Expression of a mammalian DNA photolyase confers light-dependent repair activity and reduces mutations of UV-irradiated shuttle vectors in xeroderma pigmentosum cells

Mutation Research - DNA Repair

Volumn 435, Issue 3, 1999, Pages 255-262

  Asahina, Hiroshi ^a   Han, Zhen Bo ^a   Kawanishi, Masanobu ^a   Kato Jr , Tomohisa ^a   Ayaki, Hitoshi ^a   Todo, Takeshi ^a   Yagi, Takashi ^a   Takebe, Hiraku ^a   Ikenaga, Mituo ^a   Kimura, Shinya H ^b  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

CPD photolyase; Expression of photolyase cDNA; Photoreactivation of killing and mutations; supF gene mutations; Xeroderma pigmentosum (XP) cells

Indexed keywords

CYCLOBUTANE DERIVATIVE; DEOXYRIBODIPYRIMIDINE PHOTOLYASE;

ARTICLE; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; GENE MUTATION; HUMAN; HUMAN CELL; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; PHOTOACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHUTTLE VECTOR; XERODERMA PIGMENTOSUM;

BASE SEQUENCE; CELL SURVIVAL; CELLS, CULTURED; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE; DNA MUTATIONAL ANALYSIS; DNA REPAIR; DNA, COMPLEMENTARY; GENETIC VECTORS; HUMANS; LIGHT; MOLECULAR SEQUENCE DATA; MUTATION; PLASMIDS; RNA, MESSENGER; TRANSFECTION; ULTRAVIOLET RAYS; XERODERMA PIGMENTOSUM;

EID: 0032778802     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(99)00051-8     Document Type: Article

References (23)

1. Brash D.E. UV mutagenic photoproducts in Escherichia coli and human cells: a molecular genetics perspective on human skin cancer. Photochem. Photobiol. 48:1988;59-66.
2. Sancar A., Sancar G.B. DNA repair enzymes. Annu. Rev. Biochem. 57:1988;26-67.
3. Wood R.D. DNA repair in eukaryotes. Annu. Rev. Biochem. 65:1996;135-167.
4. Sancar G.B. DNA photolyases: physical properties, action mechanism, and roles in dark repair. Mutat. Res. 236:1990;147-160.
5. Todo T., Takemori H., Ryo H., Ihara M., Matsunaga T., Nikaido O., Sato K., Nomura T. A new photoreactivating enzyme that specifically repairs ultraviolet light-induced (6-4) photoproducts. Nature. 361:1993;371-374.
6. Todo T., Ryo H., Yamamoto K., Toh H., Inui T., Ayaki H., Nomura T., Ikenaga M. Similarity among the Drosophila (6-4)photolyase, a human photolyase homolog, and the DNA photolyase-blue-light photoreceptor family. Science. 272:1996;109-112.
7. Li Y.F., Kim S.-T., Sancar A. Evidence for lack of DNA photoreactivating enzyme in humans. Proc. Natl. Acad. Sci. U.S.A. 90:1993;4389-4393.
8. Kato T. Jr., Todo T., Ayaki H., Ishizaki K., Morita T., Mitra S., Ikenaga M. Cloning of a marsupial DNA photolyase gene and the lack of related nucleotide sequences in placental mammals. Nucleic Acids Res. 22:1994;4119-4124.
9. J.E. Cleaver, K.H. Kraemer, Xeroderma pigmentosum, in: C.R. Scriver, A.L. Beudet, W.S. Sly, D. Valle (Eds.), The Metabolic Basis of Inherited Disease, McGraw-Hill, New York, 1995, pp. 4393-4419.
10. Satokata I., Tanaka K., Miura N., Miyamoto I., Satoh Y., Kondo S., Okada Y. Characterization of a splicing mutation in group A xeroderma pigmentosum. Proc. Natl. Acad. Sci. U.S.A. 87:1990;9908-9912.
11. Takebe H., Nii S., Ishii M.I., Utsumi H. Comparative studies of host-cell reactivation, colony-forming ability and excision repair after UV irradiation of xeroderma pigmentosum, normal human and some other mammalian cells. Mutat. Res. 25:1974;383-390.
12. Chirgwin J.M., Przybyla A.E., MacDonald R.J., Rutter W.J. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
13. Matsunaga T., Mori T., Nikaido O. Base sequence specificity of a monoclonal antibody binding to (6-4)photoproducts. Mutat. Res. 235:1990;187-194.
14. Matsuda T., Yagi T., Kawanishi M., Matsui S., Takebe H. Molecular analysis of mutations induced by 2-chloroacetaldehyde, the ultimate carcinogenic form of vinyl chloride, in human cells using shuttle vectors. Carcinogenesis. 16:1995;2389-2394.
15. P. Armitage, Statistical Methods in Medical Research, Wiley, New York, 1971, pp. 135-138.
16. Zwetsloot J.C.M., Vermeulen W., Hoeijmakers J.H.J., Yasui A., Eker A.P.M., Bootsma D. Microinjected photoreactivating enzymes from Anacystis and Saccharomyces monomerize dimers in chromatin of human cells. Mutat. Res. 146:1985;71-77.
17. Zwetsloot J.C.M., Hoeijmakers J.H.J., Vermeulen W., Eker A.P.M., Bootsma D. Unscheduled DNA synthesis in xeroderma pigmentosum cells after microinjection of yeast photoreactivating enzyme. Mutat. Res. 165:1986;109-115.
18. Protic-Sabljic M., Tuteja N., Munson P.J., Hauser J., Kraemer K.H., Dixon K. UV light-induced cyclobutane pyrimidine dimers are mutagenic in mammalian cells. Mol. Cell. Biol. 6:1986;3349-3356.
19. Bredberg A., Kraemer K.H., Seidman M.M. Restricted ultraviolet mutational spectrum in a shuttle vector propagated in xeroderma pigmentosum cells. Proc. Natl. Acad. Sci. U.S.A. 83:1986;8273-8277.
20. Seetharam S., Kraemer K.H., Waters H.L., Seidman M.M. Abnormal ultraviolet mutagenic spectrum in plasmid DNA replicated in cultured fibroblasts from a patient with skin cancer-prone disease, xeroderma pigmentosum. J. Clin. Invest. 80:1987;1613-1617.
21. Yagi T., Tatsumi-Miyajima J., Sato M., Kraemer K.H., Takebe H. Analysis of point mutations in an ultraviolet-irradiated shuttle vector plasmid propagated in cells from Japanese xeroderma pigmentosum patients in complementation groups A and F. Cancer Res. 51:1991;3177-3182.
22. Yagi T., Sato M., Tatsumi-Miyajima J., Takebe H. UV-induced base substitution mutations in a shuttle vector plasmid propagated in group C xeroderma pigmentosum cells. Mutat. Res. 273:1992;213-220.
23. Levy D.D., Saijo M., Tanaka K., Kraemer K.H. Expression of a transfected DNA repair gene (XPA) in xeroderma pigmentosum group A cells restores normal DNA repair and mutagenesis of UV-treated plasmids. Carcinogenesis. 16:1995;1557-1563.