Solute absorption from the airways of the isolated rat lung. V. Charge effects on the absorption of copolymers of N(2-hydroxyethyl)-DL-aspartamide with DL-aspartic acid or dimethylaminopropyl-DL-aspartamide

Pharmaceutical Research

Volumn 16, Issue 7, 1999, Pages 1104-1108

  Sun, John Z ^a,c   Byron, Peter R ^a   Rypacek, Frantisek ^b  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^c Research and Development   (United States)

Author keywords

Isolated rat lung; Macromolecules; Polypeptides; Pulmonary absorption; Solute ionization

Indexed keywords

POLYHYDROXYETHYLASPARTAMIDE; POLYHYDROXYETHYLASPARTAMIDE CO ASPARTIC ACID; POLYHYDROXYETHYLASPARTAMIDE CO DIMETHYLAMINOPROPYLASPARTAMIDE; POLYPEPTIDE; UNCLASSIFIED DRUG;

ABSORPTION; ACTIVE TRANSPORT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIFFUSION; DOSE RESPONSE; DRUG ABSORPTION; GEL PERMEATION CHROMATOGRAPHY; HYDRODYNAMICS; IONIZATION; ISOLATED LUNG; LUNG EDEMA; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; SYNTHESIS;

ABSORPTION; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGELS; LUNG; PEPTIDES; PULMONARY ALVEOLI; RATS;

EID: 0032793339     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018904320525     Document Type: Article

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