Stimulation of the paraventricular nucleus modulates the activity of gut-sensitive neurons in the vagal complex

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 277, Issue 1 40-1, 1999, Pages

  Zhang, Xueguo ^a   Fogel, Ronald ^a   Renehan, William E ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

Author keywords

Dorsal motor nucleus of the vagus; Gastrointestinal neurophysiology; Nucleus of the solitary tract; Vagus

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ELECTROSTIMULATION; ENZYME ACTIVITY; FEEDING; HOMEOSTASIS; HYPOTHALAMUS; HYPOTHESIS; MALE; MOTONEURON NUCLEUS; NONHUMAN; PRIORITY JOURNAL; SOLITARY TRACT NUCLEUS; THALAMUS MIDLINE NUCLEUS; VAGUS NERVE STIMULATION;

EID: 0032797341     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1999.277.1.g79     Document Type: Article

References (37)

1. Azpiroz, F., and J. R. Malagelada. Vagally mediated gastric relaxation-induced by intestinal nutrients in the dog. Am. J. Physiol. 251 (Gastrointest. Liver Physiol. 14): G727-G735, 1986.
2. Banks, D., and M. C. Harris. Activation within dorsal medullary nuclei following stimulation in the hypothalamic paraventricular nucleus in rats. Pflügers Arch. 408: 619-627, 1987.
3. Berk, M. L. Projections of the lateral hypothalamus and bed nucleus of the stria terminalis to the dorsal vagal complex in the pigeon. J. Comp. Neurol. 260: 140-156, 1987.
4. Davison, J. S., and D. Grundy. Modulation of single vagal efferent fibre discharge by gastrointestinal afferents in the rat. J. Physiol. (Lond.) 284: 69-82, 1978.
5. Fogel, R., X. Zhang, and W. E. Renehan. Relationships between the morphology and function of gastric and intestinal distention-sensitive neurons in the dorsal motor nucleus of the vagus. J. Comp. Neurol. 364: 78-91, 1996.
6. Grijalva, C. V., and D. Novin. The role of the hypothalamus and dorsal vagal complex in gastrointestinal function and pathophysiology. Ann. NY Acad. Sci. 597: 207-222, 1990.
7. Grundy, D., A. A. Salih, and T. Scratcherd. Modulation of vagal efferent fibre discharge by mechanoreceptors in the stomach, duodenum and colon of the ferret. J. Physiol. (Lond.) 319: 43-52, 1981.
8. Holstege, G. Some anatomical observations on the projections from the hypothalamus to brainstem and spinal cord: an HRP and autoradiographic tracing study in the cat. J. Comp. Neurol. 260: 98-126, 1987.
9. Kannan, H., and H. Yamashita. Connections of neurons in the region of the nucleus tractus solitarius with the hypothalamic paraventricular nucleus: their possible involvement in neural control of the cardiovascular system in rats. Brain Res. 329: 205-212, 1985.
10. Leslie, R. A., D. J. M. Reynolds, and I. N. C. Lawes. Central connections of the nuclei of the vagus nerve. In: Neuroanatomy and Physiology of Abdominal Vagal Afferents, edited by S. Ritter, R. C. Ritter, and C. D. Barnes, Boca Raton, FL: CRC, 1992, p. 81-98.
11. Miselis, R. R., L. Rinaman, S. M. Altschuler, X. Bao, and R. B. Lynn. Medullary viscerotopic representation of the alimentary canal innervation in rat. In: Brain-Gut Interactions, edited by Y. Taché and D. Wingate. Boca Raton, FL: CRC, 1991, p. 3-21.
12. Nishimura, H., and Y. Oomura. Effects of hypothalamic stimulation on activity of dorsomedial medulla neurons that respond to subdiaphragmatic vagal stimulation. J. Neurophysiol. 58: 655-675, 1987.
13. Petrov, T., T. L. Krukoff, and J. H. Jhamandas. Convergent influence of the central nucleus of the amygdala and the paraventricular hypothalamic nucleus upon brainstem autonomie neurons as revealed by c-fos expression and anatomical tracing. J. Neurosci. Res. 42: 835-845, 1995.
14. Raybould, H. E. Capsaicin-sensitive vagal afferents and CCK in inhibition of gastric motor function-induced by intestinal nutrients. Peptides 12: 1279-1283, 1991.
15. Renehan, W. E., X. Zhang, W. H. Beierwaltes, and R. Fogel. Neurons in the dorsal motor nucleus of the vagus may integrate vagal and spinal information from the GI tract. Am. J. Physiol. 268 (Gastrointest. Liver Physiol. 31): G780-G790, 1995.
16. Rinaman, L., J. P. Card, J. S. Schwaber, and R. R. Miselis. Ultrastructural demonstration of a gastric monosynaptic vagal circuit in the nucleus of the solitary tract in rat. J. Neurosci. 9: 1985-1996, 1989.
