Increased levels of serum interleukin-12 in Graves' disease

European Journal of Endocrinology

Volumn 141, Issue 2, 1999, Pages 111-116

  Tamaru, Masaaki ^a   Matsuura, Bunzo ^a   Onji, Morikazu ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; LIOTHYRONINE; PROPYLTHIOURACIL; THIAMAZOLE; THYROGLOBULIN; THYROXINE;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GRAVES DISEASE; HASHIMOTO DISEASE; HUMAN; HYPERTHYROIDISM; MALE; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; FEMALE; GRAVES DISEASE; HUMANS; INTERLEUKIN-12; MALE; MIDDLE AGED; THYROID HORMONES; THYROIDITIS, AUTOIMMUNE;

EID: 0032780137     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1410111     Document Type: Article

References (37)

1. Del Prete GF, Vercelli D, Tiri A, Maggi E, Mariotti S, Pinchera A, Ricci M & Romagnani S. In vivo activated cytotoxic T cells in the thyroid infiltrate of patients with Hashimoto's thyroiditis. Clinical and Experimental Immunology 1986 65 140-147.
2. Del Prete GF, Tiri A, de Carli M, Mariotti S, Pinchera A, Chretien I, Romagnani S & Ricci M. High potential to tumor necrosis factor alpha (TNF-α) production of thyroid infiltrating T lymphocytes in Hashimoto's thyroiditis: a peculiar feature of destructive thyroid autoimmunity. Autoimmunity 1989 4 267-276.
3. Watson PF, Pickerill AP, Davies R & Weetman AP. Semi-quantitative analysis of interleukin-1, interleukin-6 and interleukin-8 mRNA expression by human thyrocytes. Journal of Molecular Endocrinology 1995 15 11-21.
4. Grubeck-Loebenstein B, Buchan G, Chantry D, Kassal H, Londei M, Pirich K, Barrett K, Turner M, Waldhaual W & Feldmann M. Analysis of intrathyroidal cytokine production in thyroid autoimmune disease: thyroid follicular cells produce interleukin-1 and interleukin-6. Clinical and Experimental Immunology 1989 77 324-330.
5. Zheng RQ, Abney ER, Chu CQ, Field M, Maini RN, Lamb JR & Feldmann M. Detection of in vivo production of tumor necrosis factor-alpha by human thyroid epithelial cells. Immunology 1992 75 456-462.
6. Todd I, Pujol-Borrell R, Hammond LJ, Bottazzo GF & Feldmann M. Interferon-γ induces HLA-DR expression by thyroid epithelium. Clinical and Experimental Immunology 1985 11 265-273.
7. Weetman AP & Borysiewicz LK. Regulation of major histocompatibility complex class II antigen expression by the FRTL-5 rat thyroid cell line. Journal of Endocrinology 1987 115 481-487.
8. Weetman AP & Rees AJ. Synergistic effects of recombinant tumor necrosis factor-α (TNF-α) and γ-interferon (γ-IFN) on rat thyroidal cell growth and Ia antigen expression. Immunology 1988 63 285-289.
9. Weetman AP, Cohen SB, Makgoba MW & Borysiewicz LK. Expression of an intercellular adhesion molecule, ICAM-1, by human thyroid cells. Journal of Endocrinology 1989 122 185-191.
10. Tandon N, Makgoba MW, Gahmberg CG & Weetman AP. The expression and role in T cell adhesion of LFA-3 and ICAM-2 on human thyroid cells. Clinical Immunology and Immunopathology 1992 64 30-35.
11. Vargas F, Tolosa E, Sospedra M, Catalfamo M, Lucas-Martin A, Obiols G & Pujol-Borrell R. Characterization of neural cell adhesion molecule (NCAM) expression in thyroid follicular cells: induction by cytokines and over-expression in autoimmune glands. Clinical and Experimental Immunology 1994 98 478-488.
12. Kobayashi M, Fitz L, Ryan M, Hewick RM, Clark SC, Chan S, Loudon R, Sherman F, Perussia B & Trinchieri G. Identification and purification of natural killer cell stimulatory factor (NKSF): a cytokine with multiple biologic effects on human lymphocytes. Journal of Experimental Medicine 1989 170 827-845.
13. Stern AS, Podlaski FJ, Hulmes JD, Pan YC, Quinn PM, Wolitzky AG, Familletti PC, Stremlo DL, Truitt T, Chizzonite R et al. Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells. Proceedings of the National Academy of Sciences of the USA 1990 87 6808-6812.
14. Manetti R, Parronchi P, Giudizi MG, Piccinni MP, Maggi E, Trinchieri G & Romagnani S. Natural killer cell stimulatory factor (interleukin 12 (IL-12)) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. Journal of Experimental Medicine 1993 177 1199-1204.
