메뉴 건너뛰기




Volumn 92, Issue 2, 1999, Pages 128-137

The pleckstrin homology domain of the Wiskott-Aldrich syndrome protein is involved in the organization of actin cytoskeleton

Author keywords

Actin; Cytoskeleton; Immunodeficiency; Phosphatidylinositol 4,5 bisphosphate (PIP2); Wiskott Aldrich syndrome

Indexed keywords

ACTIN; PLECKSTRIN;

EID: 0032791313     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.1999.4746     Document Type: Article
Times cited : (30)

References (43)
  • 2
    • 0027937223 scopus 로고
    • Isolation of a novel gene mutated in Wiskott-Aldrich syndrome
    • Derry J. M., Ochs H. D., Francke U. Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell. 78:1994;635-644.
    • (1994) Cell , vol.78 , pp. 635-644
    • Derry, J.M.1    Ochs, H.D.2    Francke, U.3
  • 3
    • 0029074506 scopus 로고
    • Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene
    • Kwan S. P., Hagemann T. L., Radtke B. E., Blaese R. M., Rosen F. S. Identification of mutations in the Wiskott-Aldrich syndrome gene and characterization of a polymorphic dinucleotide repeat at DXS6940, adjacent to the disease gene. Proc. Natl. Acad. Sci. USA. 92:1995;4706-4710.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4706-4710
    • Kwan, S.P.1    Hagemann, T.L.2    Radtke, B.E.3    Blaese, R.M.4    Rosen, F.S.5
  • 4
    • 0015291268 scopus 로고
    • Hereditary thrombocytopenia: Relation to Wiskott-Aldrich syndrome with special reference to splenectomy. Report of a family and review of the literature
    • Weiden P. L., Blaese R. M. Hereditary thrombocytopenia: Relation to Wiskott-Aldrich syndrome with special reference to splenectomy. Report of a family and review of the literature. J. Pediatr. 80:1972;226-234.
    • (1972) J. Pediatr. , vol.80 , pp. 226-234
    • Weiden, P.L.1    Blaese, R.M.2
  • 7
    • 0026731846 scopus 로고
    • T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome
    • Molina I. J., Kenney D. M., Rosen F. S., Remold O. D. E. T cell lines characterize events in the pathogenesis of the Wiskott-Aldrich syndrome. J. Exp. Med. 176:1992;867-874.
    • (1992) J. Exp. Med. , vol.176 , pp. 867-874
    • Molina, I.J.1    Kenney, D.M.2    Rosen, F.S.3    Remold, O.D.E.4
  • 8
    • 0022893107 scopus 로고
    • Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome
    • Kenney D., Cairns L., Remold O. D. E., Peterson J., Rosen F. S., Parkman R. Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome. Blood. 68:1986;1329-1332.
    • (1986) Blood , vol.68 , pp. 1329-1332
    • Kenney, D.1    Cairns, L.2    Remold, O.D.E.3    Peterson, J.4    Rosen, F.S.5    Parkman, R.6
  • 9
    • 0029988146 scopus 로고    scopus 로고
    • Defects in Wiskott-Aldrich syndrome blood cells
    • Remold O. D. E., Rosen F. S., Kenney D. M. Defects in Wiskott-Aldrich syndrome blood cells. Blood. 87:1996;2621-2631.
    • (1996) Blood , vol.87 , pp. 2621-2631
    • Remold, O.D.E.1    Rosen, F.S.2    Kenney, D.M.3
  • 10
    • 0029126878 scopus 로고
    • Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains
    • Rivero-Lezcano O. M., Marcilla A., Sameshima J. H., Robbins K. C. Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains. Mol. Cell. Biol. 15:1995;5725-5731.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5725-5731
    • Rivero-Lezcano, O.M.1    Marcilla, A.2    Sameshima, J.H.3    Robbins, K.C.4
  • 11
    • 0030221475 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases
    • Banin S., Truong O., Katz D. R., Waterfield M. D., Brickell P. M., Gout I. Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases. Curr. Biol. 6:1996;981-988.
