Potentiation of the hypotensive effect of adrenomedullin in pregnant rats

European Journal of Pharmacology

Volumn 385, Issue 2-3, 1999, Pages 129-136

  Makino, Ikuko ^a   Shibata, Kazuhiko ^a   Makino, Yasuo ^a   Kangawa, Kenji ^b   Kawarabayashi, Tatsuhiko ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Adrenomedullin; Blood pressure; Pregnancy; Rat

Indexed keywords

ADRENOMEDULLIN; ESTRADIOL; PROGESTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DEPRESSOR RESPONSE; DOSE RESPONSE; FEMALE; GENE EXPRESSION REGULATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT;

EID: 0032763989     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00670-6     Document Type: Article

References (41)

1. Baylis C., Tamas S., Conrad K. Importance of nitric oxide in control of systemic and renal hemodynamics during normal pregnancy: studies in the rat and implication for pre-eclampsia. Hypertension in Pregnancy. 15:1996;147-169.
2. Castro L.C., Allen R.J., Arora C.P., Hobel C.J., Platt L.D. Effect of pregnancy on the vasodepressor response to atrial natriuretic factor. Am. J. Obstet. Gynecol. 168:1993;979-984.
3. Conrad K.P., Colpoys M.C. Evidence against the hypothesis that prostaglandins are the vasodepressor agents of pregnancy: serial studies in chronically instrumented conscious rats. J. Clin. Invest. 77:1986;236-245.
4. Cormier-Regard S., Nguyen S.V., Claycomb W.C. Adrenomedullin gene expression is developmentally regulated and induced by hypoxia in rat ventricular cardiac myocytes. J. Biol. Chem. 273:1998;17787-17792.
5. Crandall M.E., Heesch C.M. Baroreflex control of sympathetic outflow in pregnant rats: effects of captopril. Am. J. Physiol. 258:1990;R1417-R1423.
6. Cumbee S., Nair U., Bishop V.S. Effects of pregnancy on the gain of arterial baroreflex control of RSNA in conscious rabbits. Fed. Proc. 45:1986;296. (Abstract).
7. Cunningham F.G., MacDonald P.C., Gant N.F. The placental hormones. Williams Obstetrics. 18 edn. 1989;67-85 Appleton and Lange, East Norwalk, CT.
8. Demey-Ponsart E., Foidar J.M., Sulon J., Sodoyez J.C. Serum CBG, free and total cortical and circadian patterns of adrenal function in normal pregnancy. J. Steroid Biochem. 16:1982;165-169.
9. Di Iorio R., Merinoni E., Scavo D., Letizia C., Cosmi E.V. Adrenomedullin in pregnancy. Lancet. 349:1997;328.
10. Gant N.F., Daley G.L., Chand S., Whalley P.J., MacDonald P.C. A study of angiotensin II pressor response throughout primigravid pregnancy. J. Clin. Invest. 52:1973;2682-2689.
11. Hattori Y., Murakami Y., Atsuta H., Minamino N., Kangawa K., Kasai K. Glucocorticoid regulation of adrenomedullin in a rat model of endotoxic shock. Life Sci. 62:1998;PL181-PL189.
12. Hettiaratchi E.S.G., Pickford M. The effect of oestrogen and progesterone on the pressor action of angiotensin in the rat. J. Physiol. London. 196:1968;447-451.
13. Itahara Y., Watanabe T.X., Inui T., Chino N., Kimura T., Sakakibara S. Analysis of hypotensive mechanisms of human and rat adrenomedullin in anesthetized rat. Jpn. J. Pharmacol. 64(Suppl. 1):1994;145.
14. Kapas S., Catt K.J., Clark A.J. Cloning and expression of cDNA encoding a rat adrenomedullin receptor. J. Biol. Chem. 270:1995;25344-25347.
15. Kawasaki H., Takasaki K., Furukawa T. Exaggerated pressor response to centrally administered renin in freely moving, spontaneously hypertensive rats. Eur. J. Pharmacol. 138:1987;351-358.
16. Keller-Wood M. Inhibition of basal and stimulated ACTH by cortisol during ovine pregnancy. Am. J. Physiol. 271:1996;R130-R136. (Regul. Integr. Comp. Physiol.).
17. Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Nakamura S., Matsui H., Eto H. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem. Biophys. Res. Commun. 192:1993;553-560.
18. Kitamura K., Sakata J., Kangawa K., Kojima M., Matsuo H., Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem. Biophys. Res. Commun. 194:1993;720-725.
19. Kitamura K., Ichiki Y., Tanaka M., Kawamota M., Emura J., Sakakibara S., Kangawa K., Matsuo H., Eto T. Immunoreactive adrenomedullin in human plasma. FEBS Lett. 342:1994;288-290.
20. 2 receptor mRNA level after global ischemia in rat brain. Neuropeptides. 30:1996;596-601.
