Fungemia during murine cryptococcosis sheds some light on pathophysiology

Medical Mycology

Volumn 37, Issue 3, 1999, Pages 169-174

  Lortholary, O ^a   Improvisi, L ^a   Nicolas, M ^a   Provost, F ^a   Dupont, B ^a   Dromer, Françoise ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Cryptococcosis; Experimental model; Fungemia; Mice

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CULTURE; BRAIN; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DISEASE COURSE; DISEASE PREDISPOSITION; FUNGEMIA; INOCULATION; LUNG; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; SPLEEN; TISSUE DISTRIBUTION;

ANIMALS; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; FUNGEMIA; MALE; MICE;

ANIMALIA; FILOBASIDIELLA NEOFORMANS; FUNGI; MURINAE;

EID: 0032772673     PISSN: 13693786     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-280X.1999.00215.x     Document Type: Article

References (25)

1. Mitchell TG, Perfect JR. Cryptococcosis in the era of AIDS -100 years after the discovery of Cryptococcus neoformans. Clin Microbiol Rev 1995; 8: 515-548.
2. Lewis JL, Rabinovich S. The wide spectrum of cryptococcal infections. Am J Med 1972; 53: 315-322.
3. Dismukes WE, Cloud G, Gallis HA, et al. Treatment of cryptococcal meningitis with combination amphotericin B and flucytosine for four as compared with six weeks. New Engl J Med 1987; 317: 334-341.
4. Chuck SL, Sande MA. Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome. New Engl J Med 1989; 321: 794-799.
5. Larsen RA, Leal MAE, Chan LS. Fluconazole compared with amphotericin B plus flucytosine for cryptococcal meningitis in AIDS. Ann Intern Med 1990; 113: 183-187.
6. Rozenbaum R, Rios Gonçalves AJ. Clinical epidemiology study of 171 cases of cryptococcosis. Clin Infect Dis 1994; 18: 369-380.
7. Saag MS, Powderly WG, Cloud GA, et al. Comparison of amphotericin B with fluconazole in the treatment of acute AIDS-associated cryptococcal meningitis. New Engl J Med 1992; 326: 83-89.
8. Clark RA, Greer D, Atkinson W, Valainis GT, Hyslop N. Spectrum of Cryptococcus neoformans infection in 68 patients infected with human immunodeficiency virus. Rev Infect Dis 1990; 12: 768-777.
9. Chechani V, Kamholz SL. Pulmonary manifestations of disseminated cryptococcosis in patients with AIDS. Chest 1990; 98: 1060-1066.
10. Diamond RD. Cryptococcus neoformans. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas and Bennett's. Principles and Practice of Infectious Diseases. New York: Churchill Livingstone, 1995; 2331-2340.
11. Kwon-Chung KJ, Bennett JE. Cryptococcosis. In: Kwon-Chung KJ, Bennett JE, eds. Medical Mycology. Philadelphia: Lea and Febiger, 1992; 397-446.
12. Clemons KV, Brummer E, Stevens DA. Cytokine treatment of central nervous system infection: efficacy of interleukin-12 alone and synergy with conventional antifungal therapy in experimental cryptococcosis. Antimicrob Agents Chemother 1994; 38: 460-464.
13. Hong Nguyen M, Najvar LK, Yu CY, Graybill JR. Combination therapy with fluconazole and flucytosine in the murine model of cryptococcal meningitis. Antimicrob Agents Chemother 1997; 41: 1120-1123.
14. Mukherjee J, Zuckier LS, Scharff MD, Casadevall A. Therapeutic efficacy of monoclonal antibodies to Cryptococcus neoformans glucuronoxylomannan alone and in combination with amphotericin B. Antimicrob Agents Chemother 1994; 38: 580-587.
15. Palou de Fernandez E, Mercedes Patino M, Graybill JR, Tarbit MH. Treatment of cryptococcal meningitis in mice with fluconazole. J Antimicrob Chemother 1986; 18: 261-270.
16. Troke PF, Andrews RJ, Marriott MS, Richardson K. Efficacy of fluconazole (UK-49,858) against experimental aspergillosis and cryptococcosis in mice. J Antimicrob Chemother 1987; 19: 663-670.
17. Velez JD, Allendoerfer R, Luther M, Rinaldi MG, Graybill JR. Correlation of in vitro azole susceptibility with in vivo response in a murine model of cryptococcal meningitis. J Infect Dis 1993; 168: 508-510.
18. Dromer F, Charreire J. Improved amphotericin B (AMB) activity by a monoclonal anti-Cryptococcus neoformans antibody. J Infect Dis 1991; 163: 1114-1120.
19. Macher AM, Bennett JE, Gadek JE, Frank MM. Complement depletion in cryptococcal sepsis. J Immunol 1978; 120: 1686-1690.
20. Graybill JR, Sobel J, Saag M, et al. Cerebrospinal fluid hypertension in patients with AIDS and cryptococcal meningitis. In: Program and Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto. Washington, DC: American Society for Microbiology (1-153), 1997.
21. Bille J, Stockman L, Roberts GD, Horstmeier CD, Ilstrup DM. Evaluation of a lysis-centrifugation system for recovery of yeasts and filamentous fungi from blood. J Clin Microbiol 1983; 18: 469-471.
22. Wheat J. Endemic mycoses in AIDS: a clinical review. Clin Microbiol Rev 1995; 8: 146-159.
23. Yagupsky P, Menegus MA. Cumulative positivity rates of multiple blood cultures for Mycobacterium avium-intracellulare and Cryptococcus neoformans in patients with the acquired immunodeficiency syndrome. Arch Pathol Lab Med 1990; 114: 923-925.
24. Van der Horst CM, Saag MS, Cloud GA, et al. Treatment of cryptococcal meningitis associated with the acquired immune deficiency syndrome. New Engl J Med 1997; 337: 15-21.
25. Kovacs JA, Kovacs AA, Polis M, et al. Cryptococcosis in the acquired immunodeficiency syndrome. Ann Intern Med 1985; 103: 533-538.