The in vivo and in vitro comparative nephrotoxicity of cefazolin and gentamicin

Veterinary and Human Toxicology

Volumn 41, Issue 4, 1999, Pages 222-225

  Yilmaz, O ^a   Cabalar, M ^a   Ozbilgin, S ^b  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

^b ULUDAG UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

CEFAZOLIN; GAMMA GLUTAMYLTRANSFERASE; GENTAMICIN; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPATHOLOGY; DRUG INDUCED DISEASE; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CELL CULTURE; KIDNEY NECROSIS; KIDNEY PROXIMAL TUBULE; NEPHROTOXICITY; NONHUMAN; RABBIT;

ANIMALS; CATTLE; CEFAZOLIN; CELLS, CULTURED; CEPHALOSPORINS; GENTAMICINS; KIDNEY; RABBITS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0032794441     PISSN: 01456296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Booth DM: Antimicrobial therapy. Proceedings WSAVA XIX World Congress, Durban-South Africa: 150-155, 1994.
2. Mandell GL, Sande MA: Antimicrobial agents. In Gilman AG et al ed : Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed. Pergamon Press, Singapore: 1088, 1991.
3. Kayaalp O: Medical Pharmacology for Rational Therapy, 6th ed. Feryal Press, Ankara: 667, 1991.
4. Toreci K: Cephalosporins I. History, structure, action mechanism, classification and resistance mechanism. ANKEM Derg 1: 90-99, 1987.
5. Caprile KA: The cephalosporins antimicrobial agents: A comprehensive review. J Vet Pharmacol Ther 11: 1-32, 1988.
6. Freshney RI: Culture of Animal Cells: A Manual of Basic Technique, 2nd ed. Alan R Liss, New York: 245, 1988.
7. Rush GF, Heim RA, Ponsler GD et al: Cephaloridine-induced renal pathological and biochemical changes in female rabbits and isolated proximal tubules in suspension. Toxicol Pathol 20: 155-168, 1992.
8. Haschek WM, Rousseeaux CG: Handbook of Toxicologic Pathology, Academic Press, San Diego: 33-338, 1991.
9. Lash LH, Tokarz JJ, Woods EB: Renal cell type specificity of cephalosporin-induced cytotoxicity in suspensions of isolated proximal tubular and distal tubular cells. Toxicol 94: 97-118, 1994.
10. Demet O, Sanli Y: Toxicology of drugs. In Kaya S ed: Clinical Veterinary Toxicology, Medisan Press, Ankara: 443, 1995.
11. Whiting PH, Thomson AW, Simpson JG: Renal and hepatic function in rats treated with cyclosporin A in combination with gentamicin or cephalosporin antibiotics. Br J Exp Pathol 64: 693-701, 1983.
12. Kato M, Yoshida M, Shimada H et al : Nephrotoxicity of a new cephalosporin, DQ-2556, in rats. Fundam Appl Toxicol 18: 532-539, 1992.
13. Kenneth W, Hinchcliff KW, McGuirk SM et al: Phenolsulfonphthalein pharmacokinetics and renal morphologic changes in adult pony mares with gentamicin-induced nephrotoxicosis. Am J Vet Res 50: 1848-1853, 1989.
14. Mealey KL, Boothe DM: Nephrotoxicosis associated with topical administration of gentamicin in a cat. JAVMA 204: 1919-1921, 1994.
15. Fillastre JP, Laumonier R, Humbert G: Acute renal failure associated with combined gentamicin and cephalothin therapy. Br Med J 2: 396-397, 1973.
16. Hinchcliff KW, Shaftoe S, Dubielzig RR: Gentamicin-induced nephrotoxicosis in a cow. JAVMA 192: 923-925, 1988.
17. Johnson JH, Wolf AM, Johnson TL et al: Gentamicin toxicosis in a North American cougar. JAVMA 203: 854-856, 1993.
18. Maden M: The importance of urinary enzyme activities in dogs with experimentally induced gentamicin nephrotoxicity. Doctoral Thesis, Selcuk Univ Sagl Bil Enst, Konya, 1994.
19. Aytug N, Yilmaz O, Kahraman MM et al: Experimentally induced gentamicin nephrotoxicity in dogs. Proceedings WSAVA XIX World Congress, Durban-South Africa: 773, 1994.
20. Braun JP, Siest G, Rico AG: Uses of gamma-glutamyltransferase in experimental toxicology. Adv Vet Sci Comp Med 31: 151-172, 1987.
21. Greco DS, Turnwald CH, Adams R et al : Urinary γ-glutamyl transpeptidase activity in dogs with gentamicin-induced nephrotoxicity. Am J Vet Res 46: 2332-2335, 1985.
22. Heiene R, Biewenga WJ, Koeman JP: Urinary alkaline phosphatase and gamma-glutamyl transferase as indicators of acute renal damage in dogs. J Small Anim Prac 32: 521-524, 1991.
23. Yavru S, Yavru N: The comparative study on acute renal toxicity of ionic and non-ionic contrast media in cell culture. Selcuk Univ Vet Fak Derg 8: 74-76, 1992.
24. Karademir N: Effect of aflatoxin on tissue cultures. Ankara Univ Vet Fak Derg 38: 284-301, 1991.
25. Alacam T, Omurlu H, Ozkul A et al: Cytotoxicity versus antibacterial activity of some antiseptics in vitro. J Nihon Univ Sch Dent 35: 22-27, 1993.
26. Ayars GH, Altman LC, McManus MM et al: Injurious effect of the eosinophil peroxide-halide system and major basic protein on human nasal epithelium in vitro. Am Rev Respir Dis 140: 125-131, 1989.