A micromethod for the in vitro micronucleus assay

Mutagenesis

Volumn 14, Issue 4, 1999, Pages 403-410

  Nesslany, Fabrice ^a   Marzin, Daniel ^a,b  

^a INSTITUT PASTEUR DE LILLE   (France)

^b UNIV LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AROCLOR 1254; CLASTOGEN; TOXIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENOTOXICITY; LEUKEMIA L 5178 Y; METABOLIC ACTIVATION; METHODOLOGY; MICRONUCLEUS TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SCREENING;

ANIMALS; BIOTRANSFORMATION; CELL LINE; CRICETINAE; CYTOCHALASIN B; LIVER; MICE; MICRONUCLEUS TESTS; MUTAGENS; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

ANIMALIA; CRICETINAE; MAMMALIA;

EID: 0032764344     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/14.4.403     Document Type: Article

References (38)

1. Ames, B.N., Mc Cann, J. and Yamasaki, E. (1975) Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test. Mutat. Res., 31, 347-364.
2. Booth, S.C., Mould, A.J., Shaw, A. and Yamasaki, E. (1983) The biological activity of 4-chloromethylbiphenyl, benzyl chloride and 4-hydroxymethyl in 4 short-term tests for carcinogenicity. A report of an individual study in the UKEMS genotoxicity trial 1981. Mutat. Res., 119, 121-123.
3. Borenfreud, E., Babich, H. and Martin-Alguacil, N. (1988) Comparison of two in vitro cytotoxicity assays: the neutral red (NR) and tetrazolium MTT tests. Toxicol. In Vitro, 2, 1-6.
4. Carter, B (1967) Effects of cytochalasins on mammalian cells. Nature, 21, 261-264.
5. +/--3.7.2C mouse lymphoma cells. Mutagenesis, 13, 427-434.
6. Dyrby, T. and Ingvardsen, P. (1983) Sensitivity of different E.coli and Salmonella strains in mutagenicity testing calculated on the basis of selected literature. Mutat. Res., 123, 47-60.
7. Elhajouji, A., Van Hummelen, P. and Kirsch-Volders, M. (1995) Indications for thresholds of chemically-induced in vitro in human lymphocytes. Environ. Mol. Mutagen., 26, 292-304.
8. Elhajouji, A., Tibaldi, F. and Kirsch-Volders, M. (1997) Indication for thresholds of chromosome non-disjunction versus chromosome lagging induced by spindle inhibitors in vitro in human lymphocytes. Mutagenesis, 12, 133-140.
9. Elhajouji, A., Cunha, M. and Kirsch-Volders, M. (1998) Spindle poisons can induce polyploidy by mitotic slippage and micronucleated mononucleates in the cytokinesis-block assay. Mutagenesis, 13, 193-198.
10. Fenech, M. and Morley, A.A. (1985) Measurement of micronuclei in lymphocytes. Mutat. Res., 147, 29-36.
11. Fenech, M. and Neville, S. (1992) Conversion of excision-repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes. Environ. Mol. Mutagen., 19, 27-36.
12. Fritzenschaf, H., Kohlpoth, M., Rusche, B. and Schiffmann, D. (1993) Testing of known carcinogens and noncarcinogens in the Syrian hamster embryo (SHE) micronucleus test in vitro; correlations with in vivo micronucleus formation and cell transformation. Mutat. Res., 319, 47-53.
13. Gocke, E., King, M.T., Eckardt, K. and Wild, D. (1981) Mutagenicity of cosmetics ingredients licensed by the European Communities. Mutat. Res., 90, 91-109.
14. Kirchner, S., Stopper, H., Papp, T., Eckert, I., Vig, B.K. and Schiffman, D. (1993) Cytogenetic changes in primary, immortalized and malignant mammalian cells. Toxicol. Lett., 67, 283-295.
15. Kirsch-Volders, M., Elhajouji, A., Cundari, E. and Van Hummelen P. (1997) The in vitro micronucleus test: a multi endpoint assay to detect simultaneously mitotic delay, apoptosis, chromosome breakage, chromosome loss and non-disjunction. Mutat. Res., 392, 19-30.
16. Kolber, M.A., Broschat, K.O. and Landa-Gonzales, B. (1990) Cytochalasin B induces cellular DNA fragmentation. FASEB J., 4, 3021-3027.
17. Krishna, G., Kropko, M.L. and Theiss, J.C. (1989) Use of the cytokinesis-block method for the analysis of micronuclei in V79 Chinese hamster lung cells: results with mitomycin C. Mutat. Res., 222, 63-69.
18. Lasne, C., Gu, Z.W., Venegas, W. and Chouroulinkovi, I. (1984) The in vitro micronucleus assay for cytogenetic effects induced by mutagen-carcinogens: comparison with the in vitro sister-chromatid exchange assay. Mutat. Res., 130, 273-282.
