Apoptotic nuclei within the uterine decidua of first trimester pregnancy arise from CD45 positive leukocytes

American Journal of Reproductive Immunology

Volumn 42, Issue 2, 1999, Pages 88-94

  Hammer, Astrid ^a   Dohr, Gottfried ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Apoptosis; Pregnancy; Reproductive immunology; TUNEL assay; Uterus

Indexed keywords

CD45 ANTIGEN;

APOPTOSIS; CELL NUCLEUS; CONFERENCE PAPER; DECIDUA; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; LEUKOCYTE; PRIORITY JOURNAL;

ANTIGENS, CD45; APOPTOSIS; CELL NUCLEUS; DECIDUA; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IN SITU NICK-END LABELING; JURKAT CELLS; LEUKOCYTES; PREGNANCY; PREGNANCY TRIMESTER, FIRST;

EID: 0032791441     PISSN: 10467408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (46)

1. Beer AE, Billingham RE: The Immunbiology of Mammalian Reproduction, Englewood Cliffs, NJ, Prentice-Hall, 1976.
2. Beer AE, Billingham RE: Host responses to intrauterine, tissue, cellular and fetal allografts. J Reprod Fertil Suppl 1974; 21:59-88.
3. Purcell DFJ, McKenzie IFC, Lublin DM, Johnson PM, Atkinson JP, Oglesby TJ, Deacon NJ: The human cell-surface glycoproteins HuLy-m5, membrane co-factor protein (MCP) of the complement system and trophoblast leukocyte-common (TLX) antigen are CD46. Immunology 1990; 70:155-161.
4. Beer AE, Sio JO: Placenta as an immunological barrier. Biol Reprod 1982; 26:15-27.
5. Hammer A, Hutter H, Dohr G: HLA class I expression on the materno-fetal interface. Am J Reprod Immunol 1997; 38:150-157.
6. King A, Birkby C, Loke YW: Early human decidual cells exhibit NK activity against K the 562 cell line but not against first trimester trophoblast. Cell Immunol 1989; 118:337-344.
7. Bulmer JN, Morrison L, Longfellow M, Ritson A. Pace D: Granulated lymphocytes in human endometrium: histochemical and immunohistochemical studies. Human Reprod 1991; 6:791-798.
8. Loke YW, King A: Human Implantation: Cell Biology and Immunology, Cambridge University Press, Cambridge, UK, 1995.
9. Trauth BC, Klas C, Peters AMJ, Matzuku S, Möller P, Falk W, Debatin KM, Krummer PH: Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 1989; 245:301-305.
10. Yonehara S, Ishii A, Yonehara M: A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor. J Exp Med 1989; 169:1747-1756.
11. Oehm A, Behrmann I, Falk W, Pawlita M, Maier G, Klas C, Li-Weber M, Richards S, Dhein J, Trauth BC, Ponstinol H, Krammer PH: Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor nerve growth factor receptor superfamily: Sequence identity with the Fas antigen. J Biol Chem 1992; 267:10709-10715.
12. Suda T, Nagata S: Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med 1994; 179:873-879.
13. Naeata S, Golstein P: The Fas death factor. Science 1995; 267:1449-1456.
14. Van Parijs L, Abbas AK: Role of Fas-mediated cell death in the regulation of immune responses. Curr Opin Immunol 1996; 8:335-361.
15. Bellgrau D, Gold D, Selawry H, Moore J, Franzusoff A, Duke RC: A role for CD95 ligand in preventing graft rejection. Nature 1995; 377:630-632.
16. Griffith TS, Brunner T, Fletcher SM, Green DR, Ferguson TA: Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 1995; 270:1189-1192.
17. Ferguson TA, Griffith TS: A vision of cell death: Insights into immune privilege. Immunol Rev 1997; 156:167-184.
18. Griffith TS, Ferguson TA: The role of FasL-induced apoptosis in immune privilege. Immunol Today 1997; 18:240-244.
19. Lau HT, Yu M, Fontana A, Stoeckert CJ: Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice. Science 1996; 273:109-112.
20. Xerri L, Devilard E, Hassoun J, Mawas C, Birg F: Fas ligand is not only expressed in immune privileged human organs but is also coexpressed with Fas in various epithelial tissues. J Clin Pathol Mol Pathol 1997; 50:87-91.
21. Bamberger AM, Schulte HM, Thuneke I, Erdmann I, Bamberger CM, Asa SL: Expression of the apoptosis-inducing Fas ligand (FasL) in human first and third trimester placenta and choriocarcinoma cells. J Clin Endocrinol Metab 1997; 82:3173-3175.
22. Hammer A, Blaschitz A, Daxböck C, Walcher W, Dohr G: Fas and Fas-ligand are expressed in the utero-placental unit of first trimester pregnancy. Am J Reprod Immunol 1999; 41:41-51.
