res Toxicol
, vol.1
, pp. 258-268
-
-
Hurley, L.H.1
Reck, T.2
Thurston, D.E.3
Langley, D.R.4
Holden, K.G.5
Hertzberg, R.P.6
Hoover, J.R.F.7
Gallagher G., Jr.8
Faucette, L.F.9
Mong, S.M.10
Johnson, R.K.11
-
51
-
-
0030940295
-
Synergy between adjacent zinc fingers in sequence-specific DNA recognition
-
Isalan M, Choo Y and Klug A (1997) Synergy between adjacent zinc fingers in sequence-specific DNA recognition. Proc Natl Acad Sci USA 94: 5617-5621
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5617-5621
-
-
Isalan, M.1
Choo, Y.2
Klug, A.3
-
52
-
-
0032168890
-
Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers
-
Isalan M, Klug A and Choo Y (1998) Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers. Biochemistry 37: 12026-12033
-
(1998)
Biochemistry
, vol.37
, pp. 12026-12033
-
-
Isalan, M.1
Klug, A.2
Choo, Y.3
-
53
-
-
0028600121
-
Structure of a covalent DNA minor groove adduct with a pyrrolobenzodiazepine dimer: Evidence for sequence-specific interstrand cross-linking
-
Jenkins TC, Hurley LH, Neidle S and Thurston DE (1994) Structure of a covalent DNA minor groove adduct with a pyrrolobenzodiazepine dimer: evidence for sequence-specific interstrand cross-linking. J Med Chem 37: 4529-1537
-
(1994)
J Med Chem
, vol.37
, pp. 4529-11537
-
-
Jenkins, T.C.1
Hurley, L.H.2
Neidle, S.3
Thurston, D.E.4
-
54
-
-
0028290825
-
Control of RNA initiation and elongation at the HIV-1 promoter
-
Jones KA and Peterlin BM (1994) Control of RNA initiation and elongation at the HIV-1 promoter. Ann Rev Biochem 63 717-743
-
(1994)
Ann Rev Biochem
, vol.63
, pp. 717-743
-
-
Jones, K.A.1
Peterlin, B.M.2
-
55
-
-
0031933884
-
Structural basis for G center dot C recognition in the DNA minor groove
-
Kielkopf CL, Baird EE, Dervan PD and Rees DC (1998a) Structural basis for G center dot C recognition in the DNA minor groove. Nat Struct Biol 5: 104-109
-
(1998)
Nat Struct Biol
, vol.5
, pp. 104-109
-
-
Kielkopf, C.L.1
Baird, E.E.2
Dervan, P.D.3
Rees, D.C.4
-
56
-
-
0032475994
-
A structural basis for recognition of A center dot T and T center dot A base pairs in the minor groove of B-DNA
-
Kielkopf CL, White S, Szewczyk JW, Turner JM, Baird EE, Dervan PB and Rees DC (1998b) A structural basis for recognition of A center dot T and T center dot A base pairs in the minor groove of B-DNA. Science 282: 111-115
-
(1998)
Science
, vol.282
, pp. 111-115
-
-
Kielkopf, C.L.1
White, S.2
Szewczyk, J.W.3
Turner, J.M.4
Baird, E.E.5
Dervan, P.B.6
Rees, D.C.7
-
57
-
-
0001594480
-
Nonnatural deoxyribonucleoside-D(3) incorporated in an intramolecular DNA triplex binds sequence-specifically by interealation
-
Koshlap KM, Gillespie P, Denvan PB and Fergon J (1993) Nonnatural deoxyribonucleoside-D(3) incorporated in an intramolecular DNA triplex binds sequence-specifically by interealation. J Am Chem Soc 115: 7908-7909
-
(1993)
J Am Chem Soc
, vol.115
, pp. 7908-7909
-
-
Koshlap, K.M.1
Gillespie, P.2
Denvan, P.B.3
Fergon, J.4
-
58
-
-
0030711027
-
Extension of the range of DNA sequences available for triple helix formation: Stabilisation of mismatched triplexes by acridine-containing oligonucleotides
-
Kukreti S, Sun JS, Garestier T and Helene C (1997) Extension of the range of DNA sequences available for triple helix formation: stabilisation of mismatched triplexes by acridine-containing oligonucleotides. Nucleic Acids Res 25: 4264-1270
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4264-11270
