Myoclonic status epilepticus following high-dosage lamotrigine therapy

Brain and Development

Volumn 21, Issue 6, 1999, Pages 420-424

  Guerrini, Renzo ^a   Belmonte, Anna ^a   Parmeggiani, Lucio ^a   Perucca, Emilio ^b  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

Author keywords

Lamotrigine; Myoclonic status epilepticus; Seizure exacerbation

Indexed keywords

CLOBAZAM; LAMOTRIGINE; VIGABATRIN;

ARTICLE; CASE REPORT; ELECTROENCEPHALOGRAM; EPILEPTIC STATE; FEMALE; HUMAN; LENNOX GASTAUT SYNDROME; MYOCLONUS; SCHOOL CHILD;

ANTICONVULSANTS; CHILD; ELECTROENCEPHALOGRAPHY; EPILEPSIES, MYOCLONIC; EPILEPSY, ABSENCE; FEMALE; HUMANS; STATUS EPILEPTICUS; SYNDROME; TRIAZINES;

EID: 0032773205     PISSN: 03877604     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0387-7604(99)00048-0     Document Type: Article

References (21)

1. Goa K.L., Ross S.R., Chrisp P. Lamotrigine. A review of its pharmacological properties and clinical efficacy in epilepsy. Drugs. 46:1993;152-176.
2. Schlumberger E., Chavez F., Palacios L., Rey E., Pajot N., Dulac O. Lamotrigine in treatment of 120 children with epilepsy. Epilepsia. 35:1994;359-367.
3. Mullens L., Gallagher J., Manasco P. The lamictal Lennox-Gastaut study group. Improved neurological function accompanies effective control of the Lennox- Gastaut syndrome with Lamictal: Results of a multinational placebo-controlled trial (abstract). Epilepsia. 37:(Suppl 5):1996;163.
4. Tassinari C.A., Dravet C., Roger J., Cano C., Gastaut H. Tonic status epilepticus precipitated by intravenous benzodiazepine in five patients with Lennox-Gastaut syndrome. Epilepsia. 13:1972;421-435.
5. Lerman P. Seizures induced or aggravated by anticonvulsants. Epilepsia. 39:(Suppl 3):1998;S2-S10.
6. Motte J., Trevathan E., Arvidsson J.F.V., Barrera M.N., Mullens E.L., Manasco P., et al. Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. N Engl J Med. 337:1997;1807-1812.
7. Guerrini R., Belmonte A., Genton P. Antiepileptic drug-induced worsening of seizures in children. Epilepsia. 39:(Suppl 3):1998;S2-S10.
8. Snead O.C., Hosey L.C. Exacerbation of seizures in children by carbamazepine. N Engl J Med. 313:1985;916-921.
9. Talwar D., Arora M.S., Sher P.K. EEG changes and seizure exacerbation in young children treated with carbamazepine. Epilepsia. 35:1994;1154-1159.
10. Troupin A.S., Ojemann L. Paradoxical intoxication - a complication of anticonvulsant administration. Epilepsia. 16:1975;753-758.
11. Stilman N., Masdeu J.C. Incidence of seizures with phenytoin toxicity. Neurology. 35:1985;1769-1772.
12. Lortie A., Chiron C., Mumford J., Dulac O. The potential for increasing seizure frequency, relapse, and appearance of new seizure types with vigabatrin. Neurology. 43:(Suppl 5):1993;S24-S27.
13. Alvarez N., Hartford E., Doubt C. Epileptic seizures induced by clonazepam. Clin Electroenceph. 12:1981;57-65.
14. Ahnut H., Ashman P., Feuerstein T.J., Sauermann W., Saunders M., Schmidt B., et al. Gabapentin (Neurontin) as add-on therapy in patients with partial seizures: a double-blind, placebo-controlled study. Epilepsia. 35:1994;795-801.
15. Besag F.M.C., Wallace S.J., Dulac O., Alving J., Spencer S.C., Hosking G. Lamotrigine for the treatment of epilepsy in childhood. J Pediatr. 127:1995;991-997.
16. Sander J.W.A.S., Patsalos P.N., Oxley J.R., Hamilton M.J., Yuen W.C. A randomized double- blind placebo controlled add-on trial of lamotrigine in patients with severe epilepsy. Epilepsy Res. 6:1990;221-226.
17. Guerrini R., Dravet C., Genton P., Belmonte A., Kaminska A., Dulac O. Lamotrigine and seizure aggravation in severe myoclonic epilepsy. Epilepsia. 39:1998;508-512.
18. Briassoulis G., Kalabalikis P., Tamiolaki M., Hatzis T. Lamotrigine childhood overdose. Pediatr Neurol. 19:1998;239-242.
19. Messenheimer J.A. Lamotrigine. Epilepsia. 36:(Suppl 2):1995;S87-S94.
20. Osorio I., Burnstine T.H., Remler B., Manon-Espaillat R., Reed R.C. Phenytoin- induced seizures: a paradoxical effect at toxic concentrations in epileptic patients. Epilepsia. 30:1989;230-234.
21. So E.L., Ruggles K.H., Cascino G.D., Ahmann P.A., Weatherford K.W. Seizure exacerbation and status epilepticus related to carbamazepine-10,11-epoxide. Ann Neurol. 35:1994;743-746.