Thermodynamic in vitro studies as a method to investigate the pharmacodynamic behavior of adenosine A1 receptor ligands

Pharmaceutical Research

Volumn 16, Issue 7, 1999, Pages 1054-1058

  Dalpiaz, Alessandro ^a   Scatturin, Angelo ^a   Pavan, Barbara ^c   Varani, Katia ^b   IJzerman, Adriaan P ^c   Borea, Pier Andrea ^b  

^a Dept of Pharmaceutical Sciences ^*  (Italy)

^b Section of Pharmacology   (Italy)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Adenosine A1 receptor; Binding thermodynamics; Full and partial agonists; Intrinsic activity; Pharmacodynamic

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DRUG ACTIVITY; ENTHALPY; ENTROPY; MALE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; TEMPERATURE DEPENDENCE; THERMODYNAMICS;

ADENOSINE; ADIPOCYTES; ANIMALS; BRAIN; CYCLIC AMP; FORSKOLIN; KINETICS; LIGANDS; MALE; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P1; TEMPERATURE; THERMODYNAMICS;

EID: 0032767081     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018987816891     Document Type: Article

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