Immunolocalization and quantitation of transforming growth factor alpha in hydatidiform mole

Tumori

Volumn 85, Issue 3, 1999, Pages 183-187

  Molykutty, John ^a   Schultz, Gregory ^b   Rajalekshmy, T Nellika ^c   Enose, Swapna ^a   Nair, M Krishnan ^a   Balaram, Prabha ^a,d  

^a GOVERNMENT MEDICAL COLLEGE   (India)

^b Institute for Wound Research   (United States)

^c Medical College Hospital Thiruvananthapuram   (India)

^d REGIONAL CANCER CENTRE   (India)

Author keywords

Decidua; Hydatidiform mole; Transforming growth factor ; Trophoblasts

Indexed keywords

AVIDIN; BIOTIN; CHROMOGENIC SUBSTRATE; MONOCLONAL ANTIBODY; PARAFFIN; PEROXIDASE; TRANSFORMING GROWTH FACTOR ALPHA;

ARTICLE; CHORIOCARCINOMA; CONTROLLED STUDY; CYTOTROPHOBLAST; DECIDUA; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; HYDATIDIFORM MOLE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PLACENTA; PROTEIN LOCALIZATION; SYNCYTIOTROPHOBLAST; TROPHOBLASTIC TUMOR;

EID: 0032776517     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089169908500307     Document Type: Article

References (18)

1. Anzano M.A., Roberts A.B., Smith J.M., Sporn M.B., De Larco J.E.: Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type α and type transforming growth factors. Proc. Natl. Acad. Sci., 80: 6264, 1983.
2. Balaram P., Molykutty J., Rajalekshmy T.N., Balaraman Nair, Schultz G., Krishnan Nair M.: Expression of epidermal growth factor receptor in gestational trophoblastic diseases. J. Cancer Res. Clin. Oncol., 123: 161-166, 1997.
3. Bisonnette F., Cook C., Geophegan T., Steffen M., Henry J., Yassman M.A., Schultz G.: Transforming growth factor α and epidermal growth factor messenger ribonucleic acid and protein levels in human placentae from early, mid and late gestation. Am. J. Obstet. Gynecol., 166: 192-199, 1992.
4. Darlak K., Franklin G., Woost P., Sonnerfeld E., Twardzix D., Spatia A., Schultz G.: Assessment of biological activity of synthetic fragments of transforming growth factor alpha. J. Cell. Biochem., 36: 341-352, 1988.
5. De Larco J.E., Todaro G.J.: Growth factors from murine sarcoma virus-transformed cells. Proc. Natl. Acad. Sci. USA, 75: 4001-4005, 1978.
6. Derynck R., Jarret J.A., Chen E.Y., Eaton D.H., Bell J.R., Assoian R.K., Roberts A.B., Sporn M.B.: Human transforming growth factor - complementary DNA sequence and expression in normal and transformed cells. Nature, 316: 701-705, 1985.
7. Derynck R., Goeddel D.V., Ullrich A., Gutterman J.U., Williams R.D., Bringman T.S., Berger W.H.: Synthesis of mRNAs for transforming growth factors-α and the epidermal growth factor by human tumors. Cancer Res., 47: 707, 1987.
8. Derynck R: Transforming growth factor α. Cell, 54: 593-595, 1988.
9. Doreen M.S.: The gestational trophoblastic diseases: a review of their presentation and management. Clin. Oncol., 3: 40-50, 1993.
10. Filla M.S., Zhang C.D., Kaul K.L.: A potential transforming growth factor α/epidermal growth factor receptor autocrine circuit in placental cytotrophoblasts. Cell Growth Differ., 4: 387-393, 1993.
11. Fox S.B., Smith K., Hollyer J., Greenall M., Hastrich D., Harris A.L.: The epidermal growth factor receptor as a prognostic marker: results of 370 patients and review of 3009 patients. Breast Cancer Res. Treat., 29: 41-49, 1994.
12. Haining R.E.B., Schofield J.P., Jones D.S.C., Rajput-Williams J., Smith S.K.: Identification of mRNA for epidermal growth factor and transforming growth factor-α in low copy number in human endometrium and decidua using reverse transcriptase-polymerase chain reaction. J. Mol. Endocrinol., 6: 207-204, 1991.
13. Han V.K., Hunter E.S., Pratt R.M., Zendegui J.G., Lee D.C.: Expression of rat transforming growth factor alpha mRNA during development occurs predominantly in the maternal decidua. Mol. Cell. Biol., 7: 2335-2343, 1987.
14. Lysiak J.J., Han V.K.M., Lala P.K.: Localization of transforming growth factor-α (TGF-α) in the human placenta and decidua: role in trophoblast growth. Biol. Reprod., 49: 885-894, 1993.
15. Lysiak J.J., Connelly I.H., Khoo W.K.S., Stetler-Stevenson W., Lala P.K.: Role of transforming growth factor α (TGF-α) and epidermal growth factor (EGF) on proliferation and invasion by first trimester human trophoblast. Troph. Res., 8: 455-467, 1994.
16. Mühlhauser J., Crescimanno C., Kaufmann P., Höfler H., Zaccheo D., Castellucci M.: Differentiation and proliferation patterns in human trophoblasts revealed by c-erb-2 oncogene product and EGFR. J. Histochem. Cytochem., 41: 165-173, 1993.
17. Pike L.U., Marquardt H., Todaro G.J., Gallis B., Casnellie J.E., Bornstein P., Krebs E.G.: Transforming growth factor and epidermal growth factor stimulate the phosphorylation of a synthetic, tyrosine-containing peptide in similar manner. J. Biol. Chem., 257: 14628-14631, 1982.
18. Prigent S.A., Lemoine N.R.: The type 1 (EGFR-related) family of growth factor receptors and their ligands. Prog. Growth Factor Res., 4: 1-24, 1992.