    • (1996) Curr. Biol. , vol.6 , pp. 981-988
    • Banin, S.1    Truong, O.2    Katz, D.R.3    Waterfield, M.D.4    Brickell, P.M.5    Gout, I.6
  • 13
    • 0030000795 scopus 로고    scopus 로고
    • Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains
    • Finan P. M., Soames C. J., Wilson L., Nelson D. L., Stewart D. M., Truong O., Hsuan J. J., Kellie S. Identification of regions of the Wiskott-Aldrich syndrome protein responsible for association with selected Src homology 3 domains. J. Biol. Chem. 271:1996;26291-26295.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26291-26295
    • Finan, P.M.1    Soames, C.J.2    Wilson, L.3    Nelson, D.L.4    Stewart, D.M.5    Truong, O.6    Hsuan, J.J.7    Kellie, S.8
  • 15
    • 0030006284 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization
    • Symons M., Derry J. M., Karlak B., Jiang S., Lemahieu V., McCormick F., Francke U., Abo A. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell. 84:1996;723-734.
    • (1996) Cell , vol.84 , pp. 723-734
    • Symons, M.1    Derry, J.M.2    Karlak, B.3    Jiang, S.4    Lemahieu, V.5    McCormick, F.6    Francke, U.7    Abo, A.8
  • 16
    • 0029680639 scopus 로고    scopus 로고
    • Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome
    • Aspenstrom P., Lindberg U., Hall A. Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome. Curr. Biol. 6:1996;70-75.
    • (1996) Curr. Biol. , vol.6 , pp. 70-75
    • Aspenstrom, P.1    Lindberg, U.2    Hall, A.3
  • 18
    • 0029815611 scopus 로고    scopus 로고
    • N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases
    • Miki H., Miura K., Takenawa T. N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J. 15:1996;5326-5335.
    • (1996) EMBO J. , vol.15 , pp. 5326-5335
    • Miki, H.1    Miura, K.2    Takenawa, T.3
  • 20
    • 0028786330 scopus 로고
    • The Wiskott-Aldrich syndrome and X-linked congenital thrombocytopenia are caused by mutations of the same gene
    • Zhu Q., Zhang M., Blaese R. M., Derry J. M., Junker A., Francke U., Chen S. H., Ochs H. D. The Wiskott-Aldrich syndrome and X-linked congenital thrombocytopenia are caused by mutations of the same gene. Blood. 86:1995;3797-3804.
    • (1995) Blood , vol.86 , pp. 3797-3804
    • Zhu, Q.1    Zhang, M.2    Blaese, R.M.3    Derry, J.M.4    Junker, A.5    Francke, U.6    Chen, S.H.7    Ochs, H.D.8
  • 22
    • 0030804315 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome/X-linked thrombocytopenia: WASP gene mutations, protein expression, and phenotype
    • Zhu Q., Watanabe C., Liu T., Hollenbaugh D., Blaese R. M., Kanner S. B., Aruffo A., Ochs H. D. Wiskott-Aldrich syndrome/X-linked thrombocytopenia: WASP gene mutations, protein expression, and phenotype. Blood. 90:1997;2680-2689.
    • (1997) Blood , vol.90 , pp. 2680-2689
    • Zhu, Q.1    Watanabe, C.2    Liu, T.3    Hollenbaugh, D.4    Blaese, R.M.5    Kanner, S.B.6    Aruffo, A.7    Ochs, H.D.8
  • 24
    • 0029078212 scopus 로고
    • Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus
    • Kolluri R., Shehabeldin A., Peacocke M., Lamhonwah A. M., Teichert-Kuliszewska K., Weissman S. M., Siminovitch K. A. Identification of WASP mutations in patients with Wiskott-Aldrich syndrome and isolated thrombocytopenia reveals allelic heterogeneity at the WAS locus. Hum. Mol. Genet. 4:1995;1119-1126.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 1119-1126
    • Kolluri, R.1    Shehabeldin, A.2    Peacocke, M.3    Lamhonwah, A.M.4    Teichert-Kuliszewska, K.5    Weissman, S.M.6    Siminovitch, K.A.7
  • 25
    • 0029999252 scopus 로고    scopus 로고
