Increased 'peripheral-type' benzodiazepine receptor sites and mRNA in thalamus of thiamine-deficient rats

Neurochemistry International

Volumn 35, Issue 5, 1999, Pages 363-369

  Desjardins, Paul ^a   Todd, Kathryn G ^a   Hazell, Alan S ^a   Butterworth, Roger F ^a  

^a Neuroscience Research Unit   (Canada)

Author keywords

Astrocytes; Microglia; Neuronal cell death; Peripheral type benzodiazepine receptor; Positron Emission Tomography; Thiamine; Thiamine deficiency

Indexed keywords

BENZODIAZEPINE RECEPTOR; CARBON 11;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DEATH; CONTROLLED STUDY; GLIOSIS; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NERVE CELL; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THALAMUS; THIAMINE DEFICIENCY; WERNICKE ENCEPHALOPATHY;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; GLIAL FIBRILLARY ACIDIC PROTEIN; ISOQUINOLINES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THALAMUS; THIAMINE DEFICIENCY; TRITIUM;

EID: 0032765365     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(99)00082-0     Document Type: Article

References (38)

1. Aikawa H., Watanabe I.S., Furuse T., Iwasaki Y., Satoyoshi E., Sumi T., Moroji T. Low energy levels in thiamine-deficient encephalopathy. J. Neuropathol. Exp. Neurol. 43:1984;276-287.
2. Anholt R.R.H. Mitochondrial benzodiazepine receptors as potential modulators of intermediary metabolism. TIPS. 7:1986;506-511.
3. Basile A.S., Skolnick P. Subcellular localization of "peripheral-type" binding sites for benzodiazepines in rat brain. J. Neurochem. 46:1986;305-308.
4. Benavides J., Fage D., Carter C., Scatton B. Peripheral-type benzodiazepine binding sites are a sensitive index of neuronal damage. Brain Res. 421:1987;167-172.
5. Butterworth R.F. Pathophysiologic mechanisms responsible for the reversible (thiamine responsive) and irreversible (thiamine non-responsive) neurological signs of Wernicke's Encephalopathy. Drug and Alcohol Review. 12:1993;317-324.
6. Butterworth R.F., Héroux M. Effect of pyrithiamine treatment and subsequent thiamine rehabilitation on regional cerebral amino acids and thiamine-dependent enzymes. J. Neurochem. 52:1989;1079-1084.
7. Butterworth R.F., Gaudreau C., Vincelette J., Bourgault A.M., Lamothe F., Nutini A.M. Thiamine deficiency and Wernicke's encephalopathy in AIDS. Metab. Brain Dis. 6:1991;20-212.
8. Caligasan N.Y., Baker H., Sheu K-F.R., Gibson G. Blood-brain barrier abnormalities in vulnerable brain regions during thiamine deficiency. Exp. Neurol. 134:1995;64-72.
9. Charness M.E., DeLaPaz R.J. Mammillary body atrophy in Wernicke's Encephalopathy: antemortem identification using magnetic resonance imaging. Ann. Neurol. 22:1987;595-600.
10. Collins G.H. Glial changes in the brain stem of thiamine-deficient rats. Am. J. Pathol. 50:1967;791-814.
11. D'Iorio D., Welner S.A., Butterworth R.F., Meaney M.J., Suranyi-Cadotte B.E. Peripheral benzodiazepine binding sites in Alzheimer's disease frontal and temporal cortex. Neurobiol. Aging. 12:1991;255-258.
12. Gibson G.E., Ksiezak-Reding H., Sheu K-F.R., Mykytyn V., Blass J.P. Correlation of enzymatic, metabolic, and behavioural deficits in thiamine deficiency and its reversal. Neurochem. Res. 9:1984;803-814.
13. Harper C. Wernicke's encephalopathy: a more common disease than realized. J. Neurol. Neurosurg. Psychiatry. 42:1979;226-231.
14. Harper C.G., Butterworth R.F. Nutritional and metabolic disorders. Graham D.I., Lantos P.L. Greenfield's Neuropathology. 1997;601-655 Arnold, London, UK.
15. Hazell A.S., Butterworth R.F., Hakim A.M. Cerebral vulnerability is associated with selective increase in extracellular glutamate concentration in experimental thiamine deficiency. J. Neurochem. 61:1993;1155-1158.
