Inhaled nitric oxide does not alter pulmonary or cardiac effects of fat embolism in dogs after cemented arthroplasty

Canadian Journal of Anaesthesia

Volumn 46, Issue 6, 1999, Pages 605-612

  Byrick, Robert J ^a   Mullen, J Brendan ^b   Murphy, Patricia M ^b   Kay, J Colin ^b   Stewart, Thomas E ^b   Edelist, Gerald ^b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHROPLASTY; ARTICLE; BLOOD VESSEL DIAMETER; CARDIOPULMONARY HEMODYNAMICS; CONTROLLED STUDY; DOG; DRUG EFFECT; FAT EMBOLISM; HEART DILATATION; HEART RIGHT VENTRICLE VOLUME; INHALATION ANESTHESIA; LUNG ARTERY PRESSURE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY OCCLUSION; PULMONARY HYPERTENSION; TRANSESOPHAGEAL ECHOCARDIOGRAPHY;

EID: 0032775432     PISSN: 0832610X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03013555     Document Type: Article

References (21)

1. Ereth MH, Weber JG, Abel MD, et al. Cemented versus noncemented total hip arthroplasty - embolism, hemo-dynamics, and intrapulmonary shunting. Mayo Clin Pro 1992; 67: 1066-74.
2. Fitzgerald R, Mason L, Kanumilli V, Kleinhomer K, Sakamoto A, Johnson C. Transient cardiac standstill associated with embolic phenomena diagnosed by introperative transesophageal echocardiography during cemented total hip arthroplasty. Anesth Analg 1994; 79: 382-5.
3. Pell ACH, Christie J, Keating JF, Sutherland GR. The detection of fat embolism by transoesophageal echocardiography during reamed intramedullary nailing. A study of 24 patients with femoral and tibial fractures. J Bone Joint Surg 1993; 75-B: 921-5.
4. Urban MK, Sheppard R, Gordon MA, Urquhart BL. Right ventricular function during revision total hip arthroplasty. Anesth Analg 1996; 82: 1225-9.
5. Propst JW, Siegel LC, Schnittger I, Foppiano L, Goodman SB, Brock-Utne JG. Segmental wall motion abnormalities in patients undergoing total hip replacement: correlations with intraoperative events. Anesth Analg 1993; 77: 743-9.
6. Pietak S, Holmes J, Matthews R, Petrasek A, Porter B. Cardiovascular collapse following femoral prosthesis surgery for acute hip fracture. Can J Anaesth 1997; 44: 198-201.
7. Murphy P, Edelist G, Byrick RJ, Kay JC, Mullen JB. Relationship of fat embolism to haemodynamic and echocardiographic changes during cemented arthroplasty. Can J Anaesth 1997; 44: 1293-300.
8. Byrick RJ, Mullen JB, Mazer CD, Guest CB. Transpulmonary systemic fat embolism. Studies in mongrel dogs after cemented arthroplasty. Am J Respir Crit Care Med 1994; 150: 1416-22.
9. Rossaint R, Falke KF, Lopez F, Slama K, Pison U, Zapol WM. Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 1993; 328: 399-405.
10. Pison U, Lopez FA, Heidelmeyer CF, Rossaint R, Falke KJ. Inhaled nitric oxide reverses hypoxic pulmonary vasoconstriction without impairing gas exchange. J Appl Physiol 1993; 74: 1287-92.
11. Stewart TE, Valenza F, Ribeiro SP, et al. Increased nitric oxide in exhaled gas as an early marker of lung inflammation in a model of sepsis. Am J Respir Crit Care Med 1995; 151: 713-8.
12. Vedrinne JM, Curtil A, Martinot S, et al. The hemodynamic effects of hypoxemia in anesthetized pigs: a comparison between right heart catheter and echocardiography. Anesth Analg 1998; 87: 21-6.
13. Treggiari-Venzi M, Ricou B, Romand J-A, Suter PM. The response to repeated nitric oxide inhalation is inconsistent in patients with acute respiratory distress syndrome. Anesthesiology 1998; 88: 634-41.
14. Manktelow C, Bigatello LM, Hess D, Hurford WE. Physiologic determinants of the response to inhaled nitric oxide in patients with acute respiratory distress syndrome. Anesthesiology 1997; 87: 297-307.
15. Galinier M, Rougé P, Fourcade J, et al. Lack of haemodynamic effects of nitric oxide on post-capillary pulmonary hypertension induced by acute sino-aortic denervation. Br J Pharmacol 1997; 120: 7-12.
16. Mélot C, Vermeulen F, Maggiorini M, Gilbert E, Naeije R. Site of pulmonary vasodilation by inhaled nitric oxide in microembolic lung injury. Am J Respir Grit Care Med 1997; 156: 75-85.
17. Orsini EC, Byrick RJ, Mullen JBM, Kay JC, Waddell JP. Cardiopulmonary function and pulmonary microemboli during arthroplasty using cemented or non-cemented components. J Bone Joint Surg 1987; 69A: 822-32.
18. Hopkins SR, Johnson EC, Richardson RS, Wagner H, De Rosa M, Wagner PD. Effects of inhaled nitric oxide on gas exchange in lungs with shunt or poorly ventilated areas. Am J Respir Crit Care Med 1997; 156: 484-91.
19. Young I, Mazzone RW, Wagner PD. Identification of functional lung unit in the dog by graded vascular embolization. J Appl Physiol 1980; 49: 132-41.
20. Fahmy NR, Head CA, Nathan N, Zafol WM. Inhaled nitric oxide reverses acute pulmonary hypertension and hypoxemia during orthopedic procedures. Anesthesiology 1997; 87: A1120.
21. Byrick RJ, Forbes D, Waddell JP. A monitored cardiovascular collapse during cemented total knee replacement. Anesthesiology 1986; 65: 213-6.