The morbidity and mortality of pediatric splenectomy: Does prophylaxis make a difference?

Journal of Pediatric Surgery

Volumn 34, Issue 7, 1999, Pages 1064-1067

  Jugenburg, Martin ^a   Haddock, Graham ^a   Freedman, Melvin H ^a   Ford Jones, Lee ^a   Ein, Sigmund H ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Immunization; Sepsis; Splenectomy

Indexed keywords

CHILD; CONFERENCE PAPER; HUMAN; IMMUNIZATION; INFECTION PREVENTION; INFECTION RISK; MAJOR CLINICAL STUDY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SEPSIS; SPLENECTOMY; SURGICAL RISK;

EID: 0032784076     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3468(99)90565-1     Document Type: Conference Paper

References (22)

1. King H, Shumacker HB Jr: Splenic studies: Susceptibility to infection after splenectomy performed in infancy. Ann Surg 136:239-242, 1952
2. Cullingford GL, Watkins DN, Watts ADJ, et al: Severe late post-splenectomy infection. Br J Surg 78:716-721, 1991
3. Ein SH, Shandling B, Simpson JS, et al: The morbidity and mortality in splenectomy in childhood. Ann Surg 185:307-310, 1977
4. Working Party of the British Committee for Standards in Haematology Clinical Haematology Task Force: Guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen. BMJ 312:430-434, 1996
5. Ellinson EC, Fabri PJ: Complications of splenectomy. Etiology, prevention, and management. Surg Clin North Am 63:1313-30, 1983
6. Diamond LK: Splenectomy in childhood and the hazzard of overwhelming infection. Pediatrics 43:886-889, 1969
7. Shaw JHF, Print CG: Postsplenectomy sepsis. Br J Surg 76:1074-1081, 1989
8. Hays DM, Tumberg DL, Chen TT, et al: Postsplenectomy sepsis and other complications following staging laparotomy for Hodgkin's disease in children. J Pediatr Surg 21:628-632, 1986
9. Horowitz J, Smith JL, Weber TK, et al: Postoperative complications after splenectomy for hematologic malignancies. Ann Surg 223:290-296, 1996
10. Cole JT, Flaum MA: Postsplenectomy infections. South Med J 85:1220-1226, 1992
11. Holdsworth RJ, Irving AD, Cuschieri A: Postsplenectomy sepsis and its mortality rate: actual versus perceived risks. Br J Surg 78:1031-1038, 1991
12. Lane PA: The spleen and children. Curr Opin Pediatr 7:36-41, 1995
13. Waghorn DJ: Prevention of postslenectomy sepsis. Lancet 341:248, 1993
14. Hilleman MR, McLean AA, Vella PP, et al: Polyvalent pneumococcal polysaccharide vaccines. Bull WHO 56:371-375, 1978
15. Shatz DV, Schinsky MF, Pais LB, et al: Immune responses of splenectomized trauma patients to the 23-valent pneumococcal polysaccharide vaccine at 1 versus 7 versus 14 days after splenectomy. J Trauma 44:760-765, 1998
16. Kafidi KT, Rotschafer JC: Bacterial vaccines for splenectomized patients. Drug Intell Clin Pharmacol 22:192-197, 1988
17. Borgono JM, McLean AA, Veil PP: Vaccination and revaccination with polyvalent pneumococcal polysaccharide vaccines in adults and infants. Proc Soc Exp Biol Med 157:148-154, 1978
18. The Immunisation Practices Advisory Committee (Centers for Disease Control): Pneumococcal polysaccharide vaccine. MMWR 30:410-419, 1981
19. Department of Health: Immunisation against infections disease. London: HMSO, 102, 1992
20. Konradsen HB. Pedersen FK, Henrichsen J: Pneumococcal revaccination of splenectomized children. Pediatr Infect Dis J 9:258-263, 1990
21. Frank EL, Neu HC: Postsplenectomy infection. Surg Clin North Am 61:135-155, 1981
22. Ziemski JM, Rudowski WJ, Jaskowiak W, et al: Evaluation of early postsplenectomy complications. SG&O 165:507-513, 1987