Melanocortins and the treatment of nervous system disease. Potential relevance to the skin?

Annals of the New York Academy of Sciences

Volumn 885, Issue , 1999, Pages 342-349

  Gispen, Willem Hendrik ^a   Adan, Roger A H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4 (METHYLSULFONYL)BUTYRYLGLUTAMYLHISTIDYLPHENYLALANYL DEXTRO LYSYLPHENYLALANINE; CISPLATIN; MELANOCORTIN; MELANOCORTIN RECEPTOR;

ANIMAL BEHAVIOR; BRAIN FUNCTION; CLINICAL TRIAL; CONFERENCE PAPER; HUMAN; INTRANASAL DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; NERVE GROWTH; NEUROIMMUNOLOGY; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; ORAL DRUG ADMINISTRATION; OVARY CARCINOMA; RECEPTOR UPREGULATION; SKIN CARE; SKIN FUNCTION; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0032763010     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1999.tb08689.x     Document Type: Conference Paper

References (35)

1. 1. De Wied, D. 1969. Effects of peptide hormones on behavior. In Frontiers in Neuroendocrinology. W.F. Ganong & L. Martini, Eds.: 97-140.
2. 2. Dunn, A.J. & P. Schotman. 1986. Effects of ACTH and related peptides on cerebral RNA and protein synthesis. In Neuropeptides and Behavior, vol. 1, CNS Effects of ACTH, MSH and Opioid Peptides. D. De Wied, W.H. Gispen & T.B. Van Wimersma Greidanus, Eds.: 165-187. Pergamon Press, Oxford.
3. 3. De Graan, P.N.E., P. Schotman & D.H.G. Versteeg. 1990. Neural mechanisms of action of neuropeptides: macromolecules and neurotransmitters. In Neuropeptides: Basics and Perspectives. D. De Wied, Ed.: 139-172. Elsevier Science Publishers B.V. Amsterdam.
4. 4. Hol, E.M., W.H. Gispen & P.R. Bar. 1995. ACTH-related peptides: receptors and signal transduction systems involved in their neurotrophic and neuroprotective actions. Peptides 16: 979-993.
5. 5. Gispen, W.H., J. Verhaagen & D. Bar. 1994. ACTH/MSH-derived peptides and peripheral nerve plasticity: neuropathies, neuroprotection and repair. Prog. Brain Res. 100: 223-229.
6. 6. Swaab, D.F., M. Visser & F.J. Tilders. 1976. Stimulation of intra-uterine growth in rat by alpha-melanocyte-stimulating hormone. J. Endocrinol. 70: 445-455.
7. 7. Van der Helm-Hylkema, H. & D. De Wied. 1976. Effect of neonatally injected ACTH and ACTH analogues on eye-opening of the rat. Life Sci. 18: 1099-1104.
8. 8. Strand, F.L., K.A. Williams, S.E. Alves, F.J. Antonawich, T.S. Lee, S.J. Lee, J. Kume & L.A. Zuccarelli. 1994. Melanocortins as factors in somatic neuromuscular growth and regrowth. Pharmacol. Ther. 62: 1-27.
9. 9. Strand, F.L., C. Saint-Come, T.S. Lee, S.J. Lee, J. Kume & L.A. Zuccarelli. 1993. ACTH/MSH(4-10) analog BIM 22015 aids regeneration via neurotrophic and myotrophic attributes. Peptides 14: 287-296.
10. 10. Strand, F.L. & T.T. Kung. 1980. ACTH accelerates recovery of neuromuscular function following crushing of peripheral nerve. Peptides 1: 135-138.
11. 11. Bijlsma, W.A., F.G.I. Jennekens, P. Schotman & W.H. Gispen. 1981. Effects of corticotropin (ACTH) on recovery of sensorimotor function in the rat: structure-activity study. Eur. J. Pharmacol. 76: 73-79.
12. 12. Van Der Zee, C.E.E.M., J.H. Brakkee & W.H. Gispen. 1991. Putative neurotrophic factors and functional recovery from peripheral nerve damage in the rat. Br. J. Pharmacol. 103: 1041-1046.
13. 13. Verhaagen, J., P.M. Edwards, F.G.I. Jennekens, P. Schotman & W.H. Gispen. 1986. α-Melanocyte stimulating hormone stimulates the outgrowth of myelinated nerve fibers after peripheral nerve crush. Exp. Neurol. 92: 451-454.
14. 14. Hamers, F.P.T., C. Pette, B. Bravenboer, C.J. Vecht, J.P. Neijt & W.H. Gispen. 1993. Cisplatin-induced neuropathy in mature rats. Effects of the melanocortin-derived peptide ORG 2766. Cancer Chemo. Pharmacol. 32: 162-166.
