Intranasal administration of synthetic recombinant peptide-based vaccine protects mice from infection by Schistosoma mansoni

Infection and Immunity

Volumn 67, Issue 9, 1999, Pages 4360-4366

  Ben Yedidia, T ^a   Tarrab Hazdai, R ^a   Schechtman, D ^a   Arnon, R ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

FLAGELLIN; RECOMBINANT VACCINE; SCHISTOSOMA VACCINE; SYNTHETIC PEPTIDE;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMORAL IMMUNITY; INTRANASAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PARASITE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RECOMBINANT DNA TECHNOLOGY; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; SUBCUTANEOUS DRUG ADMINISTRATION; VACCINATION;

EID: 0032768135     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.9.4360-4366.1999     Document Type: Article

References (39)

1. Anderson, S., V. L. Shires, R. A. Wilson, and A. P. Mountford. 1998. In the absence of IL-2, the induction of Th1-mediated protective immunity by the attenuated schistosome vaccine is impaired, revealing an alternative pathway with Th2-type characteristics. Eur. 3. Immunol. 28:2827-2838.
2. Arnon, A., and R. Levi. 1995. Synthetic recombinant vaccines against viral agents. Int. Arch. Allergy Immunol. 108:321-326.
3. Auriault, C., M. H. Gras, R. J. Pierce, A. E. Butterworth, I. Wolowczuk, M. Capron, J. H. Ouma, J. M. Balloul, J. Khalife, J. L. Neyrinck, et al. 1990. Antibody response of Schistosoma mansoni-infected human subjects to the recombinant P28 glutathione-S-transferase and to synthetic peptides. J. Clin. Microbiol. 28:1918-1924.
4. Ben-Yedidia, T., and R. Arnon. 1997. Design of peptide and polypeptide vaccines. Current Opin. Biotechnol. 8:442-448.
5. Ben-Yedidia, T., and R. Arnon. 1998. Effect of pre-existing carrier immunity on the efficacy of synthetic influenza vaccine. Immunol. Lett. 64:9-15.
6. Bergquist, N. R. 1995. Controlling schistosomiasis by vaccination: a realistic opinion? Parasitol. Today. 11:191-194.
7. Capron, A., J. P. Dessaint, M. Capron, and R. J. Pierce. 1991 Vaccine strategies against schistosomiasis. Mem. Inst. Oswaldo Cruz 4:19-27.
8. Capron, A., G. Riveau, J. M. Grzych, D. Boulanger, M. Capron, and R. Pierce. 1994. Development of a vaccine strategy against human and bovine schistosomiasis. Background and update. Trop. Geogr. Med. 46:242-246.
9. Harn, D. A., W. Gu, L. D. Oligino, M. Mitsuyama, A. Gebremichael, and D. Richter. 1992. A protective monoclonal antibody specifically recognizes and alters the catalytic activity of schistosome triose-phosphate isomerase. J. Immunol. 148:562-567.
10. Hunter, W. M., and F. C. Greenwood. 1962. Preparation of iodine 131 labeled growth hormone of high specific activity. Nature 194:595-596.
11. Ibrahim, G. F., G. H. Fleet, M. L. Lyons, and R. A. Walter. 1985. Method for the isolation of highly purified Salmonella flagellin. J. Clin. Microbiol. 22: 1040-1044.
12. Kremer, L., G. Riveau, A. Baulard, A. Capron, and C. Locht. 1996. Neutralizing antibody responses elicited in mice immunized with recombinant bacillus Calmette-Guerin producing the Schistosoma mansoni glutathione S-transferase. J. Immunol. 156:4309-4317.
13. Levi, R., and R. Arnon. 1996. Synthetic recombinant influenza vaccine induces efficient long-term immunity and cross-strain protection. Vaccine 14: 85-92.
14. Levi-Schaffer, F., M. D. Schryer, and M. Smolarsky. 1982. The resistance of schistosomula of Schistosoma mansoni to antibodies and complement invitro does not correlate with the binding of antibodies to the surface of the parasite. J. Immunol. 129:2744-2751.
15. McEwen, J., R. Levi, R. J. Horwitz, and R. Arnon. 1992. Synthetic recombinant vaccine expressing influenza haemagglutinin epitope in Salmonella flagellin leads to partial protection in mice. Vaccine 10:405-411.
16. Mendlovic, F., R. Arnon, R. Tarrab-Hazdai, and J. Puri. 1989. Genetic control of immune response to a purified Schistosoma mansoni antigen. II. Establishment and characterization of specific I-A and I-E restricted T-cell clones. Parasite Immunol. 11:683-694.
17. Muller, S., N. Benkirane, G. Guichard, M. Van Regenmortel, and F. Brown. 1998. The potential of retro-inverso peptides as synthetic vaccines. Exp. Opin. Invest. Drugs 7:1429-1438.
18. Newton, S. M., T. M. Joys, S. A. Anderson, R. C. Kennedy, M. E. Hovi, and B. A. Stocker. 1995. Expression and immunogenicity of an 18-residue epitope of HIV1 gp41 inserted in the flagellar protein of a Salmonella live vaccine. Res. Microbiol. 146:203-216.