-
-
Kukreti, S.1
Sun, J.S.2
Garestier, T.3
Helene, C.4
-
59
-
-
0013852032
-
Isolation and characterization of anthramycin, a new antitumour antibiotic
-
Leimgruber W, Stefanovic V, Shenker F, Karr A and Berger J (1965) Isolation and characterization of anthramycin, a new antitumour antibiotic. J Am Chem Soc 87: 5791-5793
-
(1965)
J Am Chem Soc
, vol.87
, pp. 5791-5793
-
-
Leimgruber, W.1
Stefanovic, V.2
Shenker, F.3
Karr, A.4
Berger, J.5
-
60
-
-
20144365291
-
DNA-binding ligands from peptide libraries containing unnatural amino acids
-
Lescrinier T, Hendrix C, Kerremans L, Rozenski J, Link A, Samyn P, VanAerschot A, Lescrinier E, Eritja R, VanBeeumen J and Herdewijn P (1998) DNA-binding ligands from peptide libraries containing unnatural amino acids. Chem Eur J 4: 425-433
-
(1998)
Chem Eur J
, vol.4
, pp. 425-433
-
-
Lescrinier, T.1
Hendrix, C.2
Kerremans, L.3
Rozenski, J.4
Link, A.5
Samyn, P.6
VanAerschot, A.7
Lescrinier, E.8
Eritja, R.9
VanBeeumen, J.10
Herdewijn, P.11
-
61
-
-
0031689425
-
Development of a sustained-release biodegradable polymer delivery system for site-specific delivery of oligonucleotides: Characterization of P(LA-GA) copolymer microspheres in vitro
-
Lewis KJ, Irwin WJ and Akhtar S (1998) Development of a sustained-release biodegradable polymer delivery system for site-specific delivery of oligonucleotides: characterization of P(LA-GA) copolymer microspheres in vitro. J Drug Target 5: 291-302
-
(1998)
J Drug Target
, vol.5
, pp. 291-302
-
-
Lewis, K.J.1
Irwin, W.J.2
Akhtar, S.3
-
62
-
-
0030034725
-
Sequence-selective carbohydrate DNA interaction: Dimeric and monomeric forms of the calicheamicin oligosaccharide interfere with transcription factor function
-
Liu C, Smith BM, Ajito K, Komatsu H, GomezPaloma L, Li TH, Theodorakis EA, Nicolaou KC and Vogt PK (1996) Sequence-selective carbohydrate DNA interaction: dimeric and monomeric forms of the calicheamicin oligosaccharide interfere with transcription factor function. Proc Natl Acad Sci USA 93: 940-944
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 940-944
-
-
Liu, C.1
Smith, B.M.2
Ajito, K.3
Komatsu, H.4
GomezPaloma, L.5
Li, T.H.6
Theodorakis, E.A.7
Nicolaou, K.C.8
Vogt, P.K.9
-
63
-
-
0028942445
-
Design acid development of sequence selective lexitropsin DNA minor groove binders
-
Lown JW (1995) Design acid development of sequence selective lexitropsin DNA minor groove binders. Drug Dev Res 34: 145-183
-
(1995)
Drug Dev Res
, vol.34
, pp. 145-183
-
-
Lown, J.W.1
-
65
-
-
0009633408
-
DNA-bindnlg and biological-activity of the cyclopropyl enantiomer of the antitumor antibiotic CC-1065
-
McGrovren JP, Lee CS, Hurley LH, Li LH and Kelly RC (1987) DNA-bindnlg and biological-activity of the cyclopropyl enantiomer of the antitumor antibiotic CC-1065. Proc Am Assoc Cancer Res 28: 262
-
(1987)
Proc Am Assoc Cancer Res
, vol.28
, pp. 262
-
-
McGrovren, J.P.1
Lee, C.S.2
Hurley, L.H.3
Li, L.H.4
Kelly, R.C.5
-
66
-
-
17344367023
-
Targeted gene knockout mediated by triple helix forming oligonucleotides
-
Majumdar A, Khorlin A, Dyalkina N, Lin FLM, Powell J, Liu J, Feiz ZZ, Khripine Y, Watanabe KA, George J, Glazer PM and Seidman MM (1998) Targeted gene knockout mediated by triple helix forming oligonucleotides. Nat Genet 20: 212-214
-
(1998)
Nat Genet
, vol.20
, pp. 212-214
-
-
Majumdar, A.1
Khorlin, A.2
Dyalkina, N.3
Lin, F.L.M.4
Powell, J.5
Liu, J.6
