메뉴 건너뛰기




Volumn 141, Issue 2, 1999, Pages 180-189

Pharmacological characterisation of a new oral GH secretagogue, NN703

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; HYDROCORTISONE; IBUTAMOREN; TABIMORELIN; TRIPEPTIDE; UNCLASSIFIED DRUG;

EID: 0032779234     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1410180     Document Type: Article
Times cited : (63)

References (38)
  • 1
    • 0001252298 scopus 로고
    • Effects of the enkephalins and enkephalin analogs on release of pituitary hormones in vitro
    • Ed I Maclntyre. Amsterdam: Elsevier/North Holland
    • Bowers CY, Chang J, Momany F & Folkers K. Effects of the enkephalins and enkephalin analogs on release of pituitary hormones in vitro. In Molecular Endocrinology, pp 287-292. Ed I Maclntyre. Amsterdam: Elsevier/North Holland, 1977.
    • (1977) Molecular Endocrinology , pp. 287-292
    • Bowers, C.Y.1    Chang, J.2    Momany, F.3    Folkers, K.4
  • 5
    • 10544241186 scopus 로고    scopus 로고
    • Stimulation of the growth-hormone (GH)-insulin-like growth-factor-I axis by daily oral-administration of a GH secretagogue (MK-677) in healthy elderly subjects
    • Chapman IM, Bach MA, Vancauter E, Farmer M, Krupa D, Taylor AM et al. Stimulation of the growth-hormone (GH)-insulin-like growth-factor-I axis by daily oral-administration of a GH secretagogue (MK-677) in healthy elderly subjects. Journal of Clinical Endocrinology and Metabolism 1996 81 4249-4257.
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , pp. 4249-4257
    • Chapman, I.M.1    Bach, Ma.2    Vancauter, E.3    Farmer, M.4    Krupa, D.5    Taylor, A.M.6
  • 9
    • 0028953390 scopus 로고
    • Intracerebroventricular growth-hormone-releasing-peptide-6 stimulates eating without affecting plasma growth hormone response in rats
    • Locke W, Kirgis HD, Bowers CY & Abdo AA. Intracerebroventricular growth-hormone-releasing-peptide-6 stimulates eating without affecting plasma growth hormone response in rats. Life Sciences 1995 56 1347-1352.
    • (1995) Life Sciences , vol.56 , pp. 1347-1352
    • Locke, W.1    Kirgis, H.D.2    Bowers, C.Y.3    Abdo, A.A.4
  • 10
    • 0029061494 scopus 로고
    • Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol in normal man
    • Friesbo RM, Murck H, Maier P, Schier T, Holsboer F & Steiger A. Growth hormone-releasing peptide-6 stimulates sleep, growth hormone, ACTH and cortisol in normal man. Neuroendocrinology 1995 61 584-589.
    • (1995) Neuroendocrinology , vol.61 , pp. 584-589
    • Friesbo, R.M.1    Murck, H.2    Maier, P.3    Schier, T.4    Holsboer, F.5    Steiger, A.6
  • 11
    • 0021322884 scopus 로고
    • On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone
    • Bowers CY, Momany F, Reynolds GA, Hong A & Newlander K. On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology 1984 114 1537-1545.
    • (1984) Endocrinology , vol.114 , pp. 1537-1545
    • Bowers, C.Y.1    Momany, F.2    Reynolds, G.A.3    Hong, A.4    Newlander, K.5
  • 12
    • 0021368643 scopus 로고
    • Conformational energy studies and in vitro and in vivo activity data on growth hormone releasing peptides
    • Momany FA, Bowers CY, Renolds GA, Hong A & Newlander K. Conformational energy studies and in vitro and in vivo activity data on growth hormone releasing peptides. Endocrinology 1984 114 1531-1536.
    • (1984) Endocrinology , vol.114 , pp. 1531-1536
    • Momany, F.A.1    Bowers, C.Y.2    Renolds, G.A.3    Hong, A.4    Newlander, K.5
  • 20
    • 0024412624 scopus 로고
    • 2 on growth hormone (GH)-releasing factor-stimulated GH release and intracellular adenosine 3′,5′-monophosphate accumulation in rat primary pituitary cell culture
