Cyclization of 2- and 3-indolylthiobenzoic, phenylacetic and nicotinic acids and esters to novel indole-containing tetracyclic ring systems

Journal of Heterocyclic Chemistry

Volumn 36, Issue 3, 1999, Pages 643-652

  Hamel, Pierre ^a   Girard, Mario ^a   Tsou, Nancy N ^b  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID DERIVATIVE; INDOLE DERIVATIVE; NICOTINIC ACID DERIVATIVE; PHENYLACETIC ACID DERIVATIVE;

ARTICLE; CRYSTAL STRUCTURE; CYCLIZATION; REACTION ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0032779197     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570360312     Document Type: Article

References (14)

1. P. Hamel and M. Girard, J. Heterocyclic Chem., 33, 1695 (1996).
2. K. Anzai, J. Heterocyclic Chem., 16, 567 (1979).
3. J. Bourdais and A. Lorre, Eur. J. Med. Chem.-Chim. Ther., 9, 269 (1974).
4. W. C. J. Ross, J. Chem. Soc. (C), 1816 (1966).
5. P. Hamel, N. Zajac, J. G. Atkinson and Y. Girard, J. Org. Chem., 59, 6372 (1994).
6. [a] P. Hamel, Y. Girard and J. G. Atkinson, J. Org. Chem., 57, 2694 (1992);
7. [b] R. Plate and H. C. J. Ottenheijm, Tetrahedron, 42, 4511 (1986).
8. E. Wenkert, J. M. Hanna, Jr., M. H. Leftin, E. L. Michelotti, K. T. Potts and D. Usifer, J. Org. Chem., 50, 1125 (1985).
9. L. F. Fieser and M. Fieser, Reagents for Organic Synthesis, John Wiley and Sons, New York, NY, 1967, Vol 1, p 892.
10. F. Eiden and H. Dobinsky, Leibigs Ann. Chem., 1981 (1974).
11. D. K. Bates and Q. A. Habib, J. Heterocyclic Chem., 32, 1477 (1995).
12. J. G. Atkinson, P. Hamel and Y. Girard, Synthesis, 480 (1988).
13. G. M. Sheldrick, Acta Crystallogr., A46, 467, 1990.
14. G. M. Sheldrick, G. M. SHELXL93, Program for the Refinement of Crystal Structures, University of Göttingen, Germany, 1993.