Feiz, Z.Z.7
Khripine, Y.8
Watanabe, K.A.9
George, J.10
Glazer, P.M.11
Seidman, M.M.12
-
67
-
-
0029952811
-
In pursuit of antisense
-
Matteucci MD and Wagner RW (1996) In pursuit of antisense. Nature 384: 20-22
-
(1996)
Nature
, vol.384
, pp. 20-22
-
-
Matteucci, M.D.1
Wagner, R.W.2
-
68
-
-
0029262020
-
Antisense approaches to cancer gene-therapy
-
Mercola D and Cohen JS (1995) Antisense approaches to cancer gene-therapy. Cancer Gene Theraphy 2: 47-59
-
(1995)
Cancer Gene Theraphy
, vol.2
, pp. 47-59
-
-
Mercola, D.1
Cohen, J.S.2
-
69
-
-
0031772021
-
Designing novel KNA binders
-
Michael K and Tor Y (1998) Designing novel KNA binders. Chem Eur J 4: 2091-2098
-
(1998)
Chem Eur J
, vol.4
, pp. 2091-2098
-
-
Michael, K.1
Tor, Y.2
-
70
-
-
0030902471
-
Selecting effective antisense reagents on combinatorial oligonucleotide arrays
-
Milner N, Mir KU and Southern EM (1997) Selecting effective antisense reagents on combinatorial oligonucleotide arrays. Nature Biotechnol 15: 537-541
-
(1997)
Nature Biotechnol
, vol.15
, pp. 537-541
-
-
Milner, N.1
Mir, K.U.2
Southern, E.M.3
-
71
-
-
0032522278
-
Additive antisense effects of different PNAs on the in vitro translation of the PML/RAR alpha gene
-
Mologni L, leCoutre P, Nielsen PE and GambacortiPasserini C (1998) Additive antisense effects of different PNAs on the in vitro translation of the PML/RAR alpha gene. Nucleic Acids Res 26: 1934-1938
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 1934-1938
-
-
Mologni, L.1
LeCoutre, P.2
Nielsen, P.E.3
GambacortiPasserini, C.4
-
72
-
-
0030760355
-
First-and second-generation antisense inhibitors targeted to human c-rafkinase: In vitro and in vivo studies
-
Monia BP (1997) First-and second-generation antisense inhibitors targeted to human c-rafkinase: in vitro and in vivo studies. Anti-Cancer Drug Design 12: 327-339
-
(1997)
Anti-Cancer Drug Design
, vol.12
, pp. 327-339
-
-
Monia, B.P.1
-
73
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
-
Monia BP, Johnston JF, Geiger T, Muller M and Fabbro D (1996a) Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat Med 2: 668-675
-
(1996)
Nat Med
, vol.2
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
Muller, M.4
Fabbro, D.5
-
74
-
-
12644268252
-
Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-rafkinase supports an antisense mechanism of action in vivo
-
Monia BP, Sasmor H, Johnston JF, Freier SM, Lesnik EA, Muller M, Geiger T, Altmann KH, Moser H and Fabbro D (1996b) Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-rafkinase supports an antisense mechanism of action in vivo. Proc Natl Acad Sci USA 93: 15481-15484
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15481-15484
-
-
Monia, B.P.1
Sasmor, H.2
Johnston, J.F.3
Freier, S.M.4
Lesnik, E.A.5
Muller, M.6
Geiger, T.7
Altmann, K.H.8
Moser, H.9
Fabbro, D.10
-
75
-
-
0028063086
-
Comparison of a DSB-120 DNA interstrand cross-linked adduct with the corresponding bis-tomaymycin adduct: An example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin
-
Mountzouris JA, Wang JJ, Thurston DE and Hurley LH (1994) Comparison of a DSB-120 DNA interstrand cross-linked adduct with the corresponding bis-tomaymycin adduct: an example of a successful template-directed approach to drug design based upon the monoalkylating compound tomaymycin. J Med Chem 37: 3132-3140
-
(1994)
J Med Chem
, vol.37
, pp. 3132-3140
-
-
Mountzouris, J.A.1
Wang, J.J.2
