Developmental toxicity studies of 2-(difluoromethyl)-dl-ornithine (DFMO) in rats and rabbits

Toxicological Sciences

Volumn 50, Issue 1, 1999, Pages 127-135

  Kirchner, D L ^a   Mercieca, M D ^a   Crowell, J A ^a   Levine, B S ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Cancer chemopreventive; Developmental toxicity; Difluoromethylornithine; Embryotoxicity; Fetotoxicity; Maternal toxicity; Ornithine decarboxylase; Polyamine; Rabbit; Rat; Skeletal; Teratology

Indexed keywords

EFLORNITHINE; ORNITHINE DECARBOXYLASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; DRUG SAFETY; EMBRYOTOXICITY; ENVIRONMENTAL EXPOSURE; FETOTOXICITY; FOOD INTAKE; NONHUMAN; PRENATAL EXPOSURE; RABBIT; RAT; SKELETON MALFORMATION; TERATOGENICITY;

ANIMALS; BODY WEIGHT; BONE AND BONES; CESAREAN SECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; EFLORNITHINE; ENZYME INHIBITORS; FEMALE; FETUS; MALE; MATERNAL-FETAL EXCHANGE; ORNITHINE DECARBOXYLASE; PARITY; PREGNANCY; RABBITS; RATS; SPECIFIC PATHOGEN-FREE ORGANISMS; TERATOGENS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0032764971     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/50.1.127     Document Type: Article

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