Development of a cross-reactive monoclonal antibody to sulfonamide antibiotics: Evidence for structural conformation-selective hapten recognition

Food and Agricultural Immunology

Volumn 11, Issue 2, 1999, Pages 117-134

  Muldoon, Mark T ^a   Font, Ivan A ^a   Beier, Ross C ^a   Holtzapple, Carol K ^a   Young, Colin R ^a   Stanker, Larry H ^a  

^a SOUTHERN PLAINS AGRICULTURAL RESEARCH CENTER   (United States)

Author keywords

Antibiotics; ELISA; Hapten recognition; Molecular modeling; Monoclonal antibody; Protein conjugate; Sulfanitran; Sulfapyridine; Sulfathiazole; Sulfonamides

Indexed keywords

HAPTEN; HYBRIDOMA; MONOCLONAL ANTIBODY; N SULFANILYL 4 AMINOBENZOIC ACID; PROTEIN CONFORMATION; SULFANITRAN; SULFAPYRIDINE; SULFATHIAZOLE;

ANIMALIA; VISCUM ALBUM;

EID: 0032795518     PISSN: 09540105     EISSN: None     Source Type: Journal    
DOI: 10.1080/09540109999807     Document Type: Article

References (18)

1. AERTS, M. M. L., HOGENBOOM, A. C. & BRINKMAN, U. A. Th. (1995) Analytical strategies for the screening of veterinary drugs and their residues in edible products, Journal of Chromatography B: Biomedical Applications, 667, 1-40.
2. 2 torsional terms, Journal of the American Chemical Society, 99, 8127-8134.
3. DIXON-HOLLAND, D. E. & KATZ, S. E. (1988) Competitive direct enzyme-linked immunosorbent assay for detection of sulfamethazine residues in swine and muscle tissue, Journal of the Association of Official Analytical Chemists, 71, 1137-1140.
4. FLEEKER, J. R. & LOVETT, L. J. (1985) Enzyme immunoassay for screening sulfamethazine residues in swine blood, Journal of the Association of Official Analytical Chemists, 68, 172-174.
5. FRANCO, D. A., WEBB, J. & TAYLOR, C. E. (1990) Antibiotic and sulfonamide residues in meat: implications for human health, Journal of Food Protection, 53, 178-185.
6. HOFFMANN, R. (1963) An extended Hückel theory. I. Hydrocarbons, Journal of Chemical Physics, 39, 1397-1412.
7. JACKMAN, R., BROWN, A. J., DELL, A. N. & Everest, S. J. (1993) Production of antisera to 12 sulfonamides and their use in enzyme immunoassays, in Euroresidue II: Conference of Residues of Veterinary Drugs in Foods (HAAGSMA, N., RUITER, A. & CZEDIK-EYEENBERG, P. B., Eds), University of Utrecht, The Netherlands, pp. 391-394.
8. KARUSH, F. (1956) The interaction of purified antibody with optically isomeric haptens. Journal of the American Chemical Society, 78, 5519-5526.
9. KEITH, L. H., CRUMMETT, W., DEEGAN, J., Jr. LIBBY, R. A., TAYLOR, J. K. & WENTLER, G. (1983) Principles of environmental analysis, Analytical Chemistry, 55, 2210-2218.
10. LINDSAY, D. S. & BLAGBURN, B. L. (1995) Antiprotozoan drugs, in Veterinary Pharamacology and Therapeutics (ADAMS, H. R., Ed.), Iowa State University Press, Ames, IA, USA, pp. 955-983.
11. MÄRTLBAUER, E., USLEBER, E., SCHNEIDER, E. & DIETRICH, R. (1994) Immunochemical detection of antibiotics and sulfonamides, Analyst, 119, 2543-2548.
12. PRESSMAN, D., BRYDEN, J. H. & PAULING, L. (1948) The reactions of antiserum homologous to the p-azosuccinanilate ion group, Journal of the American Chemical Society, 70, 1352-1358.
13. RINI, J. M., SCHULZE-GAHMEN, U. & WILSON, I. A. (1992) Structural evidence for induced fit as a mechanism for antibody-antigen recognition, Science, 255, 959-965.
14. SHETH, H. B. & SPORNS, P. (1991) Development of a single ELISA for detection of sulfonamides, Journal of Agricultural and Food Chemistry, 39, 1696-1700.
15. SCHULTZ, P. G. & LERNER, R. A. (1995) From molecular diversity to catalysis: lessons from the immune system, Science, 269, 1835-1842.
16. STANKER, L. H., BRANSCOMB, E., VANDERLAAN, M. & JENSEN, R. H. (1986) Monoclonal antibodies recognizing single amino acid substitutions in hemoglobin, Journal of Immunology, 136, 4174-4180.
17. US DEPARTMENT OF AGRICULTURE (USDA) (1994) Compound Evaluation and Residue Information 1994, Food Safety and Inspection Service, Science and Technology Evaluation Branch, Washington, DC, USA, p. 1.5.
18. WINTERBOTTOM, R. (1940) Sulfanilyl derivatives of pyridine and quinoline amines, Journal of the American Chemical Society, 62, 160-161.