19. Newton, S. M., M. Kotb, T. P. Poirier, B. A. Stocker, and E. H. Beachey. 1991. Expression and immunogenicity of a streptococcal M protein epitope inserted in Salmonella flagellin. Infect. Immun. 59:2158-2165.
20. Newton, S. M., C. O. Jacob, and B. A. Stocker. 1989. Immune response to cholera toxin epitope inserted in Salmonella flagellin expression and livevaccine potential. Science 244:70-72.
21. Pancre, V., H. Gras-Masse, A. Delanoye, J. Herno, A. Capron, and C. Auriault. 1996. Induction of cytotoxic T-cell activity by the protective antigen of Schistosoma mansoni Sm28GST or its derived C-terminal lipopeptide. Scand. J. Immunol. 44:485-492.
22. Pearce, E. J., S. L. James, S. Hieny, D. E. Lanar, and A. Sher. 1988. Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen. Proc. Natl. Acad. Sci. USA 85:5678-5682.
23. Reynolds, S. R., C. E. Dahl, and D. A. Ham. 1994. T and B epitope determination and analysis of multiple antigenic peptides for Schistosoma mansoni experimental vaccine triose-phosphate isomerase. J. Immunol. 152:193-200.
24. Reynolds, S. R., C. B. Schoemaker, and D. A. Harn. 1992. T and B cell epitope mapping of SM 23, an integral membrane protein of Schistosoma mansoni. J. Immunol. 149:3995-4001.
25. Richter, D., R. N. Incani, and D. A. Harn. 1993. Isotype responses to candidate vaccine antigens in protective sera obtained from mice vaccinated with irradiated cercariae of Schistosoma mansoni. Infect. Immun. 61:3003-3011.
26. Smithers, S. R. and R. J. Terry. 1965. The infection of laboratory hosts with cercariae of S. mansoni and the recovery of adults worms. Parasitology 55:695-700.
27. Soisson, L. A., G. D. R. Reid, I. O. Farah, M. Nyindo, and M. Strand. 1993. Protective immunity in baboons vaccinated with a recombinant antigen or radiation-attenuated cercariae of Schistosoma mansoni is antibody-dependent. J. Immunol. 151:4782-4789.
28. Soisson, L. M. A., C. P. Masterson, T. D. Tom, M. T. McNally, G. H. Lowell, and M. Strand. 1992. Induction of protective immunity in mice using a 62-kDa recombinant fragment of a Schistosoma mansoni surface antigen. J. Immunol. 149:3612-3620.
29. Staros, J. V., R. W. Wright, and D. M. Swingle. 1986. Enhancement by N-hydroxysulfosuccinimide of water-soluble carbodiimide-mediated coupling reactions. Anal. Biochem. 156:220-222.
30. Stocker, B. A. 1990. Aromatic-dependent Salmonella as live vaccine presenters of foreign epitopes as inserts in flagellin. Res. Microbiol. 141:787-796.
31. Stocker, B. A. and S. M. Newton. 1994. Immune responses to epitopes inserted in Salmonella flagellin. Int. Rev. Immunol. 11:167-178.
32. Tarrab-Hazdai, R., F. Levi-schaffer, V. Brenner, S. Horowitz, Z. Eshhar, and R Arnon. 1985. Protective monoclonal antibodies against Schistosoma mansoni. Antigen isolation, characterization and suitability for active immunization. J. Immunol. 135:2772-2779.
33. Tarrab-Hazdai, R., D. Schechtman, and R. Arnon. 1998. Synthesis and characterization of a protective peptide-based vaccine against Schistosoma mansoni. Infect. Immun. 66:4526-4530.
34. Tarrab-Hazdai, R., D. Schechtman, G. Lowell, E. Pirak, and R. Arnon. 1999. Proteosome delivery of a protective 9B-antigen against Schistosoma mansoni. Int. J. Immunopharmacol. 21:205-218.
35. Tendler, M., C. A. Brito, M. M. Vilar, N. Serra-Freire, C. M. Diogo, M. S. Almeida, A. C. B. Delbem, J. F. DA Silva, W. Savino, R. C. Garratt, et al. 1996. A Schistosoma mansoni fatty acid-binding protein, Sm14, is the potential basis of a dual-purpose anti-helminth vaccine. Proc. Natl. Acad. Sci. USA 93:269-273.
36. Towbin, H., T. Stahelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
37. Verma, N. K., H. K. Ziegler, B. A. Stocker, and G. K. Schoolnik. 1995. Induction of a cellular immune response to a defined T-cell epitope as an insert in the flagellin of a live vaccine strain of Salmonella. Vaccine 13:235-244.
38. Warren, K. S., E. Q. Domingo, and R. T. Cowan. 1967. Granuloma formation around schistosome eggs as a manifestation of delayed hypersensitivity. Am. J. Pathol. 51:735-756.
39. Yang, W., G. N. Gobert, and D. P. McManus. 1997. Oral vaccination of mice with recombinant Schistosoma japonicum proteins induces specific anti-parasite antibodies and damage to adult worms after a challenge infection. Int. J. Parasitol. 27:843-853.