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Volumn 127, Issue 3, 1999, Pages 321-327

Effects of GABA-transaminase inhibition on brain metabolism and amino-acid compartmentation: An in vivo study by 2D 1H-NMR spectroscopy coupled with microdialysis

Author keywords

Amino acids; Compartmentation; Gabaculine; Microdialysis; NMR spectroscopy

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRATE AMINOTRANSFERASE INHIBITOR; 4 AMINOBUTYRIC ACID; ASPARTIC ACID; EXCITATORY AMINO ACID; GABACULINE; GLUTAMIC ACID; NEUROTRANSMITTER;

EID: 0032773560     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002210050802     Document Type: Article
Times cited : (29)

References (29)
  • 2
    • 4243352368 scopus 로고
    • NMR measurement of GABA in vivo following gabaculine administration
    • Behar KL, Boehm D (1991) NMR measurement of GABA in vivo following gabaculine administration. J Cereb Blood Flow Metab 11:S783
    • (1991) J Cereb Blood Flow Metab , vol.11
    • Behar, K.L.1    Boehm, D.2
  • 3
    • 0009577380 scopus 로고
    • Surface coil techniques for "in vivo" NMR
    • Bendall MR (1986) Surface coil techniques for "in vivo" NMR. Bull Magn Reson 8:17-42
    • (1986) Bull Magn Reson , vol.8 , pp. 17-42
    • Bendall, M.R.1
  • 4
    • 0026451073 scopus 로고
    • The effect of sodium valproate on extracellular GABA and other amino acids in the rat ventral hippocampus: An in vivo microdialysis study
    • Biggs CS, Pearce BR, Fowler LJ, Whitton PS (1992) The effect of sodium valproate on extracellular GABA and other amino acids in the rat ventral hippocampus: an in vivo microdialysis study. Brain Res 594:138-142
    • (1992) Brain Res , vol.594 , pp. 138-142
    • Biggs, C.S.1    Pearce, B.R.2    Fowler, L.J.3    Whitton, P.S.4
  • 5
    • 0002159798 scopus 로고
    • GABA and glycine
    • Siegel GJ, Agranoff BW, Alberts RW, Molinoff PB (eds). Raven Press, New-York
    • De Lorey TM, Olsen RW (1994) GABA and glycine. In: Siegel GJ, Agranoff BW, Alberts RW, Molinoff PB (eds) Basic neurochemistry, 5th edn. Raven Press, New-York, pp 389-399
    • (1994) Basic Neurochemistry, 5th Edn. , pp. 389-399
    • De Lorey, T.M.1    Olsen, R.W.2
  • 6
    • 0026709603 scopus 로고
    • The γ-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats
    • Fink-Jensen A, Suzdak PD, Swedberg MDB, Judge ME, Hansen L, Nielsen PG (1992) The γ-aminobutyric acid (GABA) uptake inhibitor, tiagabine, increases extracellular brain levels of GABA in awake rats. Eur J Pharmacol 220:197-201
    • (1992) Eur J Pharmacol , vol.220 , pp. 197-201
    • Fink-Jensen, A.1    Suzdak, P.D.2    Swedberg, M.D.B.3    Judge, M.E.4    Hansen, L.5    Nielsen, P.G.6
  • 7
    • 0001550549 scopus 로고
    • A preparative synthesis of D, L-gabaculine
    • François JP, Gittos MW (1979) A preparative synthesis of D, L-gabaculine. Synth Comm 9:741-750
    • (1979) Synth Comm , vol.9 , pp. 741-750
    • François, J.P.1    Gittos, M.W.2
  • 8
    • 0025054163 scopus 로고
    • Endogenous release of γ-aminobutyric acid from the medial preoptic area measured by microdialysis in the anaesthetised rat
    • Herbison AE, Heavens RP, Dyer RG (1990) Endogenous release of γ-aminobutyric acid from the medial preoptic area measured by microdialysis in the anaesthetised rat. J Neurochem 55:1617-1623
    • (1990) J Neurochem , vol.55 , pp. 1617-1623
    • Herbison, A.E.1    Heavens, R.P.2    Dyer, R.G.3
  • 9
    • 0027050085 scopus 로고
    • Acute effects of γ-vinyl GABA on the GABAergic system in rats as studied by microdialysis