    • 2 on growth hormone (GH)-releasing factor-stimulated GH release and intracellular adenosine 3′,5′-monophosphate accumulation in rat primary pituitary cell culture. Endocrinology 1989 124 2791-2798.
    • (1989) Endocrinology , vol.124 , pp. 2791-2798
    • Cheng, K.1    Chan, W.2    Barreto, A.3    Convey, E.4    Smith, R.G.5
  • 21
    • 0022404614 scopus 로고
    • Structural requirements for the activation of rat anterior pituitary adenylate cyclase by growth hormone-releasing factor (GRF)
    • Robberecht P, Coy DH, Waelbroeck M, Heiman ML, de Neef P, Camus JC & Christophe J. Structural requirements for the activation of rat anterior pituitary adenylate cyclase by growth hormone-releasing factor (GRF). Endocrinology 1985 117 1759-1764.
    • (1985) Endocrinology , vol.117 , pp. 1759-1764
    • Robberecht, P.1    Coy, D.H.2    Waelbroeck, M.3    Heiman, M.L.4    De Neef, P.5    Camus, J.C.6    Christophe, J.7
  • 24
    • 85011457887 scopus 로고    scopus 로고
    • Identification of a pituitary growth hormone-releasing peptide (GHRP) receptor subtype by photoaffinity-labeling
    • Ong H, McNicoll N, Escher E, Collu R, Deghenghi R, Locatelli V et al. Identification of a pituitary growth hormone-releasing peptide (GHRP) receptor subtype by photoaffinity-labeling. Endocrinology 1998 139 432-435.
    • (1998) Endocrinology , vol.139 , pp. 432-435
    • Ong, H.1    McNicoll, N.2    Escher, E.3    Collu, R.4    Deghenghi, R.5    Locatelli, V.6
  • 26
    • 9044228028 scopus 로고    scopus 로고
    • Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585
    • Hickey G, Drisko J, Faidley T, Chang C, Anderson LL, Nicolich S et al. Mediation by the central nervous system is critical to the in vivo activity of the GH secretagogue L-692,585. Journal of Endocrinology 1996 148 371-380.
    • (1996) Journal of Endocrinology , vol.148 , pp. 371-380
    • Hickey, G.1    Drisko, J.2    Faidley, T.3    Chang, C.4    Anderson, L.L.5    Nicolich, S.6
  • 28
    • 0027944106 scopus 로고
    • Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-I, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles
    • Jacks T, Hickey G, Judith F, Taylor J, Chen H, Krupa D et al. Effects of acute and repeated intravenous administration of L-692,585, a novel non-peptidyl growth hormone secretagogue, on plasma growth hormone, IGF-I, ACTH, cortisol, prolactin, insulin, and thyroxine levels in beagles. Endocrinology 1994 143 399-406.
    • (1994) Endocrinology , vol.143 , pp. 399-406
    • Jacks, T.1    Hickey, G.2    Judith, F.3    Taylor, J.4    Chen, H.5    Krupa, D.6
  • 29
    • 0027988189 scopus 로고
    • Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome
    • Leal-Cerro A, Pumar A, Garcia-Garcia E, Dieguez C & Casanueva F. Inhibition of growth hormone release after the combined administration of GHRH and GHRP-6 in patients with Cushing's syndrome. Clinical Endocrinology 1994 41 649-654.
    • (1994) Clinical Endocrinology , vol.41 , pp. 649-654
    • Leal-Cerro, A.1    Pumar, A.2    Garcia-Garcia, E.3    Dieguez, C.4    Casanueva, F.5
  • 30
    • 0030852329 scopus 로고    scopus 로고
    • Effects of GHRP-2 and hexarelin, 2 synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man -comparison with the effects of GHRH, TRH and HCRH
    • Arvat E, Divito L, Maccagno B, Broglio F, Boghen MF, Deghenghi R et al. Effects of GHRP-2 and hexarelin, 2 synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man -comparison with the effects of GHRH, TRH and HCRH. Peptides 1997 18 885-891.
