FR145715, a novel histamine H2 receptor antagonist, with specific anti-Helicobacter pylori activities

European Journal of Pharmacology

Volumn 378, Issue 3, 1999, Pages 299-310

  Ishikawa, Hirohumi ^a   Ito, Harunobu ^a   Higaki, Masahide ^a   Higaki, Mika ^a   Matsumoto, Yoshimi ^a   Kamimura, Toshiaki ^a   Katsura, Yousuke ^a   Tomishi, Tetsuo ^a   Inoue, Yoshikazu ^a   Takasugi, Hisashi ^a   Tomoi, Masaaki ^b   Krakowka, Steven ^c   Yoshida, Keizo ^d  

^a Med Chemistry Research Laboratories   (Japan)

^b Project Accelerating Staff   (Japan)

^c OHIO STATE UNIVERSITY   (United States)

^d Drug Discovery Laboratories P   (Japan)

Author keywords

FR145715; Helicobacter pylori; Histamine H2 receptor antagonist; Ulcer

Indexed keywords

FR 145715; HISTAMINE H2 RECEPTOR; HISTAMINE H2 RECEPTOR ANTAGONIST; RANITIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; GASTRITIS; HEART ATRIUM; HELICOBACTER PYLORI; IN VITRO STUDY; IN VIVO STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH ACID SECRETION; STOMACH POUCH; STOMACH ULCER; SWINE;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; ATRIAL FUNCTION; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRIC ACID; GASTRITIS; GUANIDINES; GUINEA PIGS; HEART ATRIA; HEART RATE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HISTAMINE; HISTAMINE H2 ANTAGONISTS; HYDROCHLORIC ACID; HYDROGEN-ION CONCENTRATION; IMMERSION; MALE; MICROBIAL SENSITIVITY TESTS; RATS; RATS, SPRAGUE-DAWLEY; RESTRAINT, PHYSICAL; STOMACH; STRESS; SWINE; THIAZOLES; WATER;

EID: 0032782078     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00466-5     Document Type: Article

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