19. Lynch, A.M. and Parry, J.M. (1993) The cytochalasin-B micronucleus/ kinetochore assay in vitro: studies with 10 suspected aneugens. Mutat. Res., 287, 71-86.
20. Maron, D.M. and Ames, B.N. (1983) Revised methods for the Salmonella mutagenicity test. Mutat. Res., 113, 173-215.
21. Marzin, D. (1997) The position of the in vitro micronucleus test within the battery of screening for genotoxic potential determination and regulation and the regulatory guidelines. Mutat. Res., 392, 175-181.
22. Matsuoka, A., Yamazaki, N., Suzuki, T., Hayashi, M. and Sofuni, T. (1993) Evaluation of the micronucleus test using a Chinese hamster cell line as an alternative to the conventional in vitro chromosomal aberration test. Mutat. Res., 272, 223-236.
23. Migliore, L. and Nieri, M. (1991) Evaluation of twelve potential aneuploidogenic chemicals by the in vitro human lymphocyte micronucleus assay. Toxicol. In Vitro, 5, 325-336.
24. Miller, B.M., Pujadas, E. and Gocke, E. (1995) Evaluation of the micronucleus test in vitro using Chinese hamster cells: results of four chemicals weakly positive in the in vivo micronucleus test. Environ. Mol. Mutagen., 26, 240-247.
25. Natarajan, A.T and van Kesteren-van Leeuwen, A.C. (1981) Mutagenic activity of 20 coded compounds in chromosome aberrations/sister chromatid exchanges assay using Chinese hamster ovary (CHO) cells. In de Serres, F.J. and Ashby (eds), Progress in Mutation Research, Vol. 1: Evaluation of Short-Term Tests for Carcinogens. Elsevier, Amsterdam, The Netherlands, pp. 551-559.
26. Prival, M.J., Bell, S.J., Mitchell, V.D., Peiperl M.D. and Vaughan, V.L. (1984) Mutagenicity of benzidine and benzidine-congener dyes and selected monoazo dyes in a modified Salmonella assay. Mutat. Res., 136, 33-47.
27. Seelbach, A., Fissler, B., Strohbusch, A. and Madle, S. (1993) Development of a modified micronucleus assay in vitro for detection of aneugenic effects. Toxicol. In Vitro, 7, 185-193.
28. Sina, J.F., Bean, C.L., Dysart, G.R., Taylor, V.I. and Bradley, M.O. (1983) Evaluation of the alkaline elution/rat hepatocyte assay as a predictor of carcinogenic/mutagenic potential. Mutat. Res., 113, 357-391.
29. Sofuni, T., Honma, M., Hayashi, M., Shimada, H., Tanaka, N., Wakuri, S., Awogi, T., Yamamoto, K.I., Nishi, Y. and Nakadate, M. (1996) Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: interim report of an international collaborative study. Mutagenesis, 11, 349-355.
30. Stopper, H., Körber, C., Spencer, D.L., Kirchner, S., Caspary, W.J. and Schiffmann, D. (1993a) An investigation of micronucleus and mutation induction by oxazepam in mammalian cells. Mutagenesis, 8, 449-455.
31. Stopper, H., Körber, C., Schiffmann, D. and Caspary, W.J. (1993b) Cell-cycle dependent micronucleus formation and mitotic disturbances induced by 5-azacytidine in mammalian cells. Mutat. Res., 300, 165-177.
32. Stopper, H., Eckert, I., Schiffmann, D., Spencer, D.L. and Caspary, W.J. (1994) Is micronucleus induction by aneugens an early event leading to mutagenesis? Mutagenesis, 9, 411-416.
33. +/- cell line is heterozygous for a codon 170 mutation in the p53 tumor suppressor gene. Mutat. Res., 373, 157-165.
34. Van Hummelen, P. and Kirsch-Volders, M. (1992) Analysis of eight known or suspected aneugens by the in vitro human lymphocyte micronucleus test. Mutagenesis, 7, 447-455.
35. Vian, L., Bichet, N. and Gouy, D. (1993) The in vitro micronucleus test on isolated lymphocytes. Mutat. Res., 291, 93-102.
36. Vian, L., Van Hummelen, P., Bichet, N., Gouy, D. and Kirsch-Volders, M. (1995) Evaluation of hydroquinone and chloral hydrate on the in vitro micronucleus test on isolated lymphocytes. Mutat. Res., 334, 1-7.
37. Villani, P., Olivero, S. and Botta, A. (1995) Cytokinesis-block micronucleus assay in cultured human T lymphocytes: evaluation of a threshold value for spontaneous micronuclei. Med. Sci. Res., 23, 529-531.
38. Zhang, L.S., Honma, M. Hayashi, M., Suzuki, T., Matsuoka, A. and Sofuni, T. (1995) A comparative study of TK6 human lymphoblastoid and L5178Y mouse lymphoma cell lines in the in vitro micronucleus test. Mutat. Res., 347, 105-115.