Omeprazole has a dual mechanism of action: It inhibits both H+K+ATPase and gastric mucosa carbonic anhydrase enzyme in humans (in vitro and in vivo experiments)

Journal of Pharmacology and Experimental Therapeutics

Volumn 290, Issue 2, 1999, Pages 530-534

  Puscas, Ioan ^a,c   Coltau, Marcela ^a   Baican, Michael ^b   Domuta, Gabriela ^a  

^a Ctr Res Med Assit Simleu S   (Romania)

^b Klinik Wilkenberg   (Germany)

^c Ctr for Res and Medical Assistance   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE IV; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; OMEPRAZOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; STOMACH ULCER;

ADULT; ANIMALS; ANTI-ULCER AGENTS; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; ENZYME INHIBITORS; ERYTHROCYTES; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; HUMANS; ISOENZYMES; KIDNEY; KINETICS; LUNG; MALE; MIDDLE AGED; OMEPRAZOLE; SWINE;

EID: 0032765259     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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