21. G-nitro-L-arginine methyl ester. Eur. J. Pharmacol. 371:1999;159-167.
22. Marinoni E., Di Iorio R., Letizia C., Villaccio B., Scucchi L. Immunoreactive adrenomedullin in human fetoplacental tissues. Am. J. Obstet. Gynecol. 179:1998;784-787.
23. Martínez A., Miller M.-J., Unsworth E.J., Siegfried J.M., Cuttitta F. Expression of adrenomedullin in normal human lung and in pulmonary tumors. Endocrinology. 136:1995;4099-4105.
24. Martínez A., Weaver C., López J., Bhathena S.J., Elsasser T.H., Miller M.-J., Moody T.W., Unsworth E.J., Cuttitta F. Regulation of insulin secretion and blood glucose metabolism by adrenomedullin. Endocrinology. 137:1996;2626-2632.
25. McLaughlin M.K., Quinn P., Farnham J.G. Vascular reactivity in the hind limb of the pregnant ewe. Am. J. Obstet. Gynecol. 152:1985;593-598.
26. Minamino N., Shoji H., Sugo S., Kangawa K., Matsuo H. Adrenocortical steroids, thyroid hormones and retinoic acid augment the production of adrenomedullin in vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 211:1995;686-693.
27. Nakamura T., Matsui K., Ito M., Yoshimura T., Kawasaki N., Fujisaki S., Okamura H. Effects of pregnancy and hormone treatments on pressor response to angiotensin II in conscious rats. Am. J. Obstet. Gynecol. 159:1988;989-995.
28. Nathan L., Cuevas J., Chaudhuri G. The role of nitric oxide in the altered vascular reactivity of pregnancy in the rat. Br. J. Pharmacol. 114:1995;955-960.
29. Nishikimi T., Kitamura K., Saito Y., Shimada K., Ishimitsu T., Takamiya M., Kangawa K., Matsuo H., Eto T., Omae T., Matsuoka H. Clinical studies on the sites of production and clearance of circulating adrenomedullin in human subjects. Hypertension. 24:1994;600-604.
30. Novak K., Kaufman S. Effect of pregnancy, estradiol, and progesterone on pressor responsiveness to angiotensin II. Am. J. Physiol. 261:1991;R1164-R1170.
31. Paller M.S. Mechanism of decreased pressor responsiveness to ANG II, NE, and vasopressin in pregnant rats. Am. J. Physiol. 247:1984;H100-H108. (Heart Circ. Physiol. 16).
32. Parkes D.G., May C.N. Direct cardiac and vascular actions of adrenomedullin in conscious sheep. Br. J. Pharmacol. 120:1997;1179-1185.
33. Poston L., McCarthy A.L., Ritter J.M. Control of vascular resistance in the maternal and fetoplacental arterial beds. Pharmacol. Ther. 65:1995;215-239.
34. Shibata K., Sakimura M., Furukawa T. Antagonism of central pressor response to angiotensin II by α-human atrial natriuretic polypeptide at the preoptic area and posterior hypothalamus in rats. Neuropharmacology. 32:1993;175-184.
35. Shibata K., Makino I., Shibaguchi H., Niwa M., Katsuragi T., Furukawa T. Upregulation of angiotensin type 2 receptor mRNA by angiotensin II in rat cortical cells. Biochem. Biophys. Res. Commun. 239:1997;633-637.
36. Slangen B.F., Out I.C., Verkeste C.M., Peeters L.H. Systemic hemodynamics and oxygen transport during pregnancy in chronically instrumented conscious rats. Am. J. Physiol. 270:1996;H1779-H1784.
37. Sugo S., Minamino N., Kangawa K., Miyamoto K., Kitamura K., Sakata J., Eto T., Matsuo H. Endothelial cells activity synthesize and secrete adrenomedullin. Biochem. Biophys. Res. Commun. 201:1994;1160-1166.
38. Tamai T., Matsuura S., Tatsumi N., Nuntani T., Sagawa N. Role of sex steroid hormones in relative refractoriness to angiotensin II during pregnancy. Am. J. Obstet. Gynecol. 149:1984;177-183.
39. Upton P.D., Austin C., Taylor G.M., Nandha K.A., Clark A.J.L., Ghatei M.A., Bloom S.R., Smith D.M. Expression of adrenomedullin (ADM) and its binding sites in the rat uterus: increased number of binding sites and ADM messenger ribonucleic acid in 20-day pregnant rats compared with non-pregnant rats. Endocrinology. 138:1997;2508-2514.
40. White J.D., LaGamma E.F. Neuropeptide gene transcription in central and peripheral nervous system tissue by nuclear run-on assay. Methods Enzymol. 168:1989;681-690.
41. Yoshimura T., Ito M., Nakamura T., Kawasaki N., Matsui K., Nakayama M., Maeyama M. Effect of pregnancy and estrogen on the angiotensin II pressor response of the rabbit using serial systolic blood pressure measurements in the ear. Clin. Exp. Hypertens. B. 3:1984;97-109.