New metabolic pathway of (24R)-24,25-dihydroxyvitamin D3: Epimerization of the 3-hydroxy group

Biological and Pharmaceutical Bulletin

Volumn 22, Issue 7, 1999, Pages 767-769

  Higashi, Tatsuya ^a   Kikuchi, Ryuta ^a   Miura, Kanako ^a   Shimada, Kazutake ^a   Hiyamizu, Hiroko ^b   Ooi, Hidenori ^b   Iwabuchi, Yoshiharu ^b   Hatakeyama, Susumi ^b   Kubodera, Noboru ^c  

^a KANAZAWA UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY   (Japan)

^c CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

3 epi 24,25 dihydroxyvitamin D3; Glucuronide; In vivo metabolite; LC MS; Synthesis

Indexed keywords

24,25 DIHYDROXYCOLECALCIFEROL; 3 EPI 24,25 DIHYDROXYCOLECALCIFEROL; DRUG METABOLITE; GLUCURONIDE; HYDROXYL GROUP; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG BILE LEVEL; DRUG CONJUGATION; DRUG METABOLISM; FEMALE; GAS CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; MASS COMMUNICATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STEREOCHEMISTRY;

EID: 0032793836     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.22.767     Document Type: Article

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