Dietary zinc deficiency enhances esophageal cell proliferation and N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumor incidence in C57BL/6 mouse

Cancer Letters

Volumn 143, Issue 1, 1999, Pages 63-69

  Fong, Louise Y Y ^a   Magee, Peter N ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Cell proliferation; Mouse; N nitrosomethylbenzylamine; Tumorigenesis; Zinc deficiency

Indexed keywords

BROXURIDINE; N BENZYL N METHYLNITROSAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INCIDENCE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; ESOPHAGUS TUMOR; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ZINC DEFICIENCY;

ANIMALIA;

EID: 0032796880     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(99)00191-3     Document Type: Article

References (36)

1. Fong L.Y.Y., Sivak A., Newberne P.M. Zinc deficiency and methylbenzylnitrosamine-induced esophageal cancer in rats. J. Natl. Cancer Inst. 61:1978;145-150.
2. van Rensburg S.J., du Bruyn D.B., van Schalkwyk D.J. Promotion of methylbenzyl-nitrosamine-induced esophageal cancer in rats by subclinical zinc deficiency. Nutr. Rep. Int. 22:1980;891-899.
3. Gabrial G.N., Schrager T.F., Newberne P.M. Zinc deficiency, alcohol and retinoid: association with esophageal cancer in rats. J. Natl. Cancer Inst. 68:1982;785-789.
4. Barch D.H., Kuemmerle S., Hollenberg P., Iannaccone P. Esophageal microsomal metabolism of N-nitrosomethylbenzylamine in the zinc-deficient rat. Cancer Res. 44:1984;5629-5633.
5. Fong L.Y.Y., Lee J.S.K., Chan W.C., Newberne P.M. Zinc deficiency and the development of esophageal and forestomach tumors in Sprague-Dawley rats fed precursors of N-nitrosobenzylmethylamine. J. Natl. Cancer Inst. 72:1984;419-425.
6. Fong L.Y.Y., Li J.X., Farber J.L., Magee P.N. Cell proliferation and esophageal carcinogenesis in the zinc-deficient rat. Carcinogenesis. 17:1996;1841-1848.
7. Fong L.Y.Y., Lau K.M., Huebner K., Magee P.N. Induction of esophageal tumors in zinc-deficient rats by single low doses of N-nitrosomethylbenzylamine (NMBA): analysis of cell proliferation, and mutations in H-ras and p53 genesCarcinogenesis. 18:1997;1477-1484.
8. Newberne P.M., Schrager T.S., Broitman S. Esophageal carcinogenesis in the rat: zinc deficiency and alcohol effects on tumor induction. Pathobiology. 65:1997;39-45.
9. Fong L.Y.Y., Pegg A.E., Magee P.N. α-Difluoromethylornithine inhibits N-nitrosomethyl-benzylamine-induced esophageal carcinogenesis in zinc-deficient rats: effects on esophageal cell proliferation and apoptosis. Cancer Res. 58:1998;5380-5388.
10. Follis R.H. Jr. The pathology of zinc deficiency. Prasad A.S. Zinc Metabolism. 1966;129-141 Charles C. Thomas, Springfield, IL.
11. Swenerton H., Hurley L.S. Severe zinc deficiency in male and female rats. J. Nutr. 95:1968;8-18.
12. Oldeleye O.E., Eskelson C.D., Mufti S.I., Watson R.R. Vitamin E protection against nitrosamine-induced esophageal tumor incidence in mice immunocompromised by retroviral infection. Carcinogenesis. 13:1992;1811-1816.
13. Sander J., Schweinsberg F. Tumorinduktion bei Mausen durch N-methylbenzyl-nitrosamin in niedriger Dosierung. Z. Krebsforsch. 19:1973;157-161.
14. Schneider P., Hinrichs S., Zulim R., Towery R., Morris C., Mirvish S.S. Carcinogenesis by methylbenzylnitrosamine near the squamocolumnar junction and methylamylnitrosamine metabolism in the mouse forestomach. Cancer Lett. 102:1996;125-131.
