Systemic and mucosal immune responses of pigs to parenteral immunization with a pepsin-digested Serpulina hyodysenteriae bacterin

Veterinary Immunology and Immunopathology

Volumn 69, Issue 1, 1999, Pages 75-87

  Waters, W R ^a   Sacco, R E ^b   Dorn, A D ^a   Hontecillas, R ^a   Zuckermann, F A ^c   Wannemuehler, M J ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

CD8; Colitis; IL 10; Interferon ; Porcine cellular immunity; Serpulina hyodysenteriae

Indexed keywords

ANTIBODY; BACTERIAL VACCINE; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRACHYSPIRA; CELLULAR IMMUNITY; COLITIS; CONTROLLED STUDY; DYSENTERY; LYMPH NODE; LYMPHOCYTE SUBPOPULATION; NONHUMAN; VACCINATION;

BRACHYSPIRA HYODYSENTERIAE; SUIDAE; SUS SCROFA;

EID: 0032790235     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(99)00043-4     Document Type: Article

References (15)

1. Bailey M., Hall L., Bland P.W., Stokes C.R. Production of cytokines by lymphocytes from spleen, mesenteric lymph node, and intestinal lamina propria of pigs. Immunol. 82:1994;577-583.
2. Brown W.C., Woods V.M., Chitko-Mckown C.G., Hash S.M., Rice-Ficht A.C. Interleukin-10 is expressed by bovine type 1 helper, type 2 helper, and unrestricted parasite-specific T-cell clones and inhibits proliferation of all three subsets in an accessory-cell-dependent manner. Infect. Immun. 62:1994;4697-4708.
3. Galvin, J.E., 1995. Pathogenesis of swine dysentery: The role of luminal antigens in the activation of mucosal T lymphocytes. Ph.D. dissertation, Iowa State University.
4. Husmann R.J., Brandt J., Martin S., Zuckermann F.A. A modified live pseudorabies virus vaccine induces higher levels of cell-mediated immunity and protection than inactivated vaccine. Conf. Res. Workers Anim. Dis. 77:1996;117.
5. Joens L.A., Harris D.L., Baum D.H. Immunity to swine dysentery in recovered pigs. Am. J. Vet. Res. 40:1979;1352-1354.
6. Kunkle R.A., Kinyon J.M. Improved selective medium for the isolation of Treponema hyodysenteriae. J. Clin. Microbiol. 26:1988;2357-2360.
7. Mansfield L.S., Urban J.J. The pathogenesis of necrotic proliferative colitis in swine is linked to whipworm induced suppression of mucosal immunity to resident bacteria. Vet. Immunol. Immunopathol. 50:1996;1-17.
8. Mosmann T.R., Coffman R.L. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann. Rev. Immunol. 7:1989;145-173.
9. Nibbelink S.K., Wannemuehler M.J. An enhanced murine model for studies of Serpulina (Treponema) hyodysenteriae pathogenesis. Infect. Immun. 60:1992;3433-3436.
10. Olson L.D., Dayalu K.I., Schlink G.T. Exacerbated onset of dysentery in swine vaccinated with inactivated adjuvanted Serpulina hyodysenteriae. Am. J. Vet. Res. 55:1994;67-71.
11. + dual expressing T-cells. Vet. Immunol. Immunopathol. 43:1994;53-62.
12. Stokes C.R., Haverson K., Bailey M. Antigen presenting cells in the porcine gut. Vet. Immunol. Immunopathol. 54:1996;171-177.
13. VanCott J.L., Brim T.A., Lunney J.K., Saif L.J. Contribution of antibody-secreting cells induced in mucosal lymphoid tissues of pigs inoculated with respiratory or enteric strains of coronavirus to immunity against enteric coronavirus challenge. J. Immunol. 152:1994;3980-3990.
14. Zuckermann, F.A., Husmann, R.J., 1996., The human and swine CD4/CD8 double positive T lymphocyte. In: Tumbleson, M.E., Schook, L.B. (Ed.), Advances in Swine Biomedical Research, vol. 1 Plenum Press, New York, pp. 331-344.
15. Zuckermann F.A., Husmann R.J., Schwartz R., Brandt J., Mateu de Antonio E., Martin S. Interleukin-12 enhances the virus-specific interferon gamma response of pigs to an inactivated pseudorabies virus vaccine. Vet. Immunol. Immunopathol. 63:1998;57-67.