α(2A)-adrenoceptors, not I1-imidazoline receptors, mediate the hypotensive effects of rilmenidine and moxonidine in conscious mice. In vivo and in vitro studies

Annals of the New York Academy of Sciences

Volumn 881, Issue , 1999, Pages 287-289

  Zhu, Q M ^a   Lesnick, J D ^a   Jasper, J R ^a   MacLennan, S J ^a   Dillon, M P ^a   Eglen, R M ^a   Blue Jr , D R ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4,5',6,6',7,12B OCTAHYDRO 1',3' DIMETHYL 2H SPIRO[BENZO[B]FURO[2,3 A]QUINOLIZINE 2,4' PYRIMIDINE] 2' ONE; ALPHA 2A ADRENERGIC RECEPTOR; IMIDAZOLINE I1 RECEPTOR; MOXONIDINE; RILMENIDINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIHYPERTENSIVE ACTIVITY; CONFERENCE PAPER; CONTROLLED STUDY; DOG; EMBRYO; HEART RATE; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; SAPHENOUS VEIN; VENOCONSTRICTION;

ANIMALIA; CANIS FAMILIARIS;

EID: 0032797149     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb09371.x     Document Type: Conference Paper

References (5)

1. Yu, A. & W. H. Frishman. 1996. Imidazoline receptor agonist drugs: A new approach to the treatment of systemic hypertension. J. Clin. Pharmacol. 36: 98-111.
2. 2A-AR) mice. Br. J. Pharmacol. 122: 70P.
3. 2-adrenoceptor subtypes. Ann. N.Y. Acad. Sci. 812: 176-177.
4. 35S]GTPγS binding. Biochem. Pharmacol. 55: 1035-1043.
5. 2A subtype. Br. J. Pharmacol. 121: 1721-1729.