    • Jolkkonen J, Mazurkiewicz M, Lahtinen H, Riekkinen P (1992) Acute effects of γ-vinyl GABA on the GABAergic system in rats as studied by microdialysis. Eur J Pharmacol 229:269-272
    • (1992) Eur J Pharmacol , vol.229 , pp. 269-272
    • Jolkkonen, J.1    Mazurkiewicz, M.2    Lahtinen, H.3    Riekkinen, P.4
  • 10
    • 0017553966 scopus 로고
    • γ-vinyl-GABA (4-amino-hex-5-enoic acid), a new selective irreversible inhibitor of GABA-T: Effects on brain GABA metabolism in mice
    • Jung MJ, Lippert B, Metcalf BW, Böhlen P, Schechter PJ (1977) γ-vinyl-GABA (4-amino-hex-5-enoic acid), a new selective irreversible inhibitor of GABA-T: effects on brain GABA metabolism in mice. J Neurochem 29:797-802
    • (1977) J Neurochem , vol.29 , pp. 797-802
    • Jung, M.J.1    Lippert, B.2    Metcalf, B.W.3    Böhlen, P.4    Schechter, P.J.5
  • 11
    • 0025006641 scopus 로고
    • Preferential release of neuroactive amino acids from the ventrolateral medulla of the rat in vivo as measured by microdialysis
    • Kapoor V, Nakahara D, Blood RJ, Chalmers JP (1990) Preferential release of neuroactive amino acids from the ventrolateral medulla of the rat in vivo as measured by microdialysis. Neuroscience 37:187-191
    • (1990) Neuroscience , vol.37 , pp. 187-191
    • Kapoor, V.1    Nakahara, D.2    Blood, R.J.3    Chalmers, J.P.4
  • 12
    • 0019859111 scopus 로고
    • Hypotaurine transport in brain slices: Comparison with taurine and GABA
    • Kontro P, Oja SS (1981) Hypotaurine transport in brain slices: comparison with taurine and GABA. Neurochem Res 6:1179-1191
    • (1981) Neurochem Res , vol.6 , pp. 1179-1191
    • Kontro, P.1    Oja, S.S.2
  • 13
    • 0021015938 scopus 로고
    • Mutual interaction in the transport of taurine, hypotaurine and GABA in brain slices
    • Kontro P, Oja SS (1983) Mutual interaction in the transport of taurine, hypotaurine and GABA in brain slices. Neurochem Res 8:1377-1387
    • (1983) Neurochem Res , vol.8 , pp. 1377-1387
    • Kontro, P.1    Oja, S.S.2
  • 15
    • 24444436724 scopus 로고
    • High performance liquid chromatographic determination of sub-picomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehyde
    • Lindroth P, Mopper K (1979) High performance liquid chromatographic determination of sub-picomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehyde. Anal Chem 51:1667-1674
    • (1979) Anal Chem , vol.51 , pp. 1667-1674
    • Lindroth, P.1    Mopper, K.2
  • 16
    • 0028351099 scopus 로고
    • Differential effects of vigabatrin, gamma-acetylenic GABA, aminooxyacetic acid and valproate on levels of various amino acids in rat brain regions and plasma
    • Loscher W, Horstermann D (1994) Differential effects of vigabatrin, gamma-acetylenic GABA, aminooxyacetic acid and valproate on levels of various amino acids in rat brain regions and plasma. Naunyn Schmiedebergs Arch Pharmacol 349:270-278
    • (1994) Naunyn Schmiedebergs Arch Pharmacol , vol.349 , pp. 270-278
    • Loscher, W.1    Horstermann, D.2
  • 17
    • 0031606806 scopus 로고    scopus 로고
    • Novel methods for studying new antiepileptic drug pharmacology
    • French J, Leppik I, Dichter MA (eds). Lippincott-Raven, Philadelphia
    • Mattson RH, Scheyer RD, Petroff OAC, During MJ, Collins TL, Spencer D (1998) Novel methods for studying new antiepileptic drug pharmacology. In: French J, Leppik I, Dichter MA (eds) Advances in neurology, vol 76. Lippincott-Raven, Philadelphia, pp 105-112
    • (1998) Advances in Neurology, Vol 76 , vol.76 , pp. 105-112
    • Mattson, R.H.1    Scheyer, R.D.2    Petroff, O.A.C.3    During, M.J.4    Collins, T.L.5    Spencer, D.6
  • 18
    • 0018749055 scopus 로고