    • Wiskott-Aldrich syndrome: No strict genotype-phenotype correlations but clustering of missense mutations in the amino-terminal part of the WASP gene product
    • Schindelhauer D., Weiss M., Hellebrand H., Golla A., Hergersberg M., Seger R., Belohradsky B. H., Meindl A. Wiskott-Aldrich syndrome: No strict genotype-phenotype correlations but clustering of missense mutations in the amino-terminal part of the WASP gene product. Hum. Genet. 98:1996;68-76.
    • (1996) Hum. Genet. , vol.98 , pp. 68-76
    • Schindelhauer, D.1    Weiss, M.2    Hellebrand, H.3    Golla, A.4    Hergersberg, M.5    Seger, R.6    Belohradsky, B.H.7    Meindl, A.8
  • 26
    • 0029836850 scopus 로고    scopus 로고
    • Isolated X-linked thrombocytopenia in two unrelated families is associated with point mutations in the Wiskott-Aldrich syndrome protein gene
    • de Saint Basile G., Lagelouse R. D., Lambert N., Schwarz K., Le Mareck B., Odent S., Schlegel N., Fischer A. Isolated X-linked thrombocytopenia in two unrelated families is associated with point mutations in the Wiskott-Aldrich syndrome protein gene. J. Pediatr. 129:1996;56-62.
    • (1996) J. Pediatr. , vol.129 , pp. 56-62
    • De Saint Basile, G.1    Lagelouse, R.D.2    Lambert, N.3    Schwarz, K.4    Le Mareck, B.5    Odent, S.6    Schlegel, N.7    Fischer, A.8
  • 27
    • 0028850286 scopus 로고
    • High prevalence of nonsense, frame shift, and splice-site mutations in 16 patients with full-blown Wiskott-Aldrich syndrome
    • Wengler G. S., Notarangelo L. D., Berardelli S., Pollonni G., Mella P., Fasth A., Ugazio A. G., Parolini O. High prevalence of nonsense, frame shift, and splice-site mutations in 16 patients with full-blown Wiskott-Aldrich syndrome. Blood. 86:1995;3648-3654.
    • (1995) Blood , vol.86 , pp. 3648-3654
    • Wengler, G.S.1    Notarangelo, L.D.2    Berardelli, S.3    Pollonni, G.4    Mella, P.5    Fasth, A.6    Ugazio, A.G.7    Parolini, O.8
  • 29
    • 0028880534 scopus 로고
    • Scanning of the Wiskott-Aldrich syndrome (WAS) gene: Identification of 18 novel alterations including a possible mutation hotspot at Arg86 resulting in thrombocytopenia, a mild WAS phenotype
    • Kwan S. P., Hagemann T. L., Blaese R. M., Knutsen A., Rosen F. S. Scanning of the Wiskott-Aldrich syndrome (WAS) gene: Identification of 18 novel alterations including a possible mutation hotspot at Arg86 resulting in thrombocytopenia, a mild WAS phenotype. Hum. Mol. Genet. 4:1995;1995-1998.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 1995-1998
    • Kwan, S.P.1    Hagemann, T.L.2    Blaese, R.M.3    Knutsen, A.4    Rosen, F.S.5
  • 31
    • 0028021882 scopus 로고
    • Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
    • Harlan J. E., Hajduk P. J., Yoon H. S., Fesik S. W. Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature. 371:1994;168-170.
    • (1994) Nature , vol.371 , pp. 168-170
    • Harlan, J.E.1    Hajduk, P.J.2    Yoon, H.S.3    Fesik, S.W.4
  • 32
    • 0029087181 scopus 로고
    • Structural characterization of the interaction between a pleckstrin homology domain and phosphatidylinositol 4,5-bisphosphate
    • Harlan J. E., Yoon H. S., Hajduk P. J., Fesik S. W. Structural characterization of the interaction between a pleckstrin homology domain and phosphatidylinositol 4,5-bisphosphate. Biochemistry. 34:1995;9859-9864.
    • (1995) Biochemistry , vol.34 , pp. 9859-9864
    • Harlan, J.E.1    Yoon, H.S.2    Hajduk, P.J.3    Fesik, S.W.4
  • 33
    • 0028874438 scopus 로고
    • Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain
    • Lemmon M. A., Ferguson K. M., O'Brien R., Sigler P. B., Schlessinger J. Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain. Proc. Natl. Acad. Sci. USA. 92:1995;10472-10476.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10472-10476
    • Lemmon, M.A.1    Ferguson, K.M.2    O'Brien, R.3    Sigler, P.B.4    Schlessinger, J.5
  • 34
    • 0028787055 scopus 로고
    • The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes
    • Garcia P., Gupta R., Shah S., Morris A. J., Rudge S. A., Scarlata S., Petrova V., McLaughlin S., Rebecchi M. J. The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes. Biochemistry. 34:1995;16228-16234.
    • (1995) Biochemistry , vol.34 , pp. 16228-16234
    • Garcia, P.1    Gupta, R.2    Shah, S.3    Morris, A.J.4    Rudge, S.A.5    Scarlata, S.6    Petrova, V.7    McLaughlin, S.8    Rebecchi, M.J.9
  • 35
    • 0029939448 scopus 로고    scopus 로고
    • PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface
    • Lemmon M. A., Ferguson K. M., Schlessinger J. PH domains: Diverse sequences with a common fold recruit signaling molecules to the cell surface. Cell. 85:1996;621-624.
    • (1996) Cell , vol.85 , pp. 621-624
    • Lemmon, M.A.1    Ferguson, K.M.2    Schlessinger, J.3
  • 36
    • 0029617615 scopus 로고
    • Structure of the high affinity complex of inositol trisphos-phate with a phospholipase C pleckstrin homology domain
    • Ferguson K. M., Lemmon M. A., Schlessinger J., Sigler P. B. Structure of the high affinity complex of inositol trisphos-phate with a phospholipase C pleckstrin homology domain. Cell. 83:1995;1037-1046.
    • (1995) Cell , vol.83 , pp. 1037-1046
    • Ferguson, K.M.1    Lemmon, M.A.2    Schlessinger, J.3    Sigler, P.B.4
  • 38
    • 0028564915 scopus 로고
    • The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C
    • Yao L., Kawakami Y., Kawakami T. The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C. Proc. Natl. Acad. Sci. USA. 91:1994;9175-9179.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9175-9179
    • Yao, L.1    Kawakami, Y.2    Kawakami, T.3
  • 39
    • 0028246440 scopus 로고
    • Binding of G protein beta gamma-subunits to pleckstrin homology domains
    • Touhara K., Inglese J., Pitcher J. A., Shaw G., Lefkowitz R. J. Binding of G protein beta gamma-subunits to pleckstrin homology domains. J. Biol. Chem. 269:1994;10217-10220.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10217-10220
    • Touhara, K.1    Inglese, J.2    Pitcher, J.A.3    Shaw, G.4    Lefkowitz, R.J.5
  • 41
    • 0027299745 scopus 로고
    • On the crawling of animal cells
    • Stossel T. P. On the crawling of animal cells. Science. 260:1993;1086-1094.
    • (1993) Science , vol.260 , pp. 1086-1094
    • Stossel, T.P.1
  • 42
    • 0032518666 scopus 로고    scopus 로고
    • Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting
    • Falasca M., Logan S. K., Lehto V. P., Baccante G., Lemmon M. A., Schlessinger J. Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting. EMBO J. 17:1998;414-422.
    • (1998) EMBO J. , vol.17 , pp. 414-422
    • Falasca, M.1    Logan, S.K.2    Lehto, V.P.3    Baccante, G.4    Lemmon, M.A.5    Schlessinger, J.6
  • 43
    • 0030826662 scopus 로고    scopus 로고
    • Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase
    • August A., Sadra A., Dupont B., Hanafusa H. Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase. Proc. Natl. Acad. Sci. USA. 94:1997;11227-11232.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11227-11232
    • August, A.1    Sadra, A.2    Dupont, B.3    Hanafusa, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.