Time course of serum neuron-specific enolase: A predictor of neurological outcome in patients resuscitated from cardiac arrest

Stroke

Volumn 30, Issue 8, 1999, Pages 1598-1603

  Schoerkhuber, Waltraud ^b   Kittler, Harald ^b   Sterz, Fritz ^a   Behringer, Wilhelm ^b   Holzer, Michael ^b   Frossard, Martin ^b   Spitzauer, Susanne ^b   Laggner, Anton N ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b NONE

Author keywords

Cardiopulmonary resuscitation; Heart arrest; Neuron specific enolase; Outcome

Indexed keywords

NEURON SPECIFIC ENOLASE;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; DISABILITY; DISEASE COURSE; EMERGENCY TREATMENT; ENZYME ASSAY; FEMALE; HEART ARREST; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROLOGICAL COMPLICATION; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROGNOSIS; RESUSCITATION;

EID: 0032776399     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.30.8.1598     Document Type: Article

References (53)

1. Martens P, Haymerle A, Sterz, F, Vanhaute O, Calle P. Limitation of life support after resuscitation from cardiac arrest: practice in Belgium and Austria. Resuscitation. 1997;35:123-128.
2. Jacobs P, Noseworthy TW. National estimates of intensive care utilization and costs: Canada and the United States. Crit Care Med. 1990;18: 1282-1286.
3. Levy DE, Bates D, Caronna JJ, Cartlidge NE, Knill Jones RP, Lapinsky RH, Singer BH, Shaw DA, Plum F. Prognosis in nontraumatic coma. Ann Intern Med. 1981;94:293-301.
4. Longstreth WT Jr, Diehr P, Inui TS. Prediction of awakening after out-of-hospital cardiac arrest. N Engl J Med. 1983;308:1378-1382.
5. Levy DE, Caronna JJ, Singer BH, Lapinski RH, Frydman H, Plum F. Predicting outcome from hypoxic-ischemic coma. JAMA. 1985;253: 1420-1426.
6. Mullie A, Verstringe P, Buylaert W, Houbrechts H. Michem N, Delooz H, Verbruggen H, Van den Broeck L, Come L, Lauwaert D, for the Cerebral Resuscitation Study Group of the Belgian Society for Intensive Care. Predictive value of Glasgow Coma Score for awakening after out-of-hospital cardiac arrest. Lancet. 1988;1:137-140.
7. Scollo Lavizzari G, Bassetti C. Prognostic value of EEG in post-anoxic coma after cardiac arrest. Eur Neurol. 1987;26:161-170.
8. Brunko E, Zegers de Beyl D. Prognostic value of early cortical somato-sensory evoked potentials after resuscitation from cardiac arrest. Electroencephalogr Clin Neurophysiol. 1987;66:15-24.
9. Rothstein TL, Thomas EM, Sumi SM. Predicting outcome in hypoxic-ischemic coma: a prospective clinical and electrophysiologic study. Electroencephalogr Clin Neurophysiol. 1991;79:101-107.
10. Zentner J, Rohde V. The prognostic value of somatosensory and motor evoked potentials in comatose patients. Neurosurgery. 1992;31:429-434.
11. Madl C, Grimm G, Kramer L, Yeganehfar W, Sterz F, Schneider B, Kranz A, Schneeweiss B, Lenz K. Early prediction of individual outcome after cardiopulmonary resuscitation. Lancet. 1993;341:855-858.
12. Kjos BO, Brant Zawadzki M, Young RG. Early CT findings of global central nervous system hypoperfusion. AJR Am J Roentgenol. 1983;141: 1227-1232.
13. Roine RO, Raininko R, Erkinjuntti T, Ylikoski A, Kaste M. Magnetic resonance imaging findings associated with cardiac arrest. Stroke. 1993; 24:1005-1014.
14. Morimoto Y, Kemmotsu O, Kitami K, Matsubara I, Tedo I. Acute brain swelling after out-of-hospital cardiac arrest: pathogenesis and outcome. Crit Care Med. 1993;21:104-110.
15. Fujioka M, Okuchi K, Sakaki T, Hiramatsu K, Miyamoto S, Iwasaki S. Specific changes in human brain following reperfusion after cardiac arrest. Stroke. 1994;25:2091-2095.