    • Inhibitors of GABA metabolism
    • Metcalf BW (1979) Inhibitors of GABA metabolism. Biochem Pharmacol 28:1705-1712
    • (1979) Biochem Pharmacol , vol.28 , pp. 1705-1712
    • Metcalf, B.W.1
  • 19
    • 4243828370 scopus 로고
    • Intérêt potentiel des agonistes des récepteurs GABA comme antiépileptiques. Etude de leurs spectres d'activité neuropharmacologique
    • Morel E, Bougard M, Worms P, Lourdelet J, Lloyd KG (1983) Intérêt potentiel des agonistes des récepteurs GABA comme antiépileptiques. Etude de leurs spectres d'activité neuropharmacologique. Acta Pharm Biol Clin 2:121-123
    • (1983) Acta Pharm Biol Clin , vol.2 , pp. 121-123
    • Morel, E.1    Bougard, M.2    Worms, P.3    Lourdelet, J.4    Lloyd, K.G.5
  • 21
    • 0023926944 scopus 로고
    • Regulation of transmitter γ-aminobutyric acid (GABA) synthesis and metabolism illustrated by the effect of γ-vinyl GABA and hypoglycemia
    • Paulsen RE, Fonnum F (1988) Regulation of transmitter γ-aminobutyric acid (GABA) synthesis and metabolism illustrated by the effect of γ-vinyl GABA and hypoglycemia. J Neurochem 50:1151-1157
    • (1988) J Neurochem , vol.50 , pp. 1151-1157
    • Paulsen, R.E.1    Fonnum, F.2
  • 24
    • 0018366075 scopus 로고
    • Inhibitory, GABAergic nerve terminals decrease at sites of focal epilepsy
    • Ribak CE, Harris AB, Vaughn JE, Roberts E (1979) Inhibitory, GABAergic nerve terminals decrease at sites of focal epilepsy. Science 205:211-214
    • (1979) Science , vol.205 , pp. 211-214
    • Ribak, C.E.1    Harris, A.B.2    Vaughn, J.E.3    Roberts, E.4
  • 25
    • 0014271426 scopus 로고
    • Biochemical-physiological correlations in studies of the γ-aminobutyric acid system
    • Roberts E, Kuriyama K (1968) Biochemical-physiological correlations in studies of the γ-aminobutyric acid system. Brain Res 8:1-35
    • (1968) Brain Res , vol.8 , pp. 1-35
    • Roberts, E.1    Kuriyama, K.2
  • 26
    • 0025963645 scopus 로고
    • Synthesis and anticonvulsant activity of 1-acyl-2-pyrrolidinone derivatives
    • Sasaki H, Mori Y, Nakamura J, Shibasaki J (1991) Synthesis and anticonvulsant activity of 1-acyl-2-pyrrolidinone derivatives. J Med Chem 34:628-633
    • (1991) J Med Chem , vol.34 , pp. 628-633
    • Sasaki, H.1    Mori, Y.2    Nakamura, J.3    Shibasaki, J.4
  • 27
    • 0023263322 scopus 로고
    • GABA and dopamine interaction in the basal ganglia: Dopaminergic supersensitivity following chronic elevation of brain gamma-aminobutyric acid levels
    • Sivam SP, Hudson PM, Tilson HA, Hong JS (1987) GABA and dopamine interaction in the basal ganglia: dopaminergic supersensitivity following chronic elevation of brain gamma-aminobutyric acid levels. Brain Res 412:29-35
    • (1987) Brain Res , vol.412 , pp. 29-35
    • Sivam, S.P.1    Hudson, P.M.2    Tilson, H.A.3    Hong, J.S.4
  • 28
    • 0030955224 scopus 로고    scopus 로고
    • Brain microdialysis of GABA and glutamate: What does it signify?
    • Timmerman W, Westerink BHC (1997) Brain microdialysis of GABA and glutamate: what does it signify? Synapse 27:242-261
    • (1997) Synapse , vol.27 , pp. 242-261
    • Timmerman, W.1    Westerink, B.H.C.2
  • 29
    • 0023264397 scopus 로고
    • Changes in extracellular amino acids during soman and kainic acid-induced seizures
    • Wade JV, Samson FE, Nelson SR, Pazdernik TL (1987) Changes in extracellular amino acids during soman and kainic acid-induced seizures. J Neurochem 49:645-650
    • (1987) J Neurochem , vol.49 , pp. 645-650
    • Wade, J.V.1    Samson, F.E.2    Nelson, S.R.3    Pazdernik, T.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.