Thurston, D.E.3
Hurley, L.H.4
-
76
-
-
0026661689
-
Antiparallel side-by-side dimeric motil for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin
-
Mrksieh M, Wade WS, Dwyer TJ, Geierstanger BH, Wemmer DE and Dervan PB (1992) Antiparallel side-by-side dimeric motil for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin. Proc Natl Acad Sci USA 89: 7586-7590
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7586-7590
-
-
Mrksieh, M.1
Wade, W.S.2
Dwyer, T.J.3
Geierstanger, B.H.4
Wemmer, D.E.5
Dervan, P.B.6
-
77
-
-
0027970146
-
Hairpin peptide motif: A new class of oligopeptides for sequence-specific recognition in the minor-groove of double-helical DNA
-
Mrksieh M, Parks ME and Dervan PB (1994) Hairpin peptide motif: a new class of oligopeptides for sequence-specific recognition in the minor-groove of double-helical DNA. J Am Chem Soc 116: 7983-7988
-
(1994)
J Am Chem Soc
, vol.116
, pp. 7983-7988
-
-
Mrksieh, M.1
Parks, M.E.2
Dervan, P.B.3
-
78
-
-
0030861344
-
Recent developments in triple-helix regulation of gene expression
-
Neidle S (1997) Recent developments in triple-helix regulation of gene expression. Anticancer Drug Design 12: 433-442
-
(1997)
Anticancer Drug Design
, vol.12
, pp. 433-442
-
-
Neidle, S.1
-
79
-
-
0003701319
-
DNA sequences as targets for new anticancer agents
-
Kerr DJ and Workman P (eds) Boca Raton, Florida: CRC Press Ltd.
-
Neidle S and Thurston DE (1994) DNA sequences as targets for new anticancer agents. In: New Targets for Cancer Chemotherapy. Kerr DJ and Workman P (eds), pp. 159-175. Boca Raton, Florida: CRC Press Ltd.
-
(1994)
New Targets for Cancer Chemotherapy
, pp. 159-175
-
-
Neidle, S.1
Thurston, D.E.2
-
80
-
-
0028232159
-
The relevance of drug-DNA sequence specificity to antitumor activity
-
Neidle S, Puvvada MS and Thurston DE (1994) The relevance of drug-DNA sequence specificity to antitumor activity. Eur J Cancer 30A: 567-568
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 567-568
-
-
Neidle, S.1
Puvvada, M.S.2
Thurston, D.E.3
-
81
-
-
0026341239
-
Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
-
Nielsen PE, Egholm M, Berg RH and Buchardt O (1991) Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science 254: 1497-1500
-
(1991)
Science
, vol.254
, pp. 1497-1500
-
-
Nielsen, P.E.1
Egholm, M.2
Berg, R.H.3
Buchardt, O.4
-
82
-
-
0029865151
-
Ecdysone-inducible gene expression in mammalian cells and transgenic mice
-
No D, Yao TP and Evans RM (1996) Ecdysone-inducible gene expression in mammalian cells and transgenic mice. Proc Natl Acad Sci USA 93: 3346-3351
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3346-3351
-
-
No, D.1
Yao, T.P.2
Evans, R.M.3
-
83
-
-
0029904935
-
The chemical evolution of DNA-DNA interstrand cross-linkers that recognize defined mixed AT and GC sequences
-
Park HJ, Kelly RC and Hurley LH (1996) The chemical evolution of DNA-DNA interstrand cross-linkers that recognize defined mixed AT and GC sequences. J Am Chem Soc 118: 10041-10051
-
(1996)
J Am Chem Soc
, vol.118
, pp. 10041-10051
-
-
Park, H.J.1
Kelly, R.C.2
Hurley, L.H.3
-
84
-
-
0001015292
-
Structural characterization of a 2-1 distamycin a.D (CGCAAATTGGC) complex by two-dimensional NMR
-
Pelton JG and Wemmer DE (1989) Structural characterization of a 2-1 distamycin a.D (CGCAAATTGGC) complex by two-dimensional NMR. Proc Natl Acad Sci USA 86: 5723-5727
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5723-5727