    • (1997) Peptides , vol.18 , pp. 885-891
    • Arvat, E.1    Divito, L.2    Maccagno, B.3    Broglio, F.4    Boghen, M.F.5    Deghenghi, R.6
  • 31
    • 0030967950 scopus 로고    scopus 로고
    • Growth-hormone secretagogues stimulate the hypothalamic-pituitary-adrenal axis and are diabetogenic in the Zucker diabetic fatty rat
    • Clark RG, Thomas GB, Mortensen DL, Won WB, Ma YH, Tomlinson EE et al. Growth-hormone secretagogues stimulate the hypothalamic-pituitary-adrenal axis and are diabetogenic in the Zucker diabetic fatty rat. Endocrinology 1997 138 4316-4323.
    • (1997) Endocrinology , vol.138 , pp. 4316-4323
    • Clark, R.G.1    Thomas, G.B.2    Mortensen, D.L.3    Won, W.B.4    Ma, Y.H.5    Tomlinson, E.E.6
  • 32
    • 0028032110 scopus 로고
    • Efficacy and specificity of L-692,429, a novel nonpeptidyl growth-hormone secretagogue, in beagles
    • Hickey G, Jacks T, Judith F, Taylor J, Schoen WR, Krupa D et al. Efficacy and specificity of L-692,429, a novel nonpeptidyl growth-hormone secretagogue, in beagles. Endocrinology 1994 134 695-701.
    • (1994) Endocrinology , vol.134 , pp. 695-701
    • Hickey, G.1    Jacks, T.2    Judith, F.3    Taylor, J.4    Schoen, W.R.5    Krupa, D.6
  • 33
    • 10144227766 scopus 로고    scopus 로고
    • Effects of a 7-day treatment with a novel, orally-active, growth-hormone (GH) secretagogue, MK-677, on 24-h GH profiles, insulin-like growth-factor-I, and adrenocortical function in normal young men
    • Copinschi G, Vanonderbergen A, Lhermitebaleriaux M, Mendel CM, Caufriez A, Leproult R et al. Effects of a 7-day treatment with a novel, orally-active, growth-hormone (GH) secretagogue, MK-677, on 24-h GH profiles, insulin-like growth-factor-I, and adrenocortical function in normal young men. Journal of Clinical Endocrinology and Metabolism 1996 81 2776-2782.
    • (1996) Journal of Clinical Endocrinology and Metabolism , vol.81 , pp. 2776-2782
    • Copinschi, G.1    Vanonderbergen, A.2    Lhermitebaleriaux, M.3    Mendel, C.M.4    Caufriez, A.5    Leproult, R.6
  • 34
    • 0030743911 scopus 로고    scopus 로고
    • Adrenocorticotropin-releasing and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushings syndrome
    • Ghigo E, Arvat E, Ramunni J, Colao A, Gianotti L, Deghenghi R et al. Adrenocorticotropin-releasing and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushings syndrome. Journal of Clinical Endocrinology and Metabolism 1997 82 2439-2444.
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 2439-2444
    • Ghigo, E.1    Arvat, E.2    Ramunni, J.3    Colao, A.4    Gianotti, L.5    Deghenghi, R.6
  • 36
    • 0032999643 scopus 로고    scopus 로고
    • Growth hormone secretagogues: Physiological role and clinical utility
    • Casanueva FF & Dieguez. Growth hormone secretagogues: Physiological role and clinical utility. Trends in Endocrinology and Metabolism 1999 10 30-38.
    • (1999) Trends in Endocrinology and Metabolism , vol.10 , pp. 30-38
    • Casanueva, F.F.1
  • 38
    • 0030967950 scopus 로고    scopus 로고
    • Growth hormone secretagogues stimulate the hypothalamic-pituitary-adrenal axis and are diabetogenic in the Zucker diabetic fatty rat
    • Clark RG, Thomas GB, Mortensen DL, Won WB, Ma YH, Tomlinson EE et al. Growth hormone secretagogues stimulate the hypothalamic-pituitary-adrenal axis and are diabetogenic in the Zucker diabetic fatty rat. Endocrinology 1997 138 4316-4323.
    • (1997) Endocrinology , vol.138 , pp. 4316-4323
    • Clark, R.G.1    Thomas, G.B.2    Mortensen, D.L.3    Won, W.B.4    Ma, Y.H.5    Tomlinson, E.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.