Wet decontamination-induced stratum corneum hydration - Effects on the skin barrier function to diethylmalonate

Journal of Applied Toxicology

Volumn 19, Issue 4, 1999, Pages 285-290

  Loke, Weng Keong ^a   U, Soo Hway ^a   Lau, Sok Kiang ^a   Lim, Jui Sui ^a   Tay, Guan Sze ^a   Koh, Cheng Heng ^a  

^a NONE

Author keywords

Barrier function; Diethylmalonate; Enhanced penetration; Nerve agent; Salinity; Stratum corneum; Surfactants; Transient hydration; Wet decontamination

Indexed keywords

ANIONIC SURFACTANT; CATIONIC SURFACTANT; MALONIC ACID; MALONIC ACID DIETHYL ESTER; NONIONIC SURFACTANT; SURFACTANT; UNCLASSIFIED DRUG; WATER;

ADULT; AGED; AQUEOUS SOLUTION; ARTICLE; HUMAN; HUMAN TISSUE; HYDRATION; IONIZATION; PRIORITY JOURNAL; SALINITY; SKIN DECONTAMINATION; STRATUM CORNEUM;

AGED; AGED, 80 AND OVER; BENZETHONIUM; BODY WATER; CADAVER; DECONTAMINATION; HUMANS; MALE; MALONATES; MIDDLE AGED; SKIN; SKIN ABSORPTION; SODIUM DODECYL SULFATE;

EID: 0032782560     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1263(199907/08)19:4<285::AID-JAT580>3.0.CO;2-X     Document Type: Article

References (15)

1. R. C. Wester and H. I. Maibach, In vivo percutaneous absorption and decontamination of pesticides in humans. J. Toxicol. Environ. Health 16, 25-37 (1985).
2. R. P. Moody and B. Nadeau, An automated in vitro dermal absorption procedure: III. In vitro and in vivo comparison with the insect repellent N,N-diethyl-m-toluamide in mouse, rat, guinea pig, pig, human and tissue-cultured skin. Toxicol. in Vitro 7(2), 167-176 (1993).
3. R. Trapp, The detoxification and natural degradation of chemical warfare agents. In SIPRI Chemical And Biological Warfare Studies, 3rd Edn, ed. by R. Trapp, pp. 74-81. Taylor & Francis, Philadelphia, USA (1985).
4. D. E. Wurster, J. A. Ostrenga and I. A. Matheson, Jr., Sarin transport across excised human skin. I: Permeability and adsorption characteristics. J. Pharm. Sci. 68(11), 1406-1409 (1979).
5. W. G. Reifenrath, M. M. Mershon, F. B. Brinkley, G. A. Muira, C. A. Broomfield and H. B. Cranford, Evaluation of diethylmalonate as a simulant for 1,2,2-trimethylpropyl methylphosphonofluoridate (soman) in shower decontamination of the skin. J. Pharm. Sci. 73(10), 1388-1392 (1984).
6. P. Grandjean, Percutaneous absorption - sources of variation. In Skin Penetration: Hazardous Chemicals at Work, Publication No. EUR 12599 EN of the Commission of the European Communities, Scientific and Technical Communication Unit, 1st Edn, ed. by P. Grandjean, pp. 18-20, Taylor & Francis Inc, London, UK (1990).
7. R. C. Wester and H. I. Maibach, Percutaneous absorption of chemicals from water during swimming and bathing. In Health Risk Assessment, ed. by Wang, pp. 135-143. CRC Press, Florida, USA (1993).
8. C. V. Hooidonk, B. I. Ceulen, J. Bock and J. V. Genderen, CW agents and the skin: penetration and decontamination. In Proceedings on International Symposium for Protection Against Chemical Warfare Agents, pp. 153-160 Stockholm, Sweden (1983).
9. B. Idson, Percutaneous absorption. J. Pharm. Sci. 64(6), 901-924 (1975).
10. J. L. Zatz, Assessment of vehicle factors influencing percutaneous absorption. In In vitro Percutaneous Absorption: Principles, Fundamentals, and Applications, ed. by R. L Bronaugh and H. I. Maibach, p. 54. CRC Press, Florida, USA (1991).
11. E. Cronin and R. B. Stoughton, Percutaneous adsorption: regional variations and the effect of hydration and epidermal stripping. Br. J. Dermatol. 74, 265-272 (1962).
12. 14 acetylsalicyclic acid in excised human skin. J. Invest. Dermatol. 41, 307-311 (1963).
13. K. P. Wilhelm, A. B. Cua, H. H. Wolff and H. I. Maibach, Surfactant-induced stratum corneum hydration in vivo: prediction of the irrigation potential of anionic surfactants. J. Invest. Dermatol. 101(3), 310-315 (1993).
14. W. Matthies, Dermatological observations (humans). In Anionic Surfactants: Biochemistry, Toxicology, Dermatology, Vol. 43, ed. by C. Gloxhuber and K. Kunstler, pp. 291-321. Marcel Dekker, New York (1990).
15. H. P. Drobeck, Current topics on the toxicity of cationic surfactants. In Cationic Surfactants, Vol. 4, ed. by E. Jungermann, pp. 61-91. Marcel Dekker, New York (1990).