15. Ling P, Gately MK, Gubler U, Stern AS. Lin P, Hollfelder K, Su C, Pan YC & Hakimi J. Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. Journal of Immunology 1995 154 116-127.
16. Zhang M, Gately MK, Wang E, Wolf SF, Lu S, Modlin RL & Barnes PF. Interleukin 12 at the site of disease in tuberculosis. Journal of Clinical Investigation 1994 93 1733-1739.
17. D'Andrea A, Rengaraju M, Valiante NM, Chehimi J, Kubin M, Aste M, Chan SH, Kobayashi M, Young D, Nickbarg E et al. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. Journal of Experimental Medicine 1992 176 1587-1398.
18. Ajjan RA, Watson PF & Weetman AP. Detection of IL-12, IL-13. and IL-15 messenger ribonucleic acid in the thyroid of patients with autoimmune thyroid disease. Journal of Clinical Endocrinology and Metabolism 1997 82 666-669.
19. Zipris D, Greiner DL, Malkani S, Whalen B, Mordes JP & Rossini AA. Cytokine gene expression in islets and thyroids of BB rats: IFN-γ and IL-12 p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats. Journal of Immunology 1996 156 1315-1321.
20. Braley-Mullen H, Sharp GC, Tang H, Chen K, Kyriakos M & Bickel JT. Interleukin-12 promotes activation of effector cells that induce a severe destructive granulomatous form of murine experimental autoimmune thyroiditis. American Journal of Pathology 1998 152 1347-1358.
21. Trinchieri G. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity. Annual Review of Immunology 1995 13 251-276.
22. Halpern MD, Kurlander RJ & Pisetsky DS. Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha. Cellular Immunology 1996 167 72-78.
23. Heinzel FP, Rerko RM, Ling P, Hakimi J & Schoehaut DS. Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of gamma interferon. Infection and Immunology 1994 62 4244-4249.
24. Wysocka M, Kubin M, Vieira LQ, Ozmen L, Garotta G, Scott P & Trinchieri G. Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice. European Journal of Immunology 1995 25 672-676.
25. Yanagida T, Kato T, Igarashi O, Inoue T & Nariuchi H. Second signal activity of IL-12 on the proliferation and IL-2 R expression of T helper cell-1 clone. Journal of Immunology 1994 152 4919-4928.
26. Nakanishi K, Taniguchi Y & Ohta Y. Increased soluble interleukin 2 receptor levels in autoimmune thyroid disease. Acta Endocrinologica 1991 125 253-258.
27. Trembleau S, Germann T, Gately MK & Adorini L. The role of IL-12 in the induction of organ-specific autoimmune diseases. Immunology Today 1995 16 383-386.
28. Leonard JP, Waldburger KE & Goldman SJ. Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12. Journal of Experimental Medicine 1995 181 381-386.
29. Germann T, Szeliga J, Hess H, Storkel S, Podlaski FJ, Gately MK, Schmitt E & Rude E. Administration of interleukin 12 in combination with type II collagen induces severe arthritis in DBA/1 mice. Proceedings of the National Academy of Sciences of the USA 1995 92 4823-4827.
30. Neurath MF, Fuss I, Kelsall BL, Stuber E & Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. Journal of Experimental Medicine 1995 182 1281-1290.
31. Williamson E, Garside P, Baradley JA & Mowat AM. IL-12 is a central mediator of acute graft-versus-host disease in mice. Journal of Immunology 1996 157 689-699.
32. Seder RA, Kelsall BL & Jankovic D. Differential roles for IL-12 in the maintenance of immune responses in infectious versus autoimmune disease. Journal of Immunology 1996 157 2745-2748.
33. Rabinovitch A. Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM: therapeutic intervention by immunostimulation. Diabetes 1994 43 613-621.
34. Liblau RS, Singer SM & McDevitt HO. Th1 and Th2 CD4+T cells in the pathogenesis of organ-specific autoimmune diseases. Immunology Today 1995 16 34-38.
35. Paul WE & Seder RA. Lymphocyte responses and cytokines. Cell 1994 76 241-251.
36. Biron CA & Gazzinelli RT. Effects of IL-12 on immune responses to microbial infections: a key mediator in regulating disease outcome. Current Opinion in Immunology 1995 7 485-496.
37. Gorak PMA, Engwerda CR & Kaye PM. Dendritic cells. but not macrophages, produce IL-12 immediately following Leishmania donovani infection. European Journal of Immunology 1998 28 687-695.