A novel molecular modelling study of inhibitors of the 17α-hydroxylase component of the enzyme system 17α-hydroxylase/17,20-lyase (P-450(17α))

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 8, 1999, Pages 1487-1496

  Ahmed, Sabbir ^a  

^a KINGSTON UNIVERSITY   (United Kingdom)

Author keywords

17 Hydroxylase; Inhibitors; P 450; P 45017 ; Substrate heme complex

Indexed keywords

ANTINEOPLASTIC AGENT; BIFONAZOLE; CYTOCHROME P450; ECONAZOLE; HEME; IMIDAZOLE DERIVATIVE; KETOCONAZOLE; METRONIDAZOLE; MICONAZOLE; OXYGENASE; OXYGENASE INHIBITOR;

ARTICLE; ENZYME ACTIVE SITE; ENZYME INHIBITION; HYDROGEN BOND; HYDROXYLATION; MOLECULAR MODEL;

ENZYME INHIBITORS; HEME; MODELS, MOLECULAR; STEROID 17-ALPHA-HYDROXYLASE;

EID: 0032769656     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00077-2     Document Type: Article

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