23. Stuart PM, Griffith TS, Usui N, Pepose J, Yu X, Ferguson TA: CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. J Clin Invest 1997; 99:396-402.
24. Jones RK, Searle RF, Stewart JA, Turner S, Bulmer JN: Apoptosis, bcl-2 expression, and proliferative activity in human endometrial stroma and endometrial granulated lymphocytes. Biol Reprod 1998; 58:995-1002.
25. Kokawa K, Shikone T, Nakano R: Apoptosis in human chorionic villi and decidua in normal and ectopic pregnancy. Mol Hum Reprod 1998; 4:87-91.
26. Hutter H, Hammer A, Blaschitz A, Hartmann M, Ebbesen P, Dohr G, Ziegler A, Uchanska-Ziegler B: Expression of HLA class I molecules in human first trimester and term placenta trophoblast. Cell Tissue Res 1996; 286:437-444.
27. Kina A, Boocock C, Sharkey AM, Gardner L, Beretta A, Siccardi AG, Loke YW: Evidence for the expression of HLA-C class I mRNA and protein by human first trimester trophoblast. J Immunol 1996; 156:2068-2076.
28. Benichou G, Takizawa PA, Olson CA, McMillan M, Sercarz EE: Donor major histocompatibility complex (MHC) peptides are presented by recipient MHC molecules during graft rejection. J Exp Med 1992; 175:305-308.
29. + natural killer cells with high affinity interleukin 2 receptors in human early pregnancy decidua. Int Immunol 1991; 3:743-750.
30. Saito S, Nishikawa K, Morii T, Narita N, Enomoto M, Ichijo M: Expression of activation antigens CD69, HLA-DR, interleukin-2 receptor-alpha (IL-2R alpha) and IL-2R beta on T cells of human decidua at an early stage of pregnancy. Immunology 1992; 75:710-712.
31. Santis AG, Lopez-Cabrera M, Hamann J, Strauss M, Sanchez-Madrid F: Structure of the gene coding for the human early lymphocyte activation antigen CD69: A C-type lectin receptor evolutionarily related with the gene families of natural killer cell-specific receptors. Eur J Immunol 1994; 24:1692-1697.
32. Ziegler SF, Ramsdell F, Alderson MR: The activation antigen CD69. Stem Cells Deyt 1994; 12:456-465.
33. Eischen CM, Schilling JD, Lynch DH, Krammer PH, Leibson PJ: Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis. J Immunol 1996; 156:2693-2699.
34. Nishimura Y, Ishii A, Kobayashi Y, Yamasaki Y, Yonehara S: Expression and function of mouse Fas antigen on immature and mature T cells. J Immunol 1995; 154:4395-4403.
35. Miyawaki T, Uehara T, Nibu R, Tsuji T, Yachie A, Yonehara S, Taniguchi N: Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood. J Immunol 1992; 149:3753-3758.
36. Lynch DH, Ramsdell F, Alderson MR: Fas and FasL in the homeostatic regulation of immune responses. Immunol Today 1995; 16:569-574.
37. Jiang SP, Vacchio MS: Multiple mechanisms of peripheral T cell tolerance to the fetal "allograft". J Immunol 1998; 160:3086-3090.
38. Takahashi T, Tanaka M, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S: Generalized lympho-proliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994; 76:969-976.
39. Hahne M, Peitsch MC, Irmler M, Schroter M, Lowin B, Rousseau M, Bron C, Renno T, French L, Tschopp J: Characterization of the non-functional Fas ligand of gld mice. Int Immunol 1995; 7:1381-1386.
40. Tafuri A, Alferink J, Moller P, Hammerling GJ, Arnold B: T cell awareness of paternal alloantigens during pregnancy. Science 1995; 270:630-633.
41. Alderson MR, Tough TW, Davis-Smith T, Braddy S, Falk B, Schooley KA, Goodwin RG, Smith CA, Ramsdell F, Lynch DH: Fas ligand mediates activation-induced cell death in human T lymphocytes. J Exp Med 1995; 181:71-77.
42. Bulmer JN, Lunny DP, Hagin SV: Immunohistochemical characterization of stromal leucocytes in nonpregnant human endometrium. Am J Reprod Immunol Microbiol 1988; 17:83-90.
43. Marshall RJ, Jones DB: An immunohistochemical study of lymphoid tissue in human endometrium. Int J Gynecol Pathol 1988; 7:225-235.
44. King A, Wellings V, Gardner L, Loke YW: Immunocytochemical characterization of the unusual large granular lymphocytes in human endometrium throughout the menstrual cycle. Hum Immunol 1989; 24:195-205.
45. Starkey PM, Clover LM, Rees MC: Variation during the menstrual cycle of immune cell populations in human endometrium. Eur J Obstet Gynecol Reprod Biol 1991; 39:203-207.
46. Kokawa K, Shikone T, Nakano R: Apoptosis in the human uterine endometrium during the menstrual cycle. J Clin Endocrinol Metab 1996; 81:4144-4147.