-
-
Pelton, J.G.1
Wemmer, D.E.2
-
86
-
-
0024504005
-
Triple helix formation by oligonucleotides on DNA extended to the physiological pH range
-
Povsic TJ and Dervan PB (1989) Triple helix formation by oligonucleotides on DNA extended to the physiological pH range. J Am Chem Soc 111: 3059-3061
-
(1989)
J Am Chem Soc
, vol.111
, pp. 3059-3061
-
-
Povsic, T.J.1
Dervan, P.B.2
-
87
-
-
0027178818
-
A quantitative assay to measure the relative DNA-binding affinity of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor antibiotics based on the inhibition of restriction endonuclease [BamH 1]
-
Puvvada MS, Hartley JA, Jenkins TC and Thurston DE (1993) A quantitative assay to measure the relative DNA-binding affinity of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumor antibiotics based on the inhibition of restriction endonuclease [BamH 1]. Nucleic Acids Res 21: 3671-3675
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 3671-3675
-
-
Puvvada, M.S.1
Hartley, J.A.2
Jenkins, T.C.3
Thurston, D.E.4
-
88
-
-
0031017942
-
Inhibition of bacteriophage T7 RNA polymerase in vitro transcription by DNA-binding pyrrolo[2,1-c][1,4]benzodiazepines
-
Puvvada MS, Forrow SA, Hartley JA, Stephenson P, Gibson I, Jenkins TC and Thurston DE (1997) Inhibition of bacteriophage T7 RNA polymerase in vitro transcription by DNA-binding pyrrolo[2,1-c][1,4]benzodiazepines. Biochemistry 36: 2478-2484
-
(1997)
Biochemistry
, vol.36
, pp. 2478-2484
-
-
Puvvada, M.S.1
Forrow, S.A.2
Hartley, J.A.3
Stephenson, P.4
Gibson, I.5
Jenkins, T.C.6
Thurston, D.E.7
-
89
-
-
0009620928
-
A phase I study of bizelesin (NSC 615291) in solid tumors
-
Rayson D, Pilot HC, Reid JM, Ames MM, Bagniewski PG, Erlichman C, Sloan JA and Adjei AA (1998) A phase I study of bizelesin (NSC 615291) in solid tumors. Ann Oncol 9: 475
-
(1998)
Ann Oncol
, vol.9
, pp. 475
-
-
Rayson, D.1
Pilot, H.C.2
Reid, J.M.3
Ames, M.M.4
Bagniewski, P.G.5
Erlichman, C.6
Sloan, J.A.7
Adjei, A.A.8
-
90
-
-
0026063696
-
The Chinese Hamster Hprt gene: Restriction map, sequence-analysis, and multiplex PCR deletion screen
-
Rossiter BJE, Fuscoe JC, Muzny DM, Fox M and Caskey CT (1991) The Chinese Hamster Hprt gene: restriction map, sequence-analysis, and multiplex PCR deletion screen. Genomics 9: 247-256
-
(1991)
Genomics
, vol.9
, pp. 247-256
-
-
Rossiter, B.J.E.1
Fuscoe, J.C.2
Muzny, D.M.3
Fox, M.4
Caskey, C.T.5
-
91
-
-
0028082283
-
Phase I study of adozelesin (U-73,975) in patients with solid tumors
-
Shamdas GJ, Alberts DS, Modiano M, Wiggins C, Power J, Kasunic DA, Elfring GL and Earhart RH (1994) Phase I study of adozelesin (U-73,975) in patients with solid tumors. Anticancer Drugs 5: 10-14
-
(1994)
Anticancer Drugs
, vol.5
, pp. 10-14
-
-
Shamdas, G.J.1
Alberts, D.S.2
Modiano, M.3
Wiggins, C.4
Power, J.5
Kasunic, D.A.6
Elfring, G.L.7
Earhart, R.H.8
-
92
-
-
0030720761
-
Nucleic acid-based methods for the detection of cancer
-
Sidransky D (1997) Nucleic acid-based methods for the detection of cancer. Science 278: 1054-1058
-
(1997)
Science
, vol.278
, pp. 1054-1058
-
-
Sidransky, D.1
-
93
-
-
0028180824
-
Cellular pharmacology of novel C8-linked anthramycin-based sequence-selective DNA minor groove cross linking agents
-
Smellie M, Kelland LR, Thurston DE, Souhami RL and Hartley JA (1994) Cellular pharmacology of novel C8-linked anthramycin-based sequence-selective DNA minor groove cross linking agents. Br J Cancer 70: 48-53
