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Volumn 154, Issue 1-2, 1999, Pages 101-109

Opposite regulation of PPAR-α and -γ gene expression by both their ligands and retinoic acid in brown adipocytes

Author keywords

15 deoxy 12,14 prostaglandin J2; Brown adipocyte; Peroxisome proliferator activated receptor; PPAR; Retinoic acid; Wy 14,643

Indexed keywords

ALITRETINOIN; CYCLOHEXIMIDE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIRINIXIC ACID; RECEPTOR SUBTYPE; RETINOIC ACID;

EID: 0032767703     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0303-7207(99)00081-7     Document Type: Article
Times cited : (53)

References (47)
  • 1
    • 0028955276 scopus 로고
    • A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene
    • Alvarez R., deAndrés J., Yubero P., Viñas O., Mampel T., Iglesias R., Giralt M., Villarroya F. A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene. J. Biol. Chem. 270:1995;5666-5673.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5666-5673
    • Alvarez, R.1    Deandrés, J.2    Yubero, P.3    Viñas, O.4    Mampel, T.5    Iglesias, R.6    Giralt, M.7    Villarroya, F.8
  • 2
    • 0013486707 scopus 로고    scopus 로고
    • Understanding the intracellular pathways for the retinoic acid induction of brown fat ucp gene: Ligands, receptors and gene elements
    • C.S. Thibeault. Southborough: IBC Library Series
    • Alvarez R., Brun S., Viñas O., Mampel T., Iglesias R., Giralt M., Villarroya F. Understanding the intracellular pathways for the retinoic acid induction of brown fat ucp gene: ligands, receptors and gene elements. Thibeault C.S. Obesity II. Recent advances in understanding and treatment. 1997;307-318 IBC Library Series, Southborough.
    • (1997) Obesity II. Recent Advances in Understanding and Treatment , pp. 307-318
    • Alvarez, R.1    Brun, S.2    Viñas, O.3    Mampel, T.4    Iglesias, R.5    Giralt, M.6    Villarroya, F.7
  • 3
    • 0028909362 scopus 로고
    • Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors
    • Amri E.Z., Bonino F., Ailhaud G., Abumrad N.A., Grimaldi P.A. Cloning of a protein that mediates transcriptional effects of fatty acids in preadipocytes. Homology to peroxisome proliferator-activated receptors. J. Biol. Chem. 270:1995;2367-2371.
    • (1995) J. Biol. Chem. , vol.270 , pp. 2367-2371
    • Amri, E.Z.1    Bonino, F.2    Ailhaud, G.3    Abumrad, N.A.4    Grimaldi, P.A.5
  • 4
    • 0031017481 scopus 로고    scopus 로고
    • Identification of a retinoid/chicken ovalbumin upstream promoter transcription factor response element in the human retinoid X receptor γ2 gene promoter
    • Barger P.M., Kelly D.P. Identification of a retinoid/chicken ovalbumin upstream promoter transcription factor response element in the human retinoid X receptor γ2 gene promoter. J. Biol. Chem. 272:1997;2722-2728.
    • (1997) J. Biol. Chem. , vol.272 , pp. 2722-2728
    • Barger, P.M.1    Kelly, D.P.2
  • 5
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-α, -β, and -γ In the adult rat
    • Braissant O., Foufelle F., Scotto C., Dauca M., Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, and -γ in the adult rat. Endocrinology. 137:1996;354-366.
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 6
    • 0031788318 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptor-α, -β, and -γ During rat embryonic development
    • Braissant O., Wahli W. Differential expression of peroxisome proliferator-activated receptor-α, -β, and -γ during rat embryonic development. Endocrinology. 139:1998;2748-2754.
    • (1998) Endocrinology , vol.139 , pp. 2748-2754
    • Braissant, O.1    Wahli, W.2
  • 7
    • 0342334561 scopus 로고
    • Molecular approach to thermogenesis in brown adipose tissue: CDNA cloning of the mitochondrial uncoupling protein
    • Bouillaud F., Ricquier D., Thibault J., Weissenbach J. Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein. Proc. Natl. Acad. Sci. USA. 82:1985;445-448.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 445-448
    • Bouillaud, F.1    Ricquier, D.2    Thibault, J.3    Weissenbach, J.4
  • 9
    • 0027237512 scopus 로고
