Differential expression of facilitative glucose transporter (GLUT) genes in primary lung cancers and their liver metastases

Japanese Journal of Cancer Research

Volumn 90, Issue 11, 1999, Pages 1238-1243

  Kurata, Takayasu ^a   Oguri, Tetsuya ^a   Isobe, Takeshi ^a   Ishioka, Shin Ichi ^a   Yamakido, Michio ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

GLUT1; GLUT3; GLUT5; Lung cancer; Metastatic lesion

Indexed keywords

GLUCOSE TRANSPORTER;

ADULT; AGED; ARTICLE; AUTOPSY; CANCER CELL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN TISSUE; LIVER CANCER; LIVER METASTASIS; LUNG CANCER; LUNG PARENCHYMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032762469     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1999.tb00702.x     Document Type: Article

References (27)

1. Hatanaka, M. Transport of sugars in tumor cell membranes. Biochim. Biophys. Acta, 355, 77-104 (1974).
2. Isselbacher, K. J. Sugar and amino acid transport by cells in culture - differences between normal and malignant cells. N. Engl. J. Med., 286, 929-933 (1972).
3. Holm, E., Hagmüller, E., Staedt, U., Schlickeiser, G., Günther, H.-J., Leweling, H., Tokus, M. and Kollmar, H. B. Substrate balances across colonic carcinomas in Humans. Cancer Res., 55, 1373-1378 (1995).
4. Mueckler, M., Caruso, C., Baldwin, S. A., Panico, M., Blench, I., Morris, H. R., Allard, W. J., Lienhard, G. E. and Lodish, H. F. Sequence and structure of a human glucose transporter. Science, 229, 941-945 (1985).
5. Fukumoto, H., Seino, S., Imura, H., Seino, Y., Eddy, R. L., Fukushima, Y., Byers, M. G., Shows, T. B. and Bell, G. I. Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein. Proc. Natl. Acad. Sci. USA, 85, 5434-5438 (1988).
6. Kayano, T., Fukumoto, H., Eddy, R. L., Fan, Y.-S., Byers, M. G., Shows, T. B. and Bell, G. I. Evidence for a family of human glucose transporter-like proteins: sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues. J. Biol. Chem., 263, 15245-15248 (1988).
7. Fukumoto, H., Kayano, T., Buse, J. B., Edwards, Y., Pilch, P. F., Bell, G. I. and Seino, S. Cloning and characterization of the major insulin-responsive glucose transporter expressed in human skeletal muscle and other insulin-responsive tissues. J. Biol. Chem., 264, 7776-7779 (1989).
8. Kayano, T., Burant, C. F., Fukumoto, H., Gould, G. W., Fan, Y.-S., Eddy, R. L., Byers, M. G., Shows, T. B., Seino, S. and Bell, G. I. Human facilitative glucose transporters: isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6). J. Biol. Chem., 265, 13276-13282 (1990).
9. Waddell, I. D., Zomerschoe, A. G., Voice, M. W. and Burchell, A. Cloning and expression of a hepatic microsomal glucose transport protein: comparison with liver plasma-membrane glucose-transport protein GLUT2. Biochem. J., 286, 173-177 (1992).
10. Pessin, J. E. and Bell, G. I. Mammalian facilitative glucose transporter family: structure and molecular regulation. Annu. Rev. Physiol., 54, 911-930 (1992).
11. Mueckler, M. Facilitative glucose transporters. Eur. J. Biochem., 219, 713-725 (1994).
12. Takata, K., Kasahara, T., Kasahara, M., Ezaki, O. and Hirano, H. Erythrocyte/HepG2-type glucose transporter is concentrated in cells of blood-tissue barriers. Biochem. Biophys. Res. Commun., 173, 67-73 (1990).
13. Yamamoto, T., Seino, Y., Fukumoto, H., Koh, G., Yano, H., Inagaki, N., Yamada, Y., Inoue, K., Manabe, T. and Imura, H. Over-expression of facilitative glucose transporter genes in human cancer. Biochem. Biophys. Res. Commun., 170, 223-230 (1990).
14. Brown, R. S. and Wahl, R. L. Overexpression of Glut-1 glucose transporter in human breast cancer. Cancer, 72, 2979-2985 (1993).
15. Mellanen, P., Minn, H., Grénman, R. and Härkönen, P. Expression of glucose transporters in head-and-neck tumors. Int. J. Cancer, 56, 622-629 (1994).
16. Younes, M., Lechago, L. V., Somoano, J. R., Mosharaf, M. and Lechago, J. Wide expression of the human erythrocyte glucose transporter Glut1 in human cancers. Cancer Res., 56, 1164-1167 (1996).
17. Haber, R. S., Weiser, K. R., Pritsker, A., Reder, I. and Burstein, D. E. GLUT1 glucose transporter expression in benign and malignant thyroid nodules. Thyroid, 7, 363-367 (1997).
18. Ogawa, J., Inoue, H. and Koide, S. Glucose-transporter-type-I-gene amplification correlates with sialyl-Lewis-X synthesis and proliferation in lung cancer. Int. J. Cancer, 74, 189-192 (1997).
19. Younes, M., Lechago, L. V., Somoano, J. R., Mosharaf, M. and Lechago, J. Immunohistochemical detection of Glut3 in human tumors and normal tissues. Anticancer Res., 17, 2747-2750 (1997).
20. Zamora-León, S. P., Golde, D. W., Concha, I. I., Rivas, C. I., Delgado-López, F., Baselga, J., Nualart, F. and Vera, J. C. Expression of the fructose transporter GLUT5 in human breast cancer. Proc. Natl. Acad. Sci. USA, 93, 1847-1852 (1996).
21. Younes, M., Brown, R. W., Stephenson, M., Gondo, M. and Cagle, P. T. Overexpression of Glut1 and Glut3 in Stage I nonsmall cell lung carcinoma is associated with poor survival. Cancer, 80, 1046-1051 (1997).
22. Ito, T., Noguchi, Y., Satoh, S., Hayashi, H., Inayama, Y. and Kitamura, H. Expression of facilitative glucose transporter isoforms in lung carcinomas: its relation to histologic type, differentiation grade, and tumor stage. Mod. Pathol., 11, 437-443 (1998).
23. Oguri, T., Fujiwara, Y., Isobe, T., Katoh, O., Watanube, H. and Yamakido, M. Expression of γ-glutamylcysteine synthetase (γ-GCS) and multidrug resistance-associated protein (MRP), but not human canalicular multispecific organic anion transporter (cMOAT), genes correlates with exposure of human lung cancers to platinum drugs. Br. J. Cancer, 77, 1089-1096 (1998).
24. Kan, O., Baldwin, S. A. and Whetton, A. D. Apoptosis is regulated by the rate of glucose transport in an interleukin 3 dependent cell line. J. Exp. Med., 180, 917-923 (1994).
25. Shim, H., Chun, Y. S., Lewis, B. C. and Dang, C. V. A unique glucose-dependent apoptotic pathway induced by c-Myc. Proc. Natl. Acad. Sci. USA, 95, 1511-1516 (1998).
26. Martell, R. L., Slapak, C. A. and Levy, S. B. Effect of glucose transport inhibitors on vincristine efflux in multidrug-resistant murine erythroleukaemia cells overexpressing the multidrug resistance-associated protein (MRP) and two glucose transport proteins, GLUT1 and GLUT3. Br. J. Cancer, 75, 161-168 (1997).
27. Vera, J. C., Castillo, G. R. and Rosen, O. M. A possible role for a mammalian facilitative hexose transporter in the development of resistance to drugs. Mol. Cell. Biol. 11, 3407-3418 (1991).