17. Ritter, R. C., L. Brenner, and D. P. Yox. Participation of vagal sensory neurons in putative satiety signals from the upper gastrointestinal tract. In: Neuroanatomy and Physiology of Abdominal Vagal Afferents, edited by S. Ritter, R. C. Ritter, and C. D. Barnes. Boca Raton, FL: CRC, 1992, p. 222-248.
18. Ritter, S., and J. S. Taylor. Vagal sensory neurons are required for lipoprivic but not glucoprivic feeding in rats. Am. J. Physiol. 258 (Regulatory Integrative Comp. Physiol. 27): R1395-R1401, 1990.
19. Rogers, R. C., and G. E. Hermann. Vagal afferent stimulation-evoked gastric secretion suppressed by paraventricular nucleus lesion. J. Auton. Nerv. Syst. 13: 191-199, 1985.
20. Rogers, R. C., and G. E. Hermann. Hypothalamic paraventricular nucleus stimulation induced gastric acid secretion and bradycardia suppressed by oxytocin antagonist. Peptides 7: 695-700, 1986.
21. Rogers, R. C., and G. E. Hermann. Oxytocin, oxytocin antagonist, TRH, and hypothalamic paraventricular nucleus effects on gastric motility. Peptides 8: 505-513, 1987.
22. Rogers, R. C., H. Kita, L. L. Butcher, and D. Novin. Afferent projections to the dorsal motor nucleus of the vagus. Brain Res. Bull. 5: 365-373, 1980.
23. Rogers, R. C., D. M. McTigue, and G. E. Hermann. Vagal control of digestion: modulation by central neural and peripheral endocrine factors. Neurosci. Biobehav. Rev. 20: 57-66, 1996.
24. Saper, C. B., A. D. Loewy, L. W. Swanson, and W. M. Cowan. Direct hypothalamo-autonomic connections. Brain Res. 117: 305-312, 1976.
25. Shapiro, R. E., and R. R. Miselis. The central organization of the vagus nerve innervating the stomach of the rat. J. Comp. Neurol. 238: 473-488, 1985.
26. Shiraishi, T. Gastric related properties of rat paraventricular neurons. Brain Res. Bull. 18: 315-323, 1987.
27. Van der Kooy, D., L. Y. Koda, J. F. McGinty, G. R. Gerfen, and F. E. Bloom. The organization of projections from the cortex, amygdala, and hypothalamus to the nucleus of the solitary tract in rat. J. Comp. Neurol. 224: 1-24, 1984.
28. Van Dijk, G., A. E. Bottone, J. H. Strubbe, and A. B. Steffens. Hormonal and metabolic effects of paraventricular hypothalamic administration of neuropeptide Y during rest and feeding. Brain Res. 660: 96-103, 1994.
29. Waldron, J. N. B., S. Ghosh, and P. Zarzecki. Multiple inputs to a population of thalamocortical neurons projecting to cat somatosensory cortex. Exp. Brain Res. 74: 105-115, 1989.
30. Willett, C. J., J. G. Rutherford, D. G. Gwyn, and R. A. Leslie. Projections between the hypothalamus and the dorsal vagal complex in the cat: an HRP and autoradiographic study. Brain Res. Bull. 18: 63-71, 1987.
31. Yoneda, M., and Y. Taché. SMS 201-995 induced stimulation of gastric acid secretion via the dorsal vagal complex and inhibition via the hypothalamus in anaesthetized rats. Br. J. Pharmacol. 116: 2303-2309, 1995.
32. Yoshimatsu, H., A. Niijima, Y. Oomura, and T. Katafuchi. Lateral and ventromedial hypothalamic influences on hepatic autonomie nerve activity in the rat. Brain Res. Bull. 21: 239-244, 1988.
33. Yoshimatsu, H., A. Niijima, Y. Oomura, K. Yamabe, and T. Katafuchi. Effects of hypothalamic lesion on pancreatic autonomic nerve activity in the rat. Brain Res. 303: 147-152, 1984.
34. Zhang, X., R. Fogel, and W. E. Renehan. Physiology and morphology of neurons in the dorsal motor nucleus of the vagus and the nucleus of the solitary tract that are sensitive to distension of the small intestine. J. Comp. Neurol. 323: 432-448, 1992.
35. Zhang, X., R. Fogel, and W. E. Renehan. Relationships between the morphology and function of gastric-and intestine-sensitive neurons in the nucleus of the solitary tract. J. Comp. Neurol. 363: 37-52, 1995.
36. Zhang, X., W. E. Renehan, and R. Fogel. Evidence that nucleus of the solitary tract neurons modulate the activity of vagal motor neurons in vivo (Abstract). In: Fourth International Symposium on Brain-Gut Interactions, 1998.
37. Zhang, X., W. E. Renehan, and R. Fogel. Neurons in the vagal complex of the rat respond to mechanical and chemical stimulation of the GI tract. Am. J. Physiol. 274 (Gastrointest. Liver Physiol. 37): G331-G341, 1998.