    • Induction of Rev-Erb α, an orphan receptor encoded on the opposite strand of the α-thyroid hormone receptor gene, during adipocyte differentiation
    • Chawla A., Lazar M.A. Induction of Rev-Erb α, an orphan receptor encoded on the opposite strand of the α-thyroid hormone receptor gene, during adipocyte differentiation. J. Biol. Chem. 268:1993;16265-16269.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16265-16269
    • Chawla, A.1    Lazar, M.A.2
  • 11
    • 0026517010 scopus 로고
    • Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors
    • Dreyer C., Krey G., Keller H., Givel F., Helftenbein G., Wahli W. Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell. 68:1992;879-887.
    • (1992) Cell , vol.68 , pp. 879-887
    • Dreyer, C.1    Krey, G.2    Keller, H.3    Givel, F.4    Helftenbein, G.5    Wahli, W.6
  • 12
    • 0032230261 scopus 로고    scopus 로고
    • The short- And long-term effects of tumor necrosis factor-α And BRL 49653 on peroxisome proliferator-activated receptor (PPAR) γ2 gene expression and other adipocyte genes
    • Edelstein-Rosenbaum S., Greenberg A.S. The short- and long-term effects of tumor necrosis factor-α and BRL 49653 on peroxisome proliferator-activated receptor (PPAR) γ2 gene expression and other adipocyte genes. Mol. Endocrinol. 12:1998;1150-1160.
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1150-1160
    • Edelstein-Rosenbaum, S.1    Greenberg, A.S.2
  • 13
    • 0027161296 scopus 로고
    • Reduction of background problems in non-radioactive northern and Southern blot analyses enables higher sensitivity than 32P-based hybridizations
    • Engler-Blum G., Meier M., Frank J., Muller G.A. Reduction of background problems in non-radioactive northern and Southern blot analyses enables higher sensitivity than 32P-based hybridizations. Anal. Biochem. 210:1993;235-244.
    • (1993) Anal. Biochem. , vol.210 , pp. 235-244
    • Engler-Blum, G.1    Meier, M.2    Frank, J.3    Muller, G.A.4
  • 14
    • 0030582447 scopus 로고    scopus 로고
    • Induction of uncoupling protein in brown adipose tissue. Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent
    • Foellmi-Adams L.A., Wyse B.M., Herron D., Nedergaard J., Kletzien R.F. Induction of uncoupling protein in brown adipose tissue. Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent. Biochem. Pharmacol. 52:1996;693-701.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 693-701
    • Foellmi-Adams, L.A.1    Wyse, B.M.2    Herron, D.3    Nedergaard, J.4    Kletzien, R.F.5
  • 15
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
    • Forman B.M., Tontonoz P., Chen J., Brun R.P., Spiegelman B.M., Evans R.M. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ Cell. 83:1995;803-812.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 17
    • 0022633687 scopus 로고
    • Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription
    • Greenberg M.E., Hermanowski A.L., Ziff E.B. Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription. Mol. Cell. Biol. 6:1986;1050-1057.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 1050-1057
    • Greenberg, M.E.1    Hermanowski, A.L.2    Ziff, E.B.3
  • 18
    • 0025021268 scopus 로고
    • Differential and tissue-specific regulation of the multiple rat c-erbA messenger RNA species by thyroid hormone
    • Hodin R.A., Lazar M.A., Chin W.W. Differential and tissue-specific regulation of the multiple rat c-erbA messenger RNA species by thyroid hormone. J. Clin. Invest. 85:1990;101-105.
    • (1990) J. Clin. Invest. , vol.85 , pp. 101-105
    • Hodin, R.A.1    Lazar, M.A.2    Chin, W.W.3
  • 19
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I., Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature. 347:1990;645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 20
    • 0027447461 scopus 로고
    • Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers
    • Keller H., Dreyer C., Medin J., Mahfoudi A., Ozato K., Wahli W. Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers. Proc. Natl. Acad. Sci. USA. 90:1993;2160-2164.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2160-2164
    • Keller, H.1    Dreyer, C.2    Medin, J.3    Mahfoudi, A.4    Ozato, K.5    Wahli, W.6
