A familial case of recurrent hydatidiform molar pregnancies with biparental genomic contribution

Human Genetics

Volumn 105, Issue 1-2, 1999, Pages 112-115

  Helwani, Mazen N ^a   Seoud, Muhieddine ^a   Zahed, Laila ^a   Zaatari, Ghazi ^a   Khalil, Ali ^a   Slim, Rima ^a  

^a AMERICAN UNIVERSITY OF BEIRUT   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; CASE REPORT; DEVELOPMENTAL DISORDER; EMBRYO DEVELOPMENT; FAMILIAL DISEASE; FEMALE; GENOTYPE; HUMAN; HYDATIDIFORM MOLE; KARYOTYPE; PLACENTA VILLUS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TROPHOBLASTIC TUMOR;

EID: 0032780885     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004399900088     Document Type: Article

References (21)

1. Ambani LM, Vaidya RA, Rao CS, Daftary SD, Motashaw ND (1980) Familial occurrence of trophoblastic disease - report of recurrent molar pregnancies in sisters in three families. Clin Genet 18 : 27-29
2. Berkowitz RS, Im SS, Bernstein MR. Goldstein DP (1998) Gestational trophoblastic disease, subsequent pregnancy outcome, including repeat molar pregnancy. J Reprod Med 43 : 81-86
3. Bonilla-Musoles F (1993) The diagnosis of gestational trophoblastic neoplasm by ultrasonography. In: Chervenak FA, Isaacson GC, Campbell S (eds) Ultrasound in obstretrics and gynecology. Little Brown, Boston, pp 1665-1673
4. Copeland LJ (1993) Gestational trophoblastic neoplasia. In: Copeland LJ (ed) Textbook of gynecology. Saunders, Philadelphia, pp 1133-1151
5. Dib C, Faure S, Fizames C, Samson D, Drouot N, Vignal A, Millasseau P, Marc S, Hazan J, Seboun E, Lathrop M, Gyapay G, Morissette J, Weissenbach J (1996) A comprehensive genetic map of the human genome based on 5264 microsatellites. Nature 380 : 152-154
6. Fisher RA, Newlands ES (1998) Gestational trophoblastic disease: molecular and genetic studies. J Reprod Med 43 : 87-97
7. Kajii T, Ohama K (1977) Androgenetic origin of hydatidiform mole. Nature 268 : 633-634
8. Kircheisen R, Ried T (1991) Hydatidiform moles. Hum Reprod 9 : 1783-1785
9. Kovacs B, Shahbharami B, Tast D, Curtin JP (1991) Molecular genetic analysis of complete hydatidiform moles. Cancer Genet Cytogenet 54 : 143-152
10. La Vecchia C, Franceschi S, Fasoli M, Mangioni C (1982) Gestational trophoblastic neoplasms in homozygous twins. Obstet Gynecol 60 : 250-252
11. Lindor NM, Ney JA, Gaffey TA, Jenkins RB, Thibodeau SN, Dewald GW (1992) A genetic review of complete and partial hydatidiform moles and nonmolar triploidy. Mayo Clin Proc 67 : 791-799
12. Mangili G, Parazzini F. Maggi R, Spolti N (1993) Repeated gestational trophoblastic disease after natural and heterologous assisted conception. J Reprod Med 38 : 405-406
13. Parazzini F, La Vecchia C, Franceschi S, Mangili G (1984) Familial trophoblastic disease: case report. Am J Obstet Gynecol 149 : 382-383
14. Parazzini F, La Vecchia C, Pampallona S, Stat BSD, Franceschi S (1985) Reproductive patterns and the risk of gestational trophoblastic disease. Am J Obstet Gynecol 152 : 866-870
15. Saouda M, Mansour A, Bou M, El Zir E, Mustapha M, Chaib H, Nehme A, Megarbane A, Loiselet J, Petit C, Slim R (1998) The Usher syndrome in the Lebanese population and further refinement of the USH2 A candidate region. Hum Genet 103 : 193-198
16. Schultz AG, Heyner S (1992) Gene expression in pre-implantation mammalian embryos. Mutat Res 296 : 17-31
17. Seoud M, Khalil A, Frangieh A, Zahed L, Azar G, Nuwayri-Salti N (1995) Reccurent molar pregnancies in a family with extensive intermarriage: report of a family and review of the literature. Obstet Gynecol 86 : 692-695
18. Sunde L, Vejerslev LO, Jensen MP, Pedersen S, Hertz JM, Bolund L (1993) Genetic analysis of repeated, biparental, diploid, hydatidiform moles. Cancer Genet Cytogenet 66 : 16-22
19. Vejerslev L, Sunde L, Hansen BF, Larsen JK, Christensen IJ, Larsen G (1991) Hydatidiform mole and fetus with normal karyotype: support of a separate entity. Obstet Gynecol 77 : 868-874
20. Wilkins-Haug L (1993) The emerging genetic theories of unstable DNA, uniparental disomy, and imprinting. Curr Opin Obstet Gynecol 5 : 179-185
21. Zaragova MV, Keep D, Genest DR, Hassold T, Redline RW (1997) Early complete hydatidiform moles contain inner cell mass derivatives. Am J Med Genet 70 : 273-277