The relative potency between high dose oral oxycodone and intravenous morphine: A case illustration

Journal of Pain and Symptom Management

Volumn 18, Issue 1, 1999, Pages 53-55

  Zhukovsky, Donna S ^a   Walsh, Declan ^a   Doona, Marie ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Morphine; Opioid administration and dose; Opioid equianalgesic ratios; Opioid dose response relationship; Oxycodone

Indexed keywords

MORPHINE; MORPHINE SULFATE; OXYCODONE; PARACETAMOL; PERCOCET;

ADULT; ARTICLE; CANCER PAIN; CASE REPORT; DOSE RESPONSE; DRUG MEGADOSE; DRUG POTENCY; DRUG SAFETY; DRUG TOLERANCE; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; UTERINE CERVIX CARCINOMA;

ADMINISTRATION, ORAL; ADULT; ANALGESICS, OPIOID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MORPHINE; OXYCODONE; TREATMENT OUTCOME;

EID: 0032780374     PISSN: 08853924     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0885-3924(99)00024-X     Document Type: Article

References (13)

1. Roxane Laboratories, Inc. Personal communication.
2. Glare P.A., Walsh D. Oxycodone. a substitute for morphine in cancer pain management [letter] Palliative Medicine. 6:1992;79-80.
3. Glare P.A., Walsh T.D. Dose-ranging study of oxycodone for chronic pain in advanced cancer. J Clin Oncol. 11:1993;973-978.
4. Kalso E., Vainio A. Morphine and oxycodone hydrochloride in the management of cancer pain. Clin Pharmacol Ther. 47:1990;639-646.
5. Kaplan R, Parris WCV, Citron ML, Zhukovsky D, Khojasteh A, Buckley BJ, Reder RF and Kaiko RF. Comparison of controlled release and immediate-release oxycodone tablets in patients with cancer pain: A double blind study. [abstract]. International Association for the Study of Pain: Eighth World Congress on Pain, Vancouver, B.C., Canada, August 17-22, 1996.
6. Poyhia R., Vainio A., Kalso E. A review of oxycodone's clinical pharmacokinetics and pharmacodynamics. J Pain Symptom Manage. 8:1993;63-67.
7. Kaiko R.F. The use of controlled release opioids. Parris W.C.V. Cancer pain management. principles and practice:1997;69-90 Butterworth-Heinemann, Boston.
8. Management of Cancer Pain. Clinical Practice Guideline Number 9, U.S. Department of Health and Human Services, Agency for Health Care Policy and Research Publication No. 94-0592, 1994.
9. Beaver W.T., Wallenstein S.L., Rogers A.et al. Analgesic studies of codeine and oxycodone in patients with cancer. I. Comparisons of oral with intramuscular codeine and of oral with intramuscular oxycodone. J Pharmacol Exper Ther. 207:1978;92-100.
10. Beaver W.T., Wallenstein S.L., Rogers A.et al. Analgesic studies of codeine and oxycodone in patients with cancer. II. Comparisons of oral with intramuscular codeine and of oral with intramuscular oxycodone. J Pharmacol Exper Ther. 207:1978;101-108.
11. Houde R.W. Systemic analgesics and related drugs. Narcotic analgesics Bonica J.J., Ventafridda V. Advances in Pain Research and Therapy, Vol 2. 1979;263-273 Raven Press, New York.
12. Kaiko R., Lacouture P., Hopf K.et al. Analgesic onset and potency of oral controlled-release (CR) oxycodone and CR morphine. [abstract]. Clin Pharmacol Ther. 59:1996;130.
13. Inturrisi C.E., Hanks G. Opioid analgesic therapy. Doyle D., Hanks G.W., McDonald N. Oxford Textbook of Palliative Medicine. 1993;166-182 Oxford University Press, Oxford.