L-Deprenyl inhibits tumor growth, reduces serum prolactin, and suppresses brain monoamine metabolism in rats with carcinogen-induced mammary tumors

Endocrine

Volumn 10, Issue 3, 1999, Pages 225-232

  ThyagaRajan, Srinivasan ^a,b   Quadri, S Kaleem ^a  

^a KANSAS STATE UNIVERSITY   (United States)

^b LOMA LINDA UNIVERSITY   (United States)

Author keywords

Breast cancer; Catecholamines; Indoleamines; Medial basal hypothalamus; Prolactin

Indexed keywords

BRAIN MONOAMINE; CATECHOLAMINE; DIHYDROXYPHENYLACETIC ACID; DIMETHYLBENZ[A]ANTHRACENE; DOPAMINE; HOMOVANILLIC ACID; INDOLEAMINE; MONOAMINE OXIDASE B INHIBITOR; NORADRENALIN; PROLACTIN; SELEGILINE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; BREAST TUMOR; CANCER INHIBITION; CARCINOGENESIS; CATECHOLAMINE BLOOD LEVEL; CATECHOLAMINE METABOLISM; CONTROLLED STUDY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOTHALAMUS; MONOAMINE METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; RADIOIMMUNOASSAY; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR VOLUME;

EID: 0032781645     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/bf02738621     Document Type: Article

References (34)

1. Birkmayer, W., Knoll, J., Riederer, P., and Youdim, M. B. H. (1983). Mod. Probl. Pharmacopsychiatry 19, 170-176.
2. Tariot, P. N., Sunderland, T., Weingartner, H., Murphy, D. L., Welkowitz, J. A., Thompson, K., and Cohen, R. M. (1987). Psychopharmacology 91, 489-495.
3. Knoll, J., Dallo, J., and Yen, T. T. (1989). Life Sci. 45, 525-532.
4. Milgram, N. W., Racine, R. J., Nellis, P., Mendonca, A., and Ivy, G. O. (1990) Life Sci. 47, 415-420.
5. Brandeis, R., Sapir, M., Kapon, Y., Borelli, G., Cadel, S., and Valsecchi, B. (1991). Pharmacol. Biochem. Behav. 39, 297-304.
6. Knoll, J. (1988). Mech. Ageing Dev. 46, 237-262.
7. Meites, J. (1982). Neuroendocrinology 34, 151-156.
8. MohanKumar, P. S., ThyagaRajan, S., and Quadri, S. K. (1994). Endocrinology 135, 119-126.
9. ThyagaRajan, S., MohanKumar, P. S., and Quadri, S. K. (1995), Brain Res. 689, 122-128.
10. MohanKumar, P. S., ThyagaRajan, S., and Quadri, S. K. (1995). Brain Res. Bull. 38, 561-564.
11. MohanKumar, P. S., ThyagaRajan, S., and Quadri, S. K. (1997) Brain Res. Bull. 42, 265-271.
12. Meites, J. (1980) J. Neural Transm. 48, 25-42.
13. Quadri, S. K., Kledzik, G. S., and Meites, J. (1973). Proc. Soc. Exp. Biol. Med. 142, 759-761.
14. Quadri, S. K., Clark, J. L., and Meites, J. (1973). Proc. Soc. Exp. Biol. Med. 142, 22-26.
15. Leung, F. C., Aylsworth, C. F., and Meites, J. (1983). Proc. Soc. Exp. Biol. Med. 173, 159-163.
16. ThyagaRajan, S., Meites, J., and Quadri, S. K. (1993) Proc. Soc. Exp. Biol. Med. 203, 236-242.
17. ThyagaRajan, S., Meites, J., and Quadri, S. K. (1995) Endocrinology 136, 1103-1110.
18. MohanKumar, P. S., Meites, J., and Quadri, S. K. (1994) Life Sci. 54, 841-845.
19. Welsch, C. W. and Nagasawa, H. (1977). Cancer Res., 37, 951-963.
20. ThyagaRajan, S., Felten, S. Y., and Felten, D. L. (1998). Cancer Lett. 123, 177-183.
21. Demarest, K. T. and Moore, K. E. (1979). J. Neural Transm. 46, 263-277.
22. Gudelsky, G. A. and Metzer, H. Y. (1984). Neuroendocrinology 38, 51-55.
23. MohanKumar, P. S. and Quadri, S. K. (1992). 9th International Congress of Endocrinology, Nice, France, 555 (Abstract).
24. ThyagaRajan, S. and Quadri, S. K. (1992). 74th Annual Meeting of the Endocrine Society, San Antonio, TX, 431 (Abstract).
25. Dickson, R. B. and Lippman, M. E. (1992) Semin. Oncol. 19, 286-298.
26. Szepeshazi, K., Milovanovic, S., Lapis, K., Groot, K., and Schally, A. V. (1992). Breast Cancer Res. Treat. 21, 181-192.
27. Bartke, A., Cecim, M., Tang, K., Steger, R. W., Chandrashekar, V., and Turyn, D. (1994). Proc. Soc. Exp. Biol. Med. 206, 345-359.
28. ThyagaRajan, S., Madden, K. S., Kalvass, J. C., Dimitrova, S., Felten, S. Y., and Felten, D. L. (1998). J. Neuroimmunol. 92, 9-21.
29. Yang, H-Y. T. and Neff, H. (1974). J. Pharmacol. Exp. Ther. 189, 733-740.
30. Green, A. R., Mitchell, B. D., Tordoff, A. F. C., and Youdim, M. B. H. (1977). Br. J. Pharmacol. 60, 343-349.
31. Ekstedt, B., Magyar, K., and Knoll, J. (1979). Biochem. Pharmacol. 28, 919-923.
32. Waldmeier, P. C. and Felner, A. E. (1979). Biochem. Pharmacol. 27, 801-802.
33. Heinonen, E. H., Antilla, M. I., and Lammintausta, R. A. S. (1994). Clin. Pharmacol. Ther. 56, 742-749.
34. Nickel, B., Szelenyi, I., and Schulze, G. (1994). Clin. Pharmacol. Ther. 56, 757-767.