Serotonin-stimulated increase in cytosolic Ca2+ in cultured rat heart endothelial cells

European Journal of Pharmacology

Volumn 384, Issue 1, 1999, Pages 53-60

  Lee, Hong Zin ^a   Wu, Chun Hsiung ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

5 Hydroxytryptamine (5 HT), serotonin; Ca2+ channel blocker; Ca2+ concentration, intracellular; Endothelial cell, rat; Permeability; Phospholipase C inhibitor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM CHANNEL; CALCIUM ION; CYPROHEPTADINE; NEOMYCIN; PHOSPHOLIPASE C INHIBITOR; SEROTONIN; SEROTONIN 2 ANTAGONIST; THROMBIN; VERAPAMIL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; DEPLETION; DOSE TIME EFFECT RELATION; DRUG ANTAGONISM; ENDOTHELIUM CELL; HEART; MEMBRANE PERMEABILITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CATTLE; CELL MEMBRANE PERMEABILITY; CELLS, CULTURED; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ESTRENES; FETAL BLOOD; HEART VENTRICLES; L-LACTATE DEHYDROGENASE; NEOMYCIN; NICKEL; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C; PYRROLIDINONES; RATS; SEROTONIN; TIME FACTORS; VERAPAMIL;

EID: 0032784791     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00672-X     Document Type: Article

References (27)

1. 2+ permeant nonspecific cation channel in hepatic endothelial cells. Biochem. Biophys. Res. Commun. 186:1992;1560-1566.
2. Buchan K.W., Martin W. Modulation of barrier function of bovine aortic and pulmonary artery endothelial cells: Dissociation from cytosolic calcium content. Br. J. Pharmacol. 107:1992;932-938.
3. Carney D.H., Scott D.L., Gordon E.A., Labelle E.F. Phosphoinositides in mitogenesis: neomycin inhibits thrombin-stimulated phosphoinositide turnover and initiation of cell proliferation. Cell. 42:1985;479-488.
4. Chandler D., Meusel G., Schumaker E., Stapleton C. FMLP-induced release from neutrophils: a role for intracellular calcium. Am. J. Physiol. 245:1983;C196-C202.
5. Curry F.E. Modulation of venular microvessel permeability by calcium influx into endothelial cells. FASEB. 6:1992;2456-2466.
6. 2+ mobilization, barrier dysfunction, prostaglandin synthesis, and platelet-derived growth factor mRNA expression in cultured endothelium. J. Cell. Physiol. 156:1993;541-549.
7. Garcia J.G.N., Davis H.W., Patterson C.E. Regulation of endothelial cell gap formation and barrier dysfunction: role of myosin light chain phosphorylation. J. Cell. Physiol. 163:1995;510-522.
8. Goligorsky M.S., Menton D.N., Laszlo A., Lum H. Nature of thrombin-induced sustained increase in cytosolic calcium concentration in cultured endothelial cells. J. Biol. Chem. 264:1989;16771-16775.
9. Himmel H.M., Whorton A.R., Strauss H.C. Intracellular calcium, currents, and stimulus-response coupling in endothelial cells. Hypertension. 21:1993;112-127.
10. Jaffe E.A., Nachman R.L., Becker C.G., Minick C.R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52:1973;2745-2756.
11. Lee H.Z. Inhibitory effect of 2-phenyl-4-quinolone on serotonin-mediated changes in the morphology and permeability of endothelial monolayers. Eur. J. Pharmacol. 335:1997;245-254.
12. Lee H.Z., Lin W.C., Yeh F.T., Wu C.H. Decreased protein kinase C activation mediates inhibitory effect of norathyriol on serotonin-mediated endothelial permeability. Eur. J. Pharmacol. 353:1998;303-313.
13. Lin A.Y., Rui Y.C. Platelet-activating factor induced calcium mobilization and phosphoinositide metabolism in cultured bovine cerebral microvascular endothelial cells. Biochim. Biophys. Acta. 1224:1994;323-328.
14. 2+ and inositol polyphosphates. Am. J. Physiol. 263:1992;L219-L225.
15. Majno G., Palade C.E., Schhoeft G.I. Studies on inflammation: II. The site of action of histamine and serotonin along the vascular tree: a topographic study. J. Biophys. Biochem. Cytol. 11:1961;607-626.
16. 2+ dynamics in endothelial cells. Am. J. Physiol. 253:1987;C588-C598.
17. Patterson C.E., Davis H.W., Schaphorst K.L., Garcia J.G.N. Mechanisms of cholera toxin prevention of thrombin- and PMA-induced endothelial cell barrier dysfunction. Microvasc. Res. 48:1994;212-235.
18. Rotrosen D., Gallin J.I. Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces F-actin, and promotes albumin diffusion across cultured endothelial monolayers. J. Cell Biol. 103:1986;2379-2387.
19. Schaeffer R.C. Jr., Gong F., Bitrick M.S., Smith T.L. Thrombin and bradykinin initiate discrete endothelial solute permeability mechanisms. Am. J. Physiol. 264:1993;H1798-H1809.
20. 2+ signaling mechanisms of vascular endothelial cells and their role in oxidant-induced endothelial cell dysfunction. Am. J. Physiol. 262:1992;H1617-H1630.
21. Schilling W.P., Ritchie A.K., Navarro L.T., Eskin S.G. Bradykinin-stimulated calcium influx in cultured bovine aortic endothelial cells. Am. J. Physiol. 255:1988;H219-H227.
22. Schilling W.P., Rajan L., Meszaros J.G., Elliott S.J. Effect of U73122, an inhibitor of phospholipase C, on signal transduction in vascular endothelial cells. FASEB J. 5:1991;A697.
23. Singer H.A., Peach M.J. Calcium- and endothelial-mediated vascular smooth muscle relaxation in rabbit aorta. Hypertension (Dallas). 4(Suppl. II):1982;19-25.
24. Stanimirovic D., Morley P., Ball R., Hamel E., Mealing G., Durkin J.P. Angiotensin II-induced fluid phase endocytosis in human cerebromicrovascular endothelial cells is regulated by the inositol-phosphate signaling pathway. J. Cell. Physiol. 169:1996;455-467.
25. 77 and vimentin and enhances albumin permeability across cultured bovine pulmonary artery endothelial cell monolayers. J. Cell. Physiol. 153:1992;62-75.
26. Svensjo E., Grega G.J. Evidence for endothelial cell-mediated regulation of macromolecular permeability by postcapillary venules. Fed. Proc. 45:1986;89-95.
27. Xia P., Aiello L.P., Ishii H., Jiang Z.Y., Park D.J., Robinson G.S., Takagi H., Newsome W.P., Jirousek M.R., King G.L. Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth. J. Clin. Invest. 98:1996;2018-2026.