-
(1994)
Br J Cancer
, vol.70
, pp. 48-53
-
-
Smellie, M.1
Kelland, L.R.2
Thurston, D.E.3
Souhami, R.L.4
Hartley, J.A.5
-
95
-
-
0028241481
-
Arrays of complementary oligonucleotides for analyzing the hybridization behavior of nucleic acids
-
Southern EM, Casegreen SC, Elder JK, Johnson M, Mir KU, Wang L and Williams JC (1994) Arrays of complementary oligonucleotides for analyzing the hybridization behavior of nucleic acids. Nucleic Acids Res 22: 1368-1373
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 1368-1373
-
-
Southern, E.M.1
Casegreen, S.C.2
Elder, J.K.3
Johnson, M.4
Mir, K.U.5
Wang, L.6
Williams, J.C.7
-
97
-
-
0026348013
-
Site-specific cleavage of human chromosome-4 mediated by triple helix formation
-
Strobel SA, Doucettestamm LA, Riba L, Housman DE and Dervan PB (1991) Site-specific cleavage of human chromosome-4 mediated by triple helix formation. Science 254: 1639-1642
-
(1991)
Science
, vol.254
, pp. 1639-1642
-
-
Strobel, S.A.1
Doucettestamm, L.A.2
Riba, L.3
Housman, D.E.4
Dervan, P.B.5
-
98
-
-
0029762862
-
Sequence specific recognition of DNA by a major and minor groove binding ligand
-
Szewczyk JW, Baird EE and Dervan PB (1996) Sequence specific recognition of DNA by a major and minor groove binding ligand. Angewandte Chem 35: 1487-1489
-
(1996)
Angewandte Chem
, vol.35
, pp. 1487-1489
-
-
Szewczyk, J.W.1
Baird, E.E.2
Dervan, P.B.3
-
99
-
-
33748577758
-
Sequence-specific recognition and modification of double-helical DNA by oligonucleotides
-
Thuong NT and Helene C (1993) Sequence-specific recognition and modification of double-helical DNA by oligonucleotides. Angewandte Chem 32: 666-690
-
(1993)
Angewandte Chem
, vol.32
, pp. 666-690
-
-
Thuong, N.T.1
Helene, C.2
-
100
-
-
0002070325
-
Advances in the study of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour antibiotics
-
Neidle S and Waring MJ (eds) Macmillan Press: London
-
Thurston DE (1993) Advances in the study of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour antibiotics. In: Molecular Aspects of Anticancer Drug DNA Interactions, vol. I, Neidle S and Waring MJ (eds), pp. 54-88. Macmillan Press: London
-
(1993)
Molecular Aspects of Anticancer Drug DNA Interactions
, vol.1
, pp. 54-88
-
-
Thurston, D.E.1
-
101
-
-
0000143411
-
Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines
-
Thurston DE and Bose DS (1994) Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines. Chem Rev 94: 433-465
-
(1994)
Chem Rev
, vol.94
, pp. 433-465
-
-
Thurston, D.E.1
Bose, D.S.2
-
102
-
-
16144362386
-
Synthesis of sequence-selective C8-linked pyrrolo[2,1-c][1,4]benzodiazepine DNA interstrand cross-linking agents
-
Thurston DE, Bose DS, Thompson AS, Howard PW, Leoni A, Croker SJ, Jenkins TC, Neidle S, Hartley JA and Hurley LH (1996) Synthesis of sequence-selective C8-linked pyrrolo[2,1-c][1,4]benzodiazepine DNA interstrand cross-linking agents. J Organ Chem 61: 8141-8147
-
(1996)
J Organ Chem
, vol.61
, pp. 8141-8147
-
-
Thurston, D.E.1
Bose, D.S.2
Thompson, A.S.3
Howard, P.W.4
Leoni, A.5
Croker, S.J.6
Jenkins, T.C.7
Neidle, S.8
Hartley, J.A.9
Hurley, L.H.10
-
103
-
-
0029786013
-
Recognition of DNA by designed ligands at subnanomolar concentrations
-
Trauger JW, Baird EE and Dervan PB (1996) Recognition of DNA by designed ligands at subnanomolar concentrations. Nature 382: 559-561
-
(1996)
Nature
, vol.382
, pp. 559-561
-
-
Trauger, J.W.1
