Anti-p53 antibodies are rarely detected in serum of patients with rheumatoid arthritis and Sjogren's syndrome

Journal of Rheumatology

Volumn 26, Issue 8, 1999, Pages 1672-1675

  Mariette, Xavier ^a   Sibilia, Jean ^b   Delaforge, Christine ^b   Bengoufa, Djaouida ^b   Brouet, Jean Claude ^b   Soussi, Thierry ^b  

^a SAINT LOUIS HOSPITAL   (France)

^b NONE

Author keywords

Anti p53 antibodies; Lymphoma; p53 mutations; Rheumatoid arthritis; Sjogren's syndrome

Indexed keywords

MUTANT PROTEIN; PROTEIN ANTIBODY; PROTEIN P53;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; AUTOIMMUNE DISEASE; COMORBIDITY; CONTROLLED STUDY; FEMALE; HUMAN; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SJOEGREN SYNDROME; SYNOVIAL FLUID;

ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; SEROLOGIC TESTS; SJOGREN'S SYNDROME; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0032770624     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hollstein M, Sidransky D, Vogelstein B, Harris CC. p53 mutations in human cancers. Science 1991;253:49-53.
2. Soussi T, Legros Y, Lubin R, Ory K, Schlichtholz B. Multifactorial analysis of p53 alteration in human cancer - a review. Int J Cancer 1994;57:1-9.
3. Angelopoulou K, Diamandis EP, Sutherland DJA, Kellen JA, Bunting PS. Prevalence of serum antibodies against the p53 tumor suppressor gene protein in various cancers. Int J Cancer 1994;58:480-7.
4. Winter SF, Sekido Y, Minna JD, et al. Antibodies against autologous tumor cell proteins in patients with small-cell lung cancer. Association with improved survival. J Natl Cancer Inst 1993;85:2012-8.
5. Lubin R, Schlichtholz B, Teillaud JL, et al. p53 antibodies in patients with various types of cancer: assay, identification and characterization. Clin Cancer Res 1995;1:1463-9.
6. Soussi T. The humoral response to the tumor-suppressor gene product p53 in human cancer: implications for diagnosis and therapy. Immunol Today 1996;17:354-6.
7. Firestein GS, Nguyen K, Aupperle KR, Yeo M, Boyle DL, Zvaifler NJ. Apoptosis in rheumatoid arthritis. p53 overexpression in rheumatoid arthritis synovium. Am J Pathol 1996;149:2143-51.
8. Firestein GS, Echeverri F, Yeo M, Zvaifler NJ, Green DR. Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium. Proc Natl Acad Sci USA 1997;94:10895-900.
9. Reme T, Travaglio A, Gueydon E, Adla L, Jorgensen C, Sany J. Mutations of the p53 tumor suppressor gene in erosive rheumatoid synovial tissue. Clin Exp Immunol 1998;111:353-8.
10. Kovacs B, Patel A, Hershey JN, et al. Antibodies against p53 in sera from patients with systemic lupus erythematosus and other rheumatic diseases. Arthritis Rheum 1997;40:980-5.
11. Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
12. Fox RI, Robinson CA, Curd JG, Kozin F, Howell FV. Sjögren's syndrome. Proposed criteria for classification. Arthritis Rheum 1986;29:577-85.
13. Royer B, Cazals-Hatem D, Sibilia J, et al. Lymphomas in patients with Sjögren's syndrome are marginal zone B-cell neoplasma, arise in diverse extranodal and nodal sites, and are not associated with viruses. Blood 1997;90:766-75.
14. Mountz J, Wu J, Cheng J, Zhou T. Autoimmune disease: a problem of defective apoptosis. Arthritis Rheum 1994;37:1415-20.
15. Fisher GH, Rosenberg FJ, Strauss SE, et al. Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 1995;81:935-46.
16. Imamura F, Aono H, Hasunuma T, et al. Monoclonal expansion of synoviocytes in rheumatoid arthritis. Arthritis Rheum 1998;41:1979-86.
17. Preudhome C, Vanrumbeke M, Detourmignies L, et al. Very low incidence of p53 antibodies in adult non-Hodgkin's lymphoma and multiple myeloma. Br J Haematol 1998;100:184-6.