A facile one-step synthesis of 2,4-adamantanedione

Synthetic Communications

Volumn 29, Issue 18, 1999, Pages 3221-3225

  Bobek, Michael M ^a   Brinker, Udo H ^a  

^a INSTITUT FÜR ORGANISCHE CHEMIE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 ADAMANTANEDIONE; AMANTADINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; GAS CHROMATOGRAPHY; OXIDATION; SYNTHESIS; TEMPERATURE DEPENDENCE;

EID: 0032765658     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919908085947     Document Type: Article

References (19)

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6. In the absence of acetic anhydride yields suffer significantly. Also see Ref. 4 and 9.
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11. >95% starting material recovered.
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13. <12% conversion.
14. Pyridinium-chlorochromate oxidation in the same medium afforded a variety of chlorinated products in addition to 2, 3 and 4.
15. Müller, P.; Blanc, J. Helv. Chim. Acta 1979, 62, 1980.
16. Alternatively, continuous extraction with ether could be performed.
17. Duddeck, H.; Wiskamp, V.; Rosenbaum, D. J. Org. Chem. 1981, 46, 5332.
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19. Yields based on consumed adamantanone. Analytical data in agreement with Ref. 7, 16 and 17.