16. Berek K, Lechleitner P, Luef G, Felber S, Saltuari L, Schinnerl A, Traweger C, Dienstl F, Aichner F. Early determination of neurological outcome after prehospital cardiopulmonary resuscitation. Stroke. 1995; 26:543-549.
17. Rupright J, Woods EA, Singh A. Hypoxic brain injury: evaluation by single photon emission computed tomography. Arch Phys Med Rehabil. 1996;77:1205-1208.
18. Roine RO, Somer H, Kaste M, Viinikka L, Karonen SL. Neurological outcome after out-of-hospital cardiac arrest: prediction by cerebrospinal fluid enzyme analysis. Arch Neurol. 1989;46:753-756.
19. Karkela J, Pasanen M, Kaukinen S, Morsky P, Harmoinen A. Evaluation of hypoxic brain injury with spinal fluid enzymes, lactate, and pyruvate. Crit Care Med. 1992;20:378-386.
20. Vaagenes P, Mullie A, Fodstad DT, Abramson N, Safar P, for the Brain Resuscitation Clinical Trial I Study Group. The use of cytosolic enzyme increase in cerebrospinal fluid of patients resuscitated after cardiac arrest. Am J Emerg Med. 1994;12:621-624.
21. Schmechel D, Marangos PJ, Zis AP, Brightman M, Goodwin FK. Brain enolases as specific markers of neuronal and glial cells. Science. 1978; 199:313-315.
22. Marangos PJ, Schmechel D, Parma AM, Clark RL, Goodwin FK. Measurement of neuron-specific (NSE) and non-neuronal (NNE) isoenzymes of enolase in rat, monkey and human nervous tissue. J Neurochem. 1979;33:319-329.
23. Marangos PJ, Schmechel DE. Neuron specific enolase, a clinically useful marker for neurons and neuroendocrine cells. Annu Rev Neurosci. 1987; 10:269-295.
24. Francis A, Rivett AJ, Roth JA. Activity of neuron-specific enolase in normal and lesioned rat brain. Brain Res. 1983;263:89-95.
25. Steinberg R, Gueniau C, Scarna H, Keller A, Worcel M, Pujol JF. Experimental brain ischemia: neuron-specific enolase level in cerebrospinal fluid as an index of neuronal damage. J Neurochem. 1984;43: 19-24.
26. Hans P, Bonhomme V, Collette J, Moonen G. Neuron-specific enolase as a marker of in vitro neuronal damage, part I: assessment of neuron-specific enolase as a quantitative and specific marker of neuronal damage. J Neurosurg Anesthesiol. 1993;5:111-116.
27. Schmechel D, Marangos PJ, Brightman M. Neurone-specific enolase is a molecular marker for peripheral and central neuroendocrine cells. Nature. 1978;276:834-836.
28. D'Alessandro M, Mariani P, Lomanto D, Carlei F, Lezoche E, Speranza V. Serum neuron-specific enolase in diagnosis and follow-up of gastrointestinal neuroendocrine tumors. Tumour Biol. 1992;13:352-357.
29. Zeltzer PM, Marangos PJ, Evans AE, Schneider SL. Serum neuron-specific enolase in children with neuroblastoma: relationship to stage and disease course. Cancer. 1986;57:1230-1234.
30. Ladenstein R, Urban C, Gadner H, Fink FM, Zoubek A, Emminger W, Grienberger H, Schmitt K, Ambros PF, Ambros IM. First experience with prognostic factors in unselected neuroblastoma patients: the Austrian Neuroblastoma 87 Study. Eur J Cancer. 1995;31a:637-641.
31. Burghuber OC, Worofka B, Schernthaner G, Vetter N, Neumann M, Dudczak R, Kuzmits R. Serum neuron-specific enolase is a useful tumor marker for small cell lung cancer. Cancer. 1990;65:1386-1390.
32. Fizazi K, Cojean I, Pignon JP, Rixe O, Gatineau M, Hadef S, Arriagada R, Baldeyrou P, Comoy E, Le Chevalier T. Normal serum neuron specific enolase (NSE) value after the first cycle of chemotherapy: an early predictor of complete response and survival in patients with small cell lung carcinoma. Cancer. 1998;82:1049-1055.
33. Cunningham RT, Young IS, Winder J, MJ OK, McKinstry S, Johnston CF, Dolan OM, Hawkins SA, Buchanan KD. Serum neurone specific enolase (NSE) levels as an indicator of neuronal damage in patients with cerebral infarction. Eur J Clin Invest. 1991;21:497-500.
