Neotame: Synthesis, stereochemistry and sweetness

Synthetic Communications

Volumn 29, Issue 24, 1999, Pages 4461-4467

  Prakash, Indra ^a   Bishay, Ihab ^a   Schroeder, Steve ^a  

^a MONSANTO COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTAME; NEOTAME; SWEETENING AGENT; UNCLASSIFIED DRUG;

ARTICLE; HYDROPHILICITY; HYDROPHOBICITY; STEREOCHEMISTRY; STEREOISOMERISM; STRUCTURE ANALYSIS; SYNTHESIS; THREE DIMENSIONAL IMAGING;

EID: 0032778758     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919908086610     Document Type: Article

References (8)

1. Nofri, C. and Tinti, J.-M., US Pat. 5,480,668, 1996; Chem. Abstr. 1996, 112, 235846; Nofri, C. and Tinti, J.-M., US Pat. 5,510,508, 1996; Chem. Abstr. 1996, 112, 235846.
2. Nofri, C. and Tinti, J.-M., US Pat. 5,480,668, 1996; Chem. Abstr. 1996, 112, 235846; Nofri, C. and Tinti, J.-M., US Pat. 5,510,508, 1996; Chem. Abstr. 1996, 112, 235846.
3. Nofri, C. and Tinti, J.-M., US Pat. 5,480,668, 1996; Chem. Abstr. 1996, 112, 235846; Nofri, C. and Tinti, J.-M., US Pat. 5,510,508, 1996; Chem. Abstr. 1996, 112, 235846.
4. Nofri, C. and Tinti, J.-M., US Pat. 5,480,668, 1996; Chem. Abstr. 1996, 112, 235846; Nofri, C. and Tinti, J.-M., US Pat. 5,510,508, 1996; Chem. Abstr. 1996, 112, 235846.
5. 0) and 0.0806 for all data measurements acquired. A water molecule was also present in the unit cell as a hydrate molecule of L,L-α-Neotame.
6. Goodman, M. et al., J. Pep. Sci. 1998, 4, 229.
7. Mazur, R. H.; Goldkamp, A. H.; James, P. A. and Schlatter, J. M. J. Med. Chem. 1970, 13, 1217.
8. Mazur, R. H., Symposium: Sweetener.; Inglett G. E., Ed.; Avi Publishing Co.; Westport, CT, 1974; p159.