16. Héroux M., Butterworth R.F. Animal models of the Wernicke-Korsakoff syndrome. Boulton A., Baker G., Butterworth R.F. Neuromethods: Animal Models of Neurologic Disease, II. vol. 22:1992;9-131 Human press, New Jersey.
17. Itzhak Y., Baker L.L., Norenberg. Characterization of the peripheral-type benzodiazepine receptors in cultured astrocytes: evidence for multiplicity. Glia. 9:1993;211-218.
18. Kril J.J., Butterworth R.F. Diencephalic and cerebellar pathology in alcoholic and nonalcoholic patients with end-stage liver disease. Hepatology. 26:1997;837-841.
19. Langlais P.J., Mair R.G. Protective effects of the glutamate antagonist MK-801 on pyrithiamine-induced lesions and amino acid changes in rat brain. J. Neurosci. 10:1990;1664-1674.
20. 3H]PK11195 in vulnerable regions of the rat brain in thiamine deficiency encephalopathy. J. Cereb. Blood Flow and Metab. 14:1994;100-105.
21. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;26-275.
22. Myers R. Mitochondrial benzodiazepine receptor ligands as indicators of damage in the CNS: their application to Positron Emission Tomography. Giesen-Crouse E. Peripheral Benzodiazepine Receptors. 1993;235-267 Academic Press. Chapter 13.
23. Nudel U., Zakut R., Shani M., Neuman S., Levy Z., Yaffe D. The nucleotide sequence of the rat cytoplasmic beta-actin gene. Nucleic Acids Res. 11:1983;1759-1771.
24. 3H-flunitrazepam binding in kainate-lesioned rat striatum and in temporal cortex of brains from patients with senile dementia of the Alzheimer type. Brain Res. 278:1983;373-375.
25. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1982;Academic Press, New York.
26. Robertson D.M., Wasan S.M., Skinner D.B. Ultrastructural features of early brain stem lesions of thiamine-deficient rats. Am. J. Pathol. 52:1968;1081-1087.
27. 3H-Ro5-4864 benzodiazepine binding in the kainate lesioned striatum and Huntington's diseased basal ganglia. Brain Res. 248:1982;396-401.
28. Sprengel R., Werner P., Seeburg P.H., Mukhin A.G., Santi M.R., Grayson D.R., Guidottti A.A., Krueger K.E. Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor. J. Biol. Chem. 264:1989;20415-20421.
29. Syapin P.J., Skolnick P. Characterization of benzodiazepine binding sites in cultured cells of neural origin. J. Neurochem. 32:1979;1047-1051.
30. Tellez I., Terry R.D. Fine structure of the early changes in the vestibular nuclei of the thiamine-deficient rat. Am. J. Pathol. 52:1968;777-794.
31. Todd K.G., Butterworth R.F. Increased neuronal cell survival after L-Deprenyl treatment in experimental thiamine deficiency. J. Neurosci. Res. 52:1998;240-246.
32. Todd K., Butterworth R.F. Evaluation of the role of NMDA-mediated excitotoxicity in the selective neuronal loss in experimental Wernicke encephalopathy. Exp. Neurol. 149:1998;130-138.
33. Todd, K.G., Butterworth, R.F., 1999. Early microglial response in experimental thiamine deficiency: an immunohistochemical analysis. Glia 25, 190-198.
34. Torvik A., Lindboe C.F., Rodge S. Brain lesions in alcoholics: a neuropathological study with clinical correlations. J. Neurol. Sci. 56:1982;233-248.
35. Troncoso J.C., Johnston M.V., Hess K.M., Griffin J.W., Price D.L. Model of Wernicke's encephalopathy. Arch. Neurol. 38:1981;350-354.
36. Victor M., Adams R.D., Collins G.H. The Wernicke-Korsakoff Syndrome and Related Neurologic Disorders due to Alcoholism and Malnutrition. 2nd ed. 1989;F.A. Davies, Philadelphia.
37. Watanabae I., Kanabe S. Early edematous lesion of pyrithiamine induced acute thiamine deficient encephalopathy in the mouse. J. Neuropathol. Exp. Neurol. 36:1978;401-413.
38. Zhang S.X., Weilersbacher G.S., Henderson S.W., Corso T., Olney J.W., Langlais P.J. Excitotoxic cytopathology, progression and reversibility of thiamine deficiency-induced diencephalic lesions. J. Neuropath. Exp. Neurol. 54:1995;255-267.