34. Barone FC, Clark RK, Price WJ, White RF, Feuerstein GZ, Storer BL, Ohlstein EH. Neuron-specific enolase increases in cerebral and systemic circulation following focal ischemia. Brain Res. 1993;623:77-82.
35. Cunningham RT, Watt M, Winder J, McKinstry S, Lawson JT, Johnston CF, Hawkins SA, Buchanan KD. Serum neurone-specific enolase as an indicator of stroke volume. Eur J Clin Invest. 1996;26:298-303.
36. Mabe H, Suzuki S, Mase M, Umemura A, Nagai H. Serum neuron-specific enolase levels after subarachnoid hemorrhage. Surg Neurol. 1991;36:170-174.
37. Skogseid IM, Nordby HK, Urdal P, Paus E, Lilleaas F. Increased serum creatine kinase BB and neuron specific enolase following head injury indicates brain damage. Acta Neurochir (Wien). 1992;115:106-111.
38. Isgro F, Schmidt C, Pohl P, Saggau W. A predictive parameter in patients with brain related complications after cardiac surgery? Eur J Cardiothorac Surg. 1997;11:640-644.
39. Persson L, Hardemark HG, Gustafsson J, Rundstrom G, Mendel Hartvig I, Esscher T, Pahlman S. S-100 protein and neuron-specific enolase in cerebrospinal fluid and serum: markers of cell damage in human central nervous system. Stroke. 1987;18:911-918.
40. Schaarschmidt H, Prange HW, Reiber H. Neuron-specific enolase concentrations in blood as a prognostic parameter in cerebrovascular diseases. Stroke. 1994;25:558-565.
41. Dauberschmidt R, Zinsmeyer J, Mrochen H, Meyer M. Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation. Mol Chem Neuropathol. 1991;14:237-245.
42. Horn M, Seger F, Schlote W. Neuron-specific enolase in gerbil brain and serum after transient cerebral ischemia. Stroke. 1995;26:290-296.
43. Stelzl T, von Bose MJ, Hogl B, Fuchs HH, Flugel KA. A comparison of the prognostic value of neuron-specific enolase serum levels and somato-sensory evoked potentials in 13 reanimated patients. Eur J Emerg Med. 1995;2:24-27.
44. Martens P, Raabe A, Johnsson P. Serum S-100 and neuron-specific enolase for prediction of regaining consciousness after global cerebral ischemia. Stroke. 1998;29:2363-2366.
45. Fogel W, Krieger D, Veith M, Adams HP, Hund E, Storch-Hagenlocher B, Buggle F, Mathias D, Hacke W. Serum neuron-specific enolase as early predictor of outcome after cardiac arrest. Crit Care Med. 1997;25: 1133-1138.
46. Cummins RO, Chamberlain DA, Abramson NS, Allen M, Baskett PJ, Becker L, Bossaert L, Delooz HH, Dick WF, Eisenberg MS. Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the Utstein Style: a statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council. Circulation. 1991;84:960-975.
47. American Heart Association. Standards and guidelines for cardiopulmonary resuscitation and emergency cardiac care. JAMA. 1992;268: 2205-2211.
48. Royds JA, Davies Jones GA, Lewtas NA, Timperley WR, Taylor CB. Enolase isoenzymes in the cerebrospinal fluid of patients with diseases of the nervous system. J Neurol Neurosurg Psychiatry. 1983;46:1031-1036.
49. Cunningham RT, Morrow JI, Johnston CF, Buchanan KD. Serum neurone-specific enolase concentrations in patients with neurological disorders. Clin Chim Acta. 1994;230:117-124.
50. Marangos PJ, Campbell IC, Schmechel DE, Murphy DL, Goodwin FK. Blood platelets contain a neuron-specific enolase subunit. J Neurochem. 1980;34:1254-1258.
51. Brown KW, Kynoch PA, Thompson RJ. Immunoreactive nervous system of specific enolase (14-3-2 protein) in human serum and cerebrospinal fluid. Clin Chim Acta. 1980;101:257-264.
52. Fauvage B, Combes P. Isoelectric electroencephalogram and loss of evoked potentials in a patient who survived cardiac arrest. Crit Care Med. 1993;21:472-475.
53. Schmitt B, Simma B, Burger R, Dumermuth G. Resuscitation after severe hypoxia in a young child: temporary isoelectric EEG and loss of BAEP components. Intensive Care Med. 1993;19:420-422.