  • 21
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • Kliewer S.A., Umesono K., Noonan D.J., Heyman R.A., Evans R.M. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature. 358:1992;771-774.
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 24
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ)
    • Lehmann J.M., Moore L.B., Smith Oliver T.A., Wilkison W.O., Willson T.M., Kliewer S.A. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ (PPAR γ). J. Biol. Chem. 270:1995;12953-12956.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 25
    • 0028003839 scopus 로고
    • Regulation of the peroxisome proliferator-activated receptor α gene by glucocorticoids
    • Lemberger T., Staels B., Saladin R., Desvergne B., Auwerx J., Wahli W. Regulation of the peroxisome proliferator-activated receptor α gene by glucocorticoids. J. Biol. Chem. 269:1994;24527-24530.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24527-24530
    • Lemberger, T.1    Staels, B.2    Saladin, R.3    Desvergne, B.4    Auwerx, J.5    Wahli, W.6
  • 26
    • 0029731662 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: A nuclear receptor signaling pathway in lipid physiology
    • Lemberger T., Desvergne B., Wahli W. Peroxisome proliferator-activated receptors: a nuclear receptor signaling pathway in lipid physiology. Ann. Rev. Cell. Dev. Biol. 12:1996a;335-363.
    • (1996) Ann. Rev. Cell. Dev. Biol. , vol.12 , pp. 335-363
    • Lemberger, T.1    Desvergne, B.2    Wahli, W.3
  • 28
    • 0031041075 scopus 로고    scopus 로고
    • Regulating adipogenesis
    • Mandrup S., Lane M.D. Regulating adipogenesis. J. Biol. Chem. 272:1997;5367-5370.
    • (1997) J. Biol. Chem. , vol.272 , pp. 5367-5370
    • Mandrup, S.1    Lane, M.D.2
  • 29
    • 0002742859 scopus 로고
    • The bioenergetic mechanisms of brown adipose tissue mitochondria
    • P. Trayhurn, & D.G. Nicholls. London: Edward Arnold
    • Nicholls D.G., Cunningham S.A., Rial E. The bioenergetic mechanisms of brown adipose tissue mitochondria. Trayhurn P., Nicholls D.G. Brown Adipose Tissue. 1986;52-85 Edward Arnold, London.
    • (1986) Brown Adipose Tissue , pp. 52-85
    • Nicholls, D.G.1    Cunningham, S.A.2    Rial, E.3
  • 30
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P., Wu Z., Park C.W., Graves R., Wright M., Spiegelman B.M. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 92:1998;829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 31
    • 0024997854 scopus 로고
    • α- And β-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture
    • Rehnmark S., Nechad M., Herron D., Cannon B., Nedergaard J. α- and β-adrenergic induction of the expression of the uncoupling protein thermogenin in brown adipocytes differentiated in culture. J. Biol. Chem. 265:1990;16464-16471.
    • (1990) J. Biol. Chem. , vol.265 , pp. 16464-16471
    • Rehnmark, S.1    Nechad, M.2    Herron, D.3    Cannon, B.4    Nedergaard, J.5
  • 33
    • 0029941669 scopus 로고    scopus 로고
    • Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: Regulation by peroxisome proliferator-activated receptor γ
    • Sears I.B., MacGinnitie M.A., Kovacs L.G., Graves R.A. Differentiation-dependent expression of the brown adipocyte uncoupling protein gene: regulation by peroxisome proliferator-activated receptor γ Mol. Cell. Biol. 16:1996;3410-3419.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3410-3419
    • Sears, I.B.1    MacGinnitie, M.A.2    Kovacs, L.G.3    Graves, R.A.4
  • 34
    • 0026785388 scopus 로고
    • Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids
    • Schmidt A., Endo N., Rutledge S.J., Vogel R., Shinar D., Rodan G.A. Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids. Mol. Endocrinol. 6:1992;1634-1641.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 1634-1641
    • Schmidt, A.1    Endo, N.2    Rutledge, S.J.3    Vogel, R.4    Shinar, D.5    Rodan, G.A.6
  • 35
    • 0030602866 scopus 로고    scopus 로고
    • The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation
    • Schoonjans K., Staels B., Auwerx J. The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation. Biochim. Biophys. Acta. 1302:1996;93-109.
