Effects of activation of renal adenosine A2 receptor on renal function and renin release in dogs

Japanese Journal of Pharmacology

Volumn 80, Issue 2, 1999, Pages 173-176

  Miura, Katsuyuki ^a   Okumura, Michiaki ^b   Yamanaka, Shinya ^a   Kim, Shokei ^a   Iwao, Hiroshi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA CITY GENERAL HOSPITAL   (Japan)

Author keywords

Adenosine; Adenosine A2 receptor; Renal hemodynamics

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2 RECEPTOR; PROPRANOLOL; RENIN;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ARTERIOLE; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DOG; GLOMERULUS FILTRATION RATE; INTRAARTERIAL DRUG ADMINISTRATION; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY PERFUSION; MICTURITION; NONHUMAN; PERFUSION PRESSURE; RENIN RELEASE; TACHYCARDIA; VASODILATATION;

EID: 0032777101     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.80.173     Document Type: Article

References (12)

1. Zou Ap, Wu F, Li PL and Cowley AW Jr: Effect of chronic salt loading on adenosine metabolism and receptor expression in renal cortex and medulla in rats. Hypertension 33, 511-516 (1999)
2. Spielman WS and Thompson CI: A proposed role for adenosine in the regulation of renal hemodynamics and renin release. Am J Physiol 242, F423-F435 (1982)
3. Aki Y, Shoji T, Hasui K, Fukui K, Tamaki T, Iwao H and Abe Y: Intrarenal vascular sites of action of adenosine and glucagon. Jpn J Pharmacol 54, 433-440 (1990)
4. Spielman WS and Arend LJ: Adenosine receptors and signaling in the kidney. Hypertension 17, 117-130 (1991)
5. Arakawa K, Suzuki H, Naitoh M, Matsumoto A, Hayashi K, Matsuda H, Ichihara A, Kubota E and Saruta T: Role of adenosine in the renal responses to contrast medium. Kidney Int 49, 1199-1206 (1996)
6. Hutchison AJ, Webb RL, Oei HH, Ghai GR, Zimmerman MB and Williams M: CGS21680C, an A2 selective adenosine receptor agonist with preferential hypotensive activity. J Pharmacol Exp Ther 251, 47-55 (1989)
7. Levens N, Beil M and Jarvis M: Renal actions of a new adenosine agonist, CGS 21680A selective for the A2 receptor. J Pharmacol Exp Ther 257, 1005-1012 (1991)
8. Levens N, Beil M and Schulz R: Intrarenal actions of the new adenosine agonist CGS 21680A, selective for the A2 receptor. J Pharmacol Exp Ther 257, 1013-1019 (1991)
9. Abe Y, Dixon F and McNay JL: Dissociation between autoregulation of renal blood flow and glomerular filtration rate. Am J Physiol 119, 986-993 (1970)
10. Panzacchi G, Demarchi B, Busca G, Protasoni G, Golin R and Stella A: Effects of adenosine receptor agonists on renal function in anaesthetized rats. J Hypertens 15, 1785-1789 (1997)
11. Churchill PC and Bidani A: Renal effects of selective adenosine receptor agonists in anesthetized rats. Am J Physiol 252, F299-F303 (1987)
12. Keeton TK and Campbell WB: The pharmacologic alteration of renin release. Pharmacol Rev 32, 81-227 (1980)