15. Magee P.N., Barnes J.M. Carcinogenic nitroso compounds. Adv. Cancer Res. 10:1967;163-246.
16. Armitage P., Berry G. Statistical Methods in Medical Research. 1987;Blackwell, Oxford.
17. The GLM procedure, SAS/STAT User's Guide, 4th edition, vol. 2, Cary, NC, SAS Institute Inc, 1989.
18. Fong L.Y.Y., Farber J.L., Magee P.N. Zinc replenishment reduces esophageal cell proliferation and N-nitrosomethylbenzylamine (NMBA)-induced esophageal tumor incidence in zinc-deficient rats. Carcinogenesis. 19:1998;1591-1596.
19. Wang L.D., Lipkin M., Qui S.L., Yang G.R., Yang C.S., Newmark H.L. Labeling index and labeling distribution of cells in esophageal epithelium of individuals at increased risk for esophageal cancer in Huixian. China, Cancer Res. 50:1990;2651-2653.
20. Labuc G.E., Archer M.C. Esophageal and hepatic microsomal metabolism of N-nitroso-methylbenzylamine and N-nitrosodimethylamine in the rat. Cancer Res. 42:1982;3181-3186.
21. Fong L.Y.Y., Lin H.J., Lee C.H. Methylation of DNA in target and non-target organs of the rat with methylbenzylnitrosamine and dimethylnitrosamine. Int. J. Cancer. 23:1979;679-682.
22. Hodgson R.M., Wiessler M., Kleihues P. Preferential methylation of target organ DNA by the esophageal carcinogen N-nitrosomethylbenzylnitrosamine. Carcinogenesis. 1:1980;861-866.
23. Autrup H., Stoner G.D. Metabolism of N-nitrosamines by cultured human and rat esophagus. Cancer Res. 42:1982;1307-1311.
24. 6-methylguanine in the esophageal DNA of the rat. Carcinogenesis. 8:1987;1461-1464.
25. 6-alkylguanine-DNA-methyltransferase activities in rat tissues. Cancer Lett. 42:1988;217-223.
26. Sullivan J.F., Jetton M.M., Hahn H.K., Burch E. Enhanced lipid peroxidation in liver microsomes of zinc-deficient rats. Am. J. Clin. Nutr. 33:1980;51-56.
27. Cao G.H., Chen J.D. Effects of dietary zinc on free radical generation, lipid peroxidation, and superoxide dismutase in trained mice. Arch. Biochem. Biophys. 291:1991;147-153.
28. Duerre J.A., Wallwork J.C. Methionine metabolism in isolated perfused livers from rats fed on zinc-deficient and restricted diets. Br. J. Nutr. 56:1986;395-405.
29. Esophageal cancer studies in the Caspian littoral of Iran: results of population studies - a prodrome. J. Natl. Cancer Inst. 59:1977;1127-1138.
30. Yang C.S. Research on esophageal cancer in China. Cancer Res. 40:1980;2633-2644.
31. van Rensburg S.J. Epidemiologic and dietary evidence for a specific nutritional predisposition to esophageal cancer. J. Natl. Cancer Inst. 67:1981;243-251.
32. Lu S.H., Montesano R., Zhang M.S., Feng L., Luo F.J., Chui S.X., Umbenhauer D., Saffhill R., Rajewsky M.F. Relevance of N-nitrosamines to esophageal cancer in China. J. Cellular Physiol. Suppl. 4:1986;51-58.
33. Lu S.H., Chui S.X., Yang W.X., Hu X.N., Guo L.P., Li F.M. Relevance of N-nitrosamines to esophageal cancer in China. 1991;IARC, Lyon. pp. 11-17.
34. Magee P.N. The experimental basis for the role of nitroso compounds in human cancer. Cancer Surveys. 8:1989;207-239.
35. Donaldson D.L., Smith C.C., Walker M.S., Rennert O.W. Tissue zinc and copper levels in diabetic C57BL/KsJ (db/db) mice fed a zinc-deficient: lack of evidence for specific depletion of tissue zinc store. J. Nutr. 118:1988;1502-1508.
36. Shi H.N., Scott M.E., Stevenson M.M., Koski K.G. Energy restriction and zinc deficiency impair the functions of murine T cells and antigen-presenting cells during gastrointestinal nematode infection. J. Nutr. 128:1997;20-27.