The cytoadherence linked asexual gene family of Plasmodium falciparum: re there roles other than cytoadherence?

International Journal for Parasitology

Volumn 29, Issue 6, 1999, Pages 939-944

  Holt, Deborah C ^a   Gardiner, Donald L ^a   Thomas, Elizabeth A ^a   Mayo, Mark ^a   Bourke, Peter F ^a   Sutherland, Colin J ^a   Carter, Rod ^a   Myers, Garry ^a   Kemp, David J ^a   Trenholme, Katharine R ^a  

^a MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

Author keywords

CD36; Clag; Cytoadherence; Gene family; PfEMPI; Plasmodium falciparum

Indexed keywords

CD36 ANTIGEN; COMPLEMENTARY RNA; RECEPTOR;

CELL ADHESION; CHROMOSOME 9; CONFERENCE PAPER; ERYTHROCYTE; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIGENS, CD36; CELL ADHESION; ERYTHROCYTES; GENES, PROTOZOAN; HUMANS; MALARIA, FALCIPARUM; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS;

PLASMODIUM FALCIPARUM;

EID: 0032781659     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(99)00046-6     Document Type: Conference Paper

References (25)

1. Kilejian A. Characterization of a protein correlated with the production of knob-like protrusions on membranes of erythrocytes infected with Plasmodium falciparum. Proc Natl Acad Sci USA. 76:1979;4650-4653.
2. Crabb B.S., Cooke B.M., Reeder J.C.et al. Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress. Cell. 89:1997;287-296.
3. Baruch D.I., Pasloske B.L., Singh H.B.et al. Cloning the P. falciparum gene encoding PfEMP-1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes. Cell. 82:1995;77-87.
4. Smith J.D., Chitnis C.E., Craig A.G.et al. Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes. Cell. 82:1995;101-110.
5. Su X., Heatwole V.M., Wertheimer S.P.et al. The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of Plasmodium falciparum-infected erythrocytes. Cell. 82:1995;89-100.
6. Gardner J.P., Pinches R.A., Roberts D.J., Newbold C.I. Variant antigens and endothelial receptor adhesion in Plasmodium falciparum. Proc Natl Acad Sci USA. 93:1996;3503-3508.
7. Weber J.L. Interspersed repetitive DNA from Plasmodium falciparum. Mol Biochem Parasitol. 29:1988;117-124.
8. Limpaiboon T., Shirley M.W., Kemp D.J., Saul A. 7H8/6, A multicopy DNA probe for distinguishing isolates of Plasmodium falciparum. Mol Biochem Parasitol. 47:1991;197-206.
9. Cheng Q., Lawrence G., Reed C.et al. Measurement of Plasmodium falciparum growth rates in vivo: a test of malaria vaccines. Am J Trop Med Hyg. 57:1997;495-500.
10. Corcoran L.M., Thompson J.K., Walliker D., Kemp D.J. Homologous recombination within subtelomeric repeat sequences generates chromosome size polymorphisms in P. falciparum. Cell. 53:1988;807-813.
11. Crandall I., Collins W.E., Gysin J., Sherman I.W.et al. Synthetic peptides based on motifs present in human band 3 protein inhibit cytoadherence/sequestration of the malaria parasite Plasmodium falciparum. Proc Natl Acad Sci USA. 90:1993;4703-4707.
12. Ockenhouse C.F., Klotz F.W., Tandon N.N., Jamieson G.A. Sequestrin, a CD36 recognition protein on Plasmodium falciparum malaria-infected erythrocytes identified by anti-idiotype antibodies. Proc Natl Acad Sci USA. 88:1991;3175-3179.
13. Berendt A., Craig A. Plasmodium falciparum malaria-sticky jams and PECAM pie. Nat Med. 3:1997;1315-1316.
14. Udeinya I.J., Graves P.M., Carter R., Aikawa M., Miller L.H. Plasmodium falciparum: effect of time in continuous culture on binding to human endothelial cells and amelanotic melanoma cells. Exp Parasitol. 56:1983;207-214.
15. Shirley M.W., Biggs B.A., Forsyth K.P.et al. Chromosome 9 from independent clones and isolates of Plasmodium falciparum undergoes subtelomeric deletions with similar breakpoints in vitro. Mol Biochem Parasitol. 40:1990;137-146.
16. Day K., Karamalis F., Thompson J.et al. Genes necessary for expression of a virulence determinant and for transmission of Plasmodium falciparum are located on a 0.3-megabase region of chromosome 9. Proc Natl Acad Sci USA. 90:1993;8292-8296.
17. Barnes D.A., Thompson J., Triglia T., Day K., Kemp D.J. Mapping the genetic locus implicated in cytoadherence of Plasmodium falciparum to melanoma cells. Mol Biochem Parasitol. 66:1994;21-29.
18. Chaiyaroj S.C., Coppel R.C., Magowan C., Brown G.V. A Plasmodium falciparum isolate with a chromosome 9 deletion expresses a trypsin-resistant cytoadherence molecule. Mol Biochem Parasitol. 67:1994;21-30.
19. Bourke P.F., Holt D.C., Sutherland C.J., Kemp D.J. Disruption of a novel open reading frame of Plasmodium falciparum chromosome 9 by subtelomeric and internal deletions can lead to loss or maintenance of cytoadherence. Mol Biochem Parasitol. 82:1996;25-36.
20. Graves P.M., Carter R., Keystone J.S., Seeley D.C. Drug sensitivity and isoenzyme type in cloned lines of Plasmodium falciparum. Am J Trop Med Hyg. 33:1984;212-219.
21. Holt DC, Bourke PF, Mayo M, Kemp DJ. A high resolution map of Plasmodium falciparum chromosome 9. Mol Biochem Parasitol 1999; in press.
22. Barnes W.M. PCR amplification of up to 35-kb DNA with high fidelity and high yield from λ bacteriophage templates. Proc Natl Acad Sci USA. 91:1994;2216-2220.
23. Gardner M.J., Tettelin H., Carucci D.J.et al. Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Science. 282:1998;1126-1132.
24. Crabb B., Cowman A. Characterisation of promotors and stable transfection by homologous and nonhomologous recombination in Plasmodiun falciparum. Proc Natl Acad Sci USA. 93:1996;7289-7294.
25. Wu Y., Kirkman L.A., Wellems T.E. Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Proc Natl Acad Sci USA. 93:1996;1130-1143.