The uptake of fluoroquinolone agent drugs by cultured human conjunctival epithelial cells and cultured SIRC rabbit corneal cells

Journal of Japanese Ophthalmological Society

Volumn 103, Issue 8, 1999, Pages 576-579

  Fukuda, Masamichi ^a   Yoshitake, Yoshino ^a   Sasaki, Kazuyuki ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Cultured human conjunctival epithelial cell line (HCEC); Cultured rabbit cornea cell lines (SIRC); Fluoroquinolone; Intraocular drug dynamics; Uptake of drugs

Indexed keywords

LOMEFLOXACIN; NORFLOXACIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONJUNCTIVA EPITHELIUM; CORNEA CELL; DRUG SCREENING; DRUG UPTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN;

ANIMALS; ANTI-INFECTIVE AGENTS; CELLS, CULTURED; CONJUNCTIVA; CORNEA; EPITHELIAL CELLS; FLUOROQUINOLONES; HUMANS; NORFLOXACIN; OFLOXACIN; QUINOLONES; RABBITS;

EID: 0032775183     PISSN: 00290203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Fukuda M, Sasaki K: Intraocular dynamic mode differences of new quinolone antibacterial agents between pigmented and albino rabbit eyes. Lens Eye Toxic Res 6: 339-351, 1989.
2. Fukuda M, Sasaki K, Tsuzuki H, Takahashi N: Intraocular dynamics of β-lactam (CMX) in combination with aminoglycoside. Proceedings of the 14th International Congress of Chemotherapy. Kyoto, 1985.
3. Schoenwald RD: Ocular drug delivery. Pharmacokinetic considerations. Clin Pharmacokinet 18: 255-269, 1990.