    • (1996) Biochim. Biophys. Acta , vol.1302 , pp. 93-109
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 36
    • 0032564864 scopus 로고    scopus 로고
    • Uncoupling: New approaches to an old problem of bioenergetics
    • Skulachev V.P. Uncoupling: new approaches to an old problem of bioenergetics. Biochim. Biophys. Acta. 1363:1998;100-124.
    • (1998) Biochim. Biophys. Acta , vol.1363 , pp. 100-124
    • Skulachev, V.P.1
  • 37
    • 0028327603 scopus 로고
    • Two thyroid response elements are present in the promoter of human thyroid hormone receptor β 1
    • Suzuki S., Miyamoto T., Opsahl A., Sakurai A., DeGroot L.J. Two thyroid response elements are present in the promoter of human thyroid hormone receptor β 1. Mol. Endocrinol. 8:1994;305-314.
    • (1994) Mol. Endocrinol , vol.8 , pp. 305-314
    • Suzuki, S.1    Miyamoto, T.2    Opsahl, A.3    Sakurai, A.4    Degroot, L.J.5
  • 40
    • 0024404265 scopus 로고
    • Differential expression and ligand regulation of the retinoic acid receptor α and β genes
    • de The H., Marchio A., Tiollais P., Dejean A. Differential expression and ligand regulation of the retinoic acid receptor α and β genes. EMBO J. 8:1989;429-433.
    • (1989) EMBO J. , vol.8 , pp. 429-433
    • De The, H.1    Marchio, A.2    Tiollais, P.3    Dejean, A.4
  • 41
    • 0025098239 scopus 로고
    • Identification of a retinoic acid responsive element in the retinoic acid receptor β gene
    • de The H., Vivanco Ruiz M.M., Tiollais P., Stunnenberg H., Dejean A. Identification of a retinoic acid responsive element in the retinoic acid receptor β gene. Nature. 343:1990;177-180.
    • (1990) Nature , vol.343 , pp. 177-180
    • De The, H.1    Vivanco Ruiz, M.M.2    Tiollais, P.3    Stunnenberg, H.4    Dejean, A.5
  • 43
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR γ 2, a lipid-activated transcription factor
    • Tontonoz P., Hu E., Spiegelman B.M. Stimulation of adipogenesis in fibroblasts by PPAR γ 2, a lipid-activated transcription factor. Cell. 79:1994b;1147-1156.
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 44
    • 0032946225 scopus 로고    scopus 로고
    • Retinoids and adipose tissues: Metabolism, cell differentiation and gene expression
    • Villarroya F., Giralt M., Iglesias R. Retinoids and adipose tissues: metabolism, cell differentiation and gene expression. Int. J. Obes. 23:1999;1-6.
    • (1999) Int. J. Obes. , vol.23 , pp. 1-6
    • Villarroya, F.1    Giralt, M.2    Iglesias, R.3
  • 45
    • 0032055908 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis in brown adipose tissue: Nuclear respiratory factor-2/GA-binding protein is responsible for the transcriptional regulation of the gene for the mitochondrial ATP synthase β subunit
    • Villena J.A., Viñas O., Mampel T., Iglesias R., Giralt M., Villarroya F. Regulation of mitochondrial biogenesis in brown adipose tissue: nuclear respiratory factor-2/GA-binding protein is responsible for the transcriptional regulation of the gene for the mitochondrial ATP synthase β subunit. Biochem. J. 331:1998;121-127.
    • (1998) Biochem. J. , vol.331 , pp. 121-127
    • Villena, J.A.1    Viñas, O.2    Mampel, T.3    Iglesias, R.4    Giralt, M.5    Villarroya, F.6
  • 46
    • 0029919647 scopus 로고    scopus 로고
    • Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARγ
    • Xue J.C., Schwartz E.J., Chawla A., Lazar M.A. Distinct stages in adipogenesis revealed by retinoid inhibition of differentiation after induction of PPARγ Mol. Cell. Biol. 16:1996;1567-1575.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1567-1575
    • Xue, J.C.1    Schwartz, E.J.2    Chawla, A.3    Lazar, M.A.4
  • 47
    • 0027749599 scopus 로고
    • Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver
    • Zhu Y., Alvares K., Huang Q., Rao M.S., Reddy J.K. Cloning of a new member of the peroxisome proliferator-activated receptor gene family from mouse liver. J. Biol. Chem. 268:1993;26817-26820.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26817-26820
    • Zhu, Y.1    Alvares, K.2    Huang, Q.3    Rao, M.S.4    Reddy, J.K.5


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