The combined effects of sevoflurane and remifentanil on central respiratory activity and nociceptive cardiovascular responses in anesthetized rabbits

Anesthesia and Analgesia

Volumn 89, Issue 2, 1999, Pages 453-461

  Ma, Daqing ^a   Chakrabarti, Mihir K ^a   Whitwam, James G ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

REMIFENTANIL; SEVOFLURANE;

ANIMAL EXPERIMENT; ARTICLE; BREATHING; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; DRUG MIXTURE; DRUG POTENTIATION; GENERAL ANESTHESIA; INHALATIONAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MEAN ARTERIAL PRESSURE; NOCICEPTION; NONHUMAN; PHRENIC NERVE; PRESSOR RESPONSE; PRIORITY JOURNAL; RABBIT;

ACTION POTENTIALS; ANESTHESIA; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; BLOOD PRESSURE; DEPRESSION, CHEMICAL; DRUG INTERACTIONS; ELECTRIC STIMULATION; EVOKED POTENTIALS; HEART RATE; HEMODYNAMIC PROCESSES; METHYL ETHERS; PAIN; PHRENIC NERVE; PIPERIDINES; RABBITS; RESPIRATION;

EID: 0032787254     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199908000-00039     Document Type: Article

References (39)

1. Roy WL, Edelist G, Gilbert B. Myocardial ischemia during non-cardiac surgical procedures in patients with coronary-artery disease. Anesthesiology 1979;51:393-7.
2. Rao TL, Jacobs KH, EL-Etr AA. Reinfarction following anesthesia in patients with myocardial infraction. Anesthesiology 1983; 59:499-505.
3. Roizen MF, Saidman LJ. Redefining anesthetic management: goals for the anesthesiologist. Anesthesiology 1994;80:251-2.
4. Magano DT, Layung EL, Wallace A, Tateo I. Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery. N Engl J Med 1996;335:1713-20.
5. Roizen MF, Horrigan RW, Frazer BM. Anesthetic doses blocking adrenergic (stress) and cardiovascular responses to incision-MAC BAR. Anesthesiology 1981;54:390-8.
6. Zbinden AM, Petersen-Felix S, Thomson DA. Anesthetic depth defined using multiple noxious stimuli during isoflurane/ oxygen anesthesia. II. Hemodynamic responses. Anesthesiology 1994;80:261-7.
7. Daniel M, Weiskopf RB, Noorani M, Eger EI II. Fentanyl augments the blockade of the sympathetic response to incision (MAC-BAR) produced by desflurane and isoflurane: desflurane and isoflurane MAC-BAR without and with fentanyl. Anesthesiology 1998;88:43-9.
8. Hoke JF, Shlugman D, Dershwitz M, et al. Pharmacokinetics and pharmacodynamics of remifentanil in persons with renal failure compared with healthy volunteers. Anesthesiology 1997; 87:533-41.
9. Glass PS, Hardman D, Kamiyama Y, et al. Preliminary pharmacokinetics and pharmacodynamics of an ultra-shorting-acting opioid: remifentanil (GI87084B). Anesth Analg 1993;77:1031-40.
10. Blumrich W, Meyer K, Hans FJ, et al. Interactions of remifentanil and sevoflurane in spontaneously breathing patients [abstract]. Anesthesiology 1997;87:A7.
11. Ma D, Sapsed-Byrne SM, Chakrabarti MK, et al. Synergism between sevoflurane and intravenous fentanyl on AΔ and C somatosympathetic reflexes in dogs. Anesth Analg 1998;87: 211-6.
12. Ma D, Sapsed-Byrne SM, Chakrabarti MK, Whitwam JG. Synergistic antinociceptive interaction between sevoflurane and intrathecal fentanyl in dogs. Br J Anaesth 1998;80:800-6.
13. Hoffman WE, Cunningham F, James MK, et al. Effects of remifentanil, a new short-acting opioid, on cerebral blood flow, brain electrical activity, and intracranial pressure in dogs anesthetized with isoflurane and nitrous oxide. Anesthesiology 1993;79:107-13.
14. Berenbaum MC. What is synergy? Pharmacol Rev 1989;41: 93-141.
15. Evanich MJ, Franco MJ, Lourenco RV. Force output of the diaphragm as a function of phrenic nerve firing rate and lung volume. J Appl Physiol 1973;35:208-12.