Baird, E.E.2
Dervan, P.B.3
-
104
-
-
0000739713
-
Recognition of 16 base pairs in the minor groove of DNA by a pyrrole-imidazole polyamide dimer
-
Trauger JW, Baird EE and Dervan PB (1998) Recognition of 16 base pairs in the minor groove of DNA by a pyrrole-imidazole polyamide dimer. J Am Chem Soc 120: 3534-3535
-
(1998)
J Am Chem Soc
, vol.120
, pp. 3534-3535
-
-
Trauger, J.W.1
Baird, E.E.2
Dervan, P.B.3
-
105
-
-
0030953342
-
Recognition of seven base pair sequences in the minor groove of DNA by ten ring pyrrole-imidazole polyamide hairpins
-
Turner JM, Baird EE and Dervan PB (1997) Recognition of seven base pair sequences in the minor groove of DNA by ten ring pyrrole-imidazole polyamide hairpins. J Am Chem Soc 119: 7636-7644
-
(1997)
J Am Chem Soc
, vol.119
, pp. 7636-7644
-
-
Turner, J.M.1
Baird, E.E.2
Dervan, P.B.3
-
106
-
-
0031669682
-
Peptide nucleic acids (PNA) and PNA-DNA chimeras: From high binding affinity towards biological function
-
Uhlmann E (1998) Peptide nucleic acids (PNA) and PNA-DNA chimeras: from high binding affinity towards biological function. Biol Chem 379: 1045-1052
-
(1998)
Biol Chem
, vol.379
, pp. 1045-1052
-
-
Uhlmann, E.1
-
108
-
-
0028859271
-
Targeted mutagenests in mammalian cells mediated by intracellular triple-helix formation
-
Wang G, Levy DD, Seidman MM and Glazer PM (1995) Targeted mutagenests in mammalian cells mediated by intracellular triple-helix formation. Mol Cell Biol 15: 1759-1768
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1759-1768
-
-
Wang, G.1
Levy, D.D.2
Seidman, M.M.3
Glazer, P.M.4
-
110
-
-
0032500736
-
Controlling gene expression in living cells through small molecule RNA interactions
-
Werstuck G and Green MR (1998) Controlling gene expression in living cells through small molecule RNA interactions. Science 282: 296-298
-
(1998)
Science
, vol.282
, pp. 296-298
-
-
Werstuck, G.1
Green, M.R.2
-
111
-
-
0031215078
-
On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides
-
White S, Baird EE and Dervan PB (1997) On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides. Chem Biol 4: 569-577
-
(1997)
Chem Biol
, vol.4
, pp. 569-577
-
-
White, S.1
Baird, E.E.2
Dervan, P.B.3
-
112
-
-
0032576722
-
Recognition of the four Watson Crick base pairs in the DNA minor groove by synthetic ligands
-
White S, Szewczyk JW, Turner JM, Baird EE and Dervan PB (1998) Recognition of the four Watson Crick base pairs in the DNA minor groove by synthetic ligands. Nature 391: 468-471
-
(1998)
Nature
, vol.391
, pp. 468-471
-
-
White, S.1
Szewczyk, J.W.2
Turner, J.M.3
Baird, E.E.4
Dervan, P.B.5
-
113
-
-
0032213173
-
Isolation of a fluorophore-specific DNA aptamer with weak redox activity
-
Wilson C and Szostak JW (1998) Isolation of a fluorophore-specific DNA aptamer with weak redox activity. Chem Biol 5: 609-617
-
(1998)
Chem Biol
, vol.5
, pp. 609-617
-
-
Wilson, C.1
Szostak, J.W.2
-
114
-
-
0032569212
-
A library approach to the discovery of small molecules that recognize RNA: Use of a 1,3-hydroxyamine motif as cure
-
Wong CH, Hendrix M, Manning DD, Rosenbohm C and Greenherg WA (1998) A library approach to the discovery of small molecules that recognize RNA: use of a 1,3-hydroxyamine motif as cure. J Am Chem Soc 120: 8319-8327
-
(1998)
J Am Chem Soc
, vol.120
, pp. 8319-8327
-
-
Wong, C.H.1
Hendrix, M.2
Manning, D.D.3
Rosenbohm, C.4
Greenherg, W.A.5
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