15. 15. Van Kooten, B., H.A. Van Diemen, K.M. Groenhout, P.C. Huijgens, G.J. Ossen-Koppele, J.J. Nauta & J.J. Heimans. 1992. A pilot study on the influence of a corticotropin (4-9) analogue on Vinca alkaloid-induced neuropathy. Arch. Neurol. 49: 1027-1031.
16. 4-9 analogue ORG 2766 can improve existing neuropathy in streptozocin-induced diabetic rats. Acta Diabetol. 30: 21-24.
17. 17. Bravenboer, B., P.H. Hendrikse, P.L. Oey, A.C. Van Huffelen, C. Groenhout, W.H. Gispen & D.W. Erkelens. 1994. Randomized double-blind placebo-controlled trial to evaluate the effect of the ACTH4-9 analogue ORG 2766 in IDDM patients with neuropathy. Diabetologia 37: 408-413.
18. 18. Duckers, H.J., J. Verhaagen & W.H. Gispen. 1993. The neurotrophic analogue of ACTH(4-9), Org 2766, protects against experimental allergic neuritis. Brain 116: 1059-1075.
19. 4-9 protects against experimental allergic neuritis. Ann. N.Y. Acad. Sci. 680: 493-495.
20. 20. Chhajlani, V. & J.E.S. Wikberg. 1992. Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. FEBS Lett. 309: 417-420.
21. 21. Cone, R.D., D. Lu, S. Koppula, D.I. Vage, H. Klungland, B. Boston, W. Chen, D.N. Orth, C. Pouton & R.A. Kesterson. 1996. The melanocortin receptors: agonists, antagonists, and the hormonal control of pigmentation. Recent. Prog. Horm. Res. 51: 287-317; discussion 318.
22. 22. Gantz, I., H. Miwa, Y. Konda, Y. Shimoto, T. Tashiro, S.J. Watson, J. Del Valle & T. Yamada. 1993. Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. J. Biol. Chem. 268: 15174-15179.
23. 23. Mountjoy, K.G., L.S. Robbins, M.T. Mortrud & R.D. Cone. 1992. The cloning of a family of genes that encode the melanocortin receptors. Science 257: 1248-1251.
24. 24. Gantz, I., Y. Shimoto, Y. Konda, H. Miwa, C.J. Dickinson & T. Yamada. 1994. Molecular cloning, expression, and characterization of a fifth melanocortin receptor. Biochem. Biophys. Res. Commun. 200: 1214-1220.
25. 25. Gantz, I., T. Konda, T. Tashiro, Y. Shimoto, H. Miwa, G. Munzert, S.J. Watson, J. Del Valle & T. Yamada. 1993. Molecular cloning of a novel melanocortin receptor. J. Biol. Chem. 268: 8246-8250.
26. 26. Roselli-Rehfuss, L., K.G. Mountjoy, L.S. Robbins, M.T. Mortrud, M.J. Low, J.B. Tatro, M.L. Entwistle, R.B. Simerly & R.D. Cone. 1993. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc. Natl. Acad. Sci. USA 90: 8856-8860.
27. 27. Adan, R.A.H., R.D. Cone, J.P. Burbach & W.H. Gispen. 1994. Differential effects of melanocortin peptides on neural melanocortin receptors. Mol. Pharmacol. 46: 1182-1190.
28. 28. Van Der Zee, C.E.E.M., J.H. Brakkee & W.H. Gispen. 1988. αMSH and Org2766 in peripheral nerve regeneration: different routes of delivery. Eur. J. Pharmacol. 147: 351-357.
29. 29. Adan, R.A.H., M. Van der Kraan, R.P. Doornbos, P.R. Bar, J.P. Burbach & W.H. Gispen. 1996. Melanocortin receptors mediate alpha-MSH-induced stimulation of neurite outgrowth in neuro 2A cells. Brain Res. Mol. Brain Res. 36: 37-44.
30. 30. Ferrari, W. 1958. Behavioural changes in animals after intracisternal injection with adrenocoticotrophic hormone and melanocyte stimulating hormone. Nature (Lond.) 181: 925-926.
31. 31. Spruijt, B.M., J.A.R.A.M. Van Hooff & W.H. Gispen. 1992. Ethology and neurobiology of grooming behavior. Physiol. Rev. 72: 825-852.
32. 32. Adan, R.A.H., J. Oosterom, G. Ludvigsdottir, J.H. Brakkee, J.P. Burbach & W.H. Gispen. 1994. Identification of antagonists for melanocortin MC3, MC4, and MC5 receptors. Eur. J. Pharmacol. 269: 331-337.
33. 33. Floris, E. 1963. Effect dellíniezone endorachnidea nell'uoma di ACTH. Boll. Soc. Ital. Viol. Sper. 558-560.
34. 34. Wessells, H., K. Fuciarelli, J. Hansen, M.E. Hadley, V.J. Hruby, R. Dorr & N. Levine. 1998. Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study. J. Urol. 160: 389-393.
35. 35. Chen, W., M.A. Kelly, X. Opitz-Araya, R.E. Thomas, M.J. Low & R.D. Cone. 1997. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell 91: 789-798.