Autogenous regulation of the Bacillus anthracis pag operon

Journal of Bacteriology

Volumn 181, Issue 15, 1999, Pages 4485-4492

  Hoffmaster, Alex R ^a   Koehler, Theresa M ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL TOXIN; CELL RECEPTOR; MESSENGER RNA;

ARTICLE; AUTOREGULATION; BACILLUS ANTHRACIS; BACTERIAL VIRULENCE; CELL MEMBRANE; EDEMA; GENE EXPRESSION REGULATION; GENE STRUCTURE; GENE TRANSLOCATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PRIORITY JOURNAL; RNA TRANSCRIPTION; TARGET CELL; TRANSCRIPTION TERMINATION;

BACILLUS ANTHRACIS; BACTERIA (MICROORGANISMS); POSIBACTERIA; PROKARYOTA;

EID: 0032783297     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.181.15.4485-4492.1999     Document Type: Article

References (36)

1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1996. Current protocols in molecular biology. John Wiley & Sons, New York, N.Y.
2. Bartkus, J. M., and S. H. Leppla. 1989. Transcriptional regulation of the protective antigen gene of Bacillus anthracis. Infect. Immun. 57:2295-2300.
3. Camilli, A., D. A. Portnoy, and P. Youngman. 1990. Insertional mutagenesis of Listeria monocytogenes with a novel Tn917 derivative that allows direct cloning of DNA flanking transposon insertions. J. Bacteriol. 172:3738-3744.
4. Cataldi, A., A. Fouet, and M. Mock. 1992. Regulation of pag gene expression in Bacillus anthracis: use of apag-lacZ transcriptional fusion. FEMS Microbiol. Lett. 98:89-94.
5. Cataldi, A., E. Labruyere, and M. Mock. 1990. Construction and characterization of a protective antigen-deficient Bacillus anthracis strain. Mol. Microbiol. 4:1111-1117.
6. 2/bicarbonate, affects AtxA synthesis. Infect. Immun. 65:2576-2582.
7. Dai, Z., J.-C. Sirard, M. Mock, and T. M. Koehler. 1995. The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence. Mol. Microbiol. 16:1171-1181,
8. Green, B. D., L. Battisti, T. M. Koehler, and C. B. Thorne. 1985. Demonstration of a capsule plasmid in Bacillus anthracis. Infect. Immun. 49:291-297.
9. Guignot, J., M. Mock, and A. Fouet. 1997. AtxA activates the transcription of genes harbored by both Bacillus anthracis virulence plasmids. FEMS Microbiol. Lett. 147:203-207.
10. 2-enhanced non-toxin gene expression in Bacillus anthracis. Infect. Immun. 65:3091-3099.
11. Koebler, T. M. Unpublished results.
12. 2 and a trans-acting element activate transcription from one of two promoters. J. Bacteriol. 176:586-595.
13. Kondorosi, E., M. Pierre, M. Cren, U. Haumann, M. Buire, B. Hoffmann, J. Schell, and A. Kondorosi. 1991. Identification of NolR, a negative transacting factor controlling the nod regulon in Rhizobium meliloti. J. Mol. Biol. 222:885-896.
14. Lebrun, M., A. Audurier, and P. Cossart. 1994. Plasmid-borne cadmium resistance genes in Listeria monocytogenes are similar to cadA and cadC of Staphylococcus aureus and are induced by cadmium. J. Bacteriol. 176:3040-3048.
15. Leppla, S. H. 1995. Anthrax toxins, p. 543-572. In J. Moss, B. Iglewski, M. Vaughan, and A. T. Tu (ed.), Bacterial toxins and virulence factors in disease. Marcel Dekker, New York, N.Y.
16. Leppla, S. H. 1988. Production and purification of anthrax toxin. Methods Enzymol. 165:103-116.
17. Mock, M., E. Labruyere, P. Glaser, A. Danchin, and A. Ullmann. 1988. Cloning and expression of the calmodulin-sensitive Bacillus anthracis adenylate cyclase in Escherichia coli. Gene 64:277-284.
18. Perez-Casal, J., M. G. Caparon, and J. R. Scott. 1991. Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systems. J. Bacteriol. 173:2617-2624.
19. Petosa, C., R. J. Collier, K. R. Klimpel, S. H. Leppla, and R. C. Liddington. 1997. Crystal structure of the anthrax toxin protective antigen. Nature 385: 833-838.
20. Pezard, C., P. Berche, and M. Mock. 1991. Contribution of individual toxin components to virulence of Bacillus anthracis. Infect. Immun. 59:3472-3477.
21. Ristroph, J. D., and B. E. Ivins. 1983. Elaboration of Bacillus anthracis antigens in a new, defined culture medium. Infect. Immun. 39:483-486.
22. Robertson, D., and S. H. Leppla. 1986. Molecular cloning and expression in Escherichia coli of the lethal factor gene of Bacillus anthracis. Gene 44:71-78.
23. Robertson, D. L., M. T. Tippetts, and S. H. Leppla. 1988. Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): a calmodulin-dependent adenylate cyclase. Gene 73:363-371.
24. Sirard, J.-C., M. Mock, and A. Fouet. 1995. Molecular tools for the study of transcriptional regulation in Bacillus anthracis. Res. Microbiol. 146:729-737.
25. Sirard, J.-C., M. Mock, and A. Fouet. 1994. The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature. J. Bacteriol. 176:5188-5192.
26. Thorne, C. B. 1985. Genetics of Bacillus anthracis, p. 56-62. In L. Leive (ed.). Microbiology. American Society for Microbiology, Washington, D.C.
27. Thorne, C. B., and F. C. Belton. 1957. An agar-diffusion method for titrating Bacillus anthracis immunizing antigen and its application to a study of antigen production. J. Gen. Microbiol. 17:505-516.
28. Tsui, H.-C. T., A. J. Pease, T. M. Koehler, and M. E. Winkler. 1994. Detection and quantitation of RNA transcribed from bacterial chromosomes and plasmids, p. 179-204. In K. W. Adolph (ed.), Molecular microbiology techniques, Part A. Academic Press Inc., San Diego, Calif.
29. Uchida, I., J. M. Hornung, C. B. Thorne, K. R. Klimpel, and S. H. Leppla. 1993. Cloning and characterization of a gene whose product is a trans-activator of anthracis toxin synthesis. J. Bacteriol. 175:5329-5338.
30. Uchida, I., S.-I. Makino, T. Sekizaki, and N. Terakado. 1997. Cross-talk to the genes for Bacillus anthracis capsule synthesis by atxA, the gene encoding the trans-activator of anthrax toxin synthesis. Mol. Microbiol. 23:1229-1240.
31. Vietri, N. J., R. Marrero, T. A. Hoover, and S. L. Welkos. 1995. Identification and characterization of a trans-activator involved in the regulation of encapsulation by Bacillus anthracis. Gene 152:1-9.
32. Vodkin, M. H., and S. H. Leppla. 1983. Cloning of the protective antigen gene of Bacillus anthracis. Cell 34:693-697.
33. Welkos, S. L., J. R. Lowe, F. Eden-McCutchan, M. Vodkin, S. H. Leppla, and J. J. Schmidt. 1988. Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis. Gene 69:287-300.
34. Wesche, J., J. L. Elliott, P. O. Falnes, S. Olsnes, and R. J. Collier. 1998. Characterization of membrane translocation by anthrax protective antigen. Biochemistry 37:15737-15746.
35. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33:103-119.
36. Yansura, D. F., and D. J. Henner. 1984. Use of the Escherichia coli lac repressor and operator to control gene expression in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 81:439-443.