16. McCrimmon DR, Lalley PM. Inhibition of respiratory neural discharges by clonidine and 5-hydroxytryptophan. J Pharmacol Exp Ther 1982;222:771-7.
17. Stuth EA, Tonkovic-Capin M, Kampine JP, et al. Dose-dependent effects of halothane on the carbon dioxide responses of expiratory and inspiratory bulbospinal neurons and the phrenic nerve activities in dogs. Anesthesiology 1994;81: 1470-83.
18. 2 responses of expiratory medullary neurons and the phrenic nerve activities in dogs. Anesthesiology 1992;76:763-74.
19. Morray JP, Nobel R, Bennet L, Hanson MA. The effect of halothane on phrenic and chemoreceptor responses to hypoxia in anesthetized kittens. Anesth Analg 1996;83:329-35.
20. Green WB Jr. The ventilatory effects of sevoflurane. Anesth Analg 1995;81:S23-6.
21. Martin WR. Pharmacology of opioids. Pharmacol Rev 1983;35: 283-323.
22. Sato A, Schmidt RF. Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics. Physiol Rev 1973; 53:916-47.
23. Samso E, Farber NE, Kampine JP, Schmeling WT. The effects of halothane on pressor and depressor responses elicited via the somatosympathetic reflex: a potential antinociceptive action. Anesth Analg 1994;79:971-9.
24. Ganjoo P, Farber NE, Schwabe D, et al. Desflurane attenuates the somatosympathetic reflex in rats. Anesth Analg 1996;83: 55-61.
25. Collins JG, Kendig JJ, Mason P. Anesthetic action within the spinal cord: contributions to the state of general anesthesia. Trends Neurosci 1995;18:549-53.
26. Eger EI II, Koblin DD, Harris RA, et al. Hypothesis: inhaled anesthetics produce immobility and amnesia by different mechanisms at different sites. Anesth Analg 1997;84:915-8.
27. Farber NE, Samso E, Kampine JP, Schmeling WT. The effects of halothane on cardiovascular responses in the neuraxis of cats: influence of background anesthetic state. Anesthesiology 1995; 82:153-65.
28. Bosnjak ZJ, Seagard JL, Wu A, Kampine JP. The effects of halothane on sympathetic ganglionic transmission. Anesthesiology 1982;57:473-9.
29. Boban N, McCallum B, Schedewie HK, et al. Direct comparative effects of isoflurane and desflurane on sympathetic ganglionic transmission. Anesth Analg 1995;80:127-34.
30. Nagayama T, Meguro K, Kurosawa M, et al. Effect of different concentrations of an inhaled anesthetic agent, sevoflurane, on sympatho-adrenal medullary function in rat. Masui 1993;42: 1754-62.
31. Ma D, Wang C, Pac Soo CK, et al. The effect of sevoflurane on spontaneous sympathetic activity, AΔ and C somatosympathetic reflexes, and associated hemodynamic changes in dogs. Anesth Analg 1998;86:1079-83.
32. Wynands JE, Townsend GE, Wong P, et al. Blood pressure response and plasma fentanyl concentrations during high- and very high-dose fentanyl anesthesia for coronary artery surgery. Anesth Analg 1983;62:661-5.
33. Lang E, Kapila A, Shlugman D, et al. Reduction of isoflurane minimal alveolar concentration by remifentanil. Anesthesiology 1996;85:721-8.
34. Ma D, Sapsed-Byrne SM, Chakrabarti MK, Whitwam JG. Effect of sevoflurane on spontaneous sympathetic activity and baroreflexes in rabbits. Br J Anaesth 1998;80:68-72.
35. Kapila A, Glass PS, Jacobs JR, et al. Measured context-sensitive half-times of remifentanil and alfentanil. Anesthesiology 1995; 83:968-75.
36. Soma LR. Anesthetic and analgesic considerations in the experimental animal. Ann N Y Acad Sci 1983;406:32-47.
37. Haxhiu MA, Deal EC Jr, Trivedi RD, et al. Tracheal and phrenic responses to neurotensin applied to ventral medulla. Am J Physiol 1988;255:R780-6.
38. Gautier H, Bonora M. Effects of hypoxia and respiratory stimulants in conscious intact and carotid denervated cats. Bull Eur Physiopathol Respir 1982;18:565-82.
39. Grundy EM, Chakrabarti MK, Whitwam JG. Efferent phrenic nerve activity during induced changes in arterial pressure. Br J Anaesth 1986;58:1414-21.