Purification of benzylpenicillin filtered broths by ultrafiltration and effect on solvent extraction

Bioprocess Engineering

Volumn 21, Issue 2, 1999, Pages 157-163

  Nabais, A M A ^a   Cardoso, J P ^a,b  

^a INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^b AtralCipan   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

PENICILLIN G; POLYSULFONE; POLYVINYLIDENE FLUORIDE; SOLVENT;

ARTICLE; DRUG IMPURITY; DRUG PURIFICATION; EXTRACTION; FERMENTATION; FLOCCULATION; MEMBRANE FILTER; MOLECULAR WEIGHT; NONHUMAN; PENICILLIUM CHRYSOGENUM; PHASE SEPARATION; PRIORITY JOURNAL; ULTRAFILTRATION;

EID: 0032795288     PISSN: 0178515X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004490050656     Document Type: Article

References (6)

1. Nabais, A.M.A.; Cardoso, J.P.: Ultrafiltration of fermented broths and solvent extraction of antibiotics. Bioprocess Eng. 13 (1995) 215-221
2. Hersbach, G.J.M.; Van der Beek, C.P.; Van Dijck, P.W.M.: The penicillins: properties, biosynthesis and fermentation. In: Vandamme, E.J. (Ed.): Biotechnology of industrial antibiotics, vol. 22, pp 45-119. New York: Marcel Dekker, Inc. 1984
3. Paterson Candy International, Ltd.: Cleaning, sterilization and preservation procedures, S05 Cleaning 041 (1988)
4. Code of Federal Regulations, CFR. 21 §436.205
5. Bradford, M.M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye. Anal. Biochem. 72 (1976) 248-254
6. Franson, M.A.: Standard methods for the examination of water and wastewater, pp 64-71. New York: American